ARHGEF15 and CEP55

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ARHGEF15	CEP55
Gene Name		Rho guanine nucleotide exchange factor (GEF) 15	centrosomal protein 55kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Dendrite	Centrosome Centriole Membrane Midbody Cleavage Furrow Intercellular Bridge
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Rho GTPase Activity Regulation Of Catalytic Activity Positive Regulation Of Stress Fiber Assembly Retina Vasculature Morphogenesis In Camera-type Eye Negative Regulation Of Synapse Maturation	Mitotic Cytokinesis Cell Separation After Cytokinesis Nucleus Organization Mitotic Metaphase Plate Congression Establishment Of Protein Localization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: C11orf49 CEP55 EPHA4 ESR1 ESRRG LASP1 MOB4 PIN1	55 interactors: AKAP9 ANXA11 ARHGEF15 C1orf109 CCBE1 CCDC53 CCHCR1 CDC45 CDK1 CDSN CEP57L1 DTNB ECSIT EIF1AD FAM90A1 FBF1 FXR2 GOLGA8DP HAUS1 HGS KIFC3 MAPK1 MAPK1IP1L MFAP1 MIA3 MORF4L2 MUM1 NOS3 PCNT PDCD6IP PEF1 PIN1 PLEKHG6 PLK1 POLM POM121 PPP1R16B PSEN2 PTPN23 RAB3D RBM17 RBM22 RCOR3 RNF32 SDCBP SNRPB SNW1 SSX2IP TCL1A TEAD4 TEX14 TFG TSG101 VPS37C VPS37D
Entrez ID		22899	55165
HPRD ID		10535	12569
Ensembl ID		ENSG00000198844	ENSG00000138180
Uniprot IDs		O94989	Q53EZ4
PDB IDs			3E1R
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity Steroid Hormone Mediated Signaling Pathway Fasciculation Of Motor Neuron Axon Hormone-mediated Signaling Pathway Fasciculation Of Sensory Neuron Axon Prostate Epithelial Cord Elongation Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Negative Regulation Of Axon Regeneration Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Branch Elongation Involved In Mammary Gland Duct Branching Antral Ovarian Follicle Growth DNA-templated Transcription, Initiation Regulation Of Branching Involved In Prostate Gland Morphogenesis Mammary Gland Branching Involved In Pregnancy Regulation Of Rho GTPase Activity Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Positive Regulation Of Cellular Metabolic Process Regulation Of Rho Protein Signal Transduction Corticospinal Tract Morphogenesis Vagina Development Positive Regulation Of Signal Transduction Regulation Of Axon Regeneration Uterus Development Regulation Of Signal Transduction Cellular Response To Organic Cyclic Compound Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Nitric-oxide Synthase Activity Cell Separation After Cytokinesis Regulation Of Rap GTPase Activity Cellular Response To Estradiol Stimulus Prostate Gland Growth Regulation Of Rac GTPase Activity Branching Involved In Prostate Gland Morphogenesis Negative Regulation Of Intracellular Signal Transduction Cellular Response To Lipid Mammary Gland Epithelial Cell Proliferation Female Genitalia Development Axonal Fasciculation Regulation Of Rap Protein Signal Transduction Regulation Of Signaling Positive Regulation Of Monooxygenase Activity Branch Elongation Of An Epithelium	Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Localization Establishment Of Protein Localization Virion Assembly Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Exocytosis Protein Transport Viral Protein Processing Positive Regulation Of Transport Mitotic Cell Cycle Process Regulation Of Vesicle-mediated Transport Cell Cycle Regulation Of Exocytosis Mitotic Cell Cycle Organelle Organization Cell Division Microtubule Cytoskeleton Organization Positive Regulation Of Extracellular Vesicular Exosome Assembly Intracellular Transport Of Virus Cell Cycle Process Regulation Of Cellular Localization Viral Life Cycle Centrosome Organization Membrane Organization Cellular Localization Mitotic Nuclear Envelope Disassembly Positive Regulation Of Metabolic Process Microtubule Organizing Center Organization Regulation Of Protein Metabolic Process Regulation Of Organelle Organization Anatomical Structure Development Nuclear Envelope Disassembly G2/M Transition Of Mitotic Cell Cycle Viral Process Microtubule-based Process Viral Budding Developmental Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Anatomical Structure Morphogenesis Cell Differentiation Regulation Of Signal Transduction Cellular Response To DNA Damage Stimulus Cell Projection Morphogenesis Regulation Of Early Endosome To Late Endosome Transport Cellular Protein Localization Cell Part Morphogenesis Regulation Of Cellular Component Organization Nuclear Envelope Organization
Tagcloud ?			atad2 birc5 cdkn2a cldn6 crypt ct26 epcam flt1 g12d gp70 hif1a homozygously immunome immunotherapies mabs mhc mki67 ms4a8a ms4a8b muc2 mutated nras pbk syngeneic synonymous top2a transcriptome trp53 undifferentiated
Tagcloud (Difference) ?			atad2 birc5 cdkn2a cldn6 crypt ct26 epcam flt1 g12d gp70 hif1a homozygously immunome immunotherapies mabs mhc mki67 ms4a8a ms4a8b muc2 mutated nras pbk syngeneic synonymous top2a transcriptome trp53 undifferentiated
Tagcloud (Intersection) ?