DSCR9 and COPB1

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		DSCR9	COPB1
Description		Down syndrome critical region 9	coat protein complex I subunit beta 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Membrane Membrane Coat COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle COPI-coated Vesicle Membrane Secretory Granule Membrane Cytoplasmic Vesicle Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Molecular_function	Structural Molecule Activity Protein Binding
	Biological Process	Biological_process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport
Pathways			Neutrophil degranulation COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Eye color traits ( 20463881) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)	HDL cholesterol ( 26780889) HDL cholesterol levels ( 28334899 32203549) Height ( 31562340) High chromosomal aberration frequency (total) ( 31586183) Hip circumference adjusted for BMI ( 34021172) Vitamin D levels ( 25208829)
Interacting Genes		146 interacting genes: ACTB ACTN4 ACTR3B ADAMTS8 ADGRB3 AKAP8L ALDOA APP ASB3 ASH1L ATXN10 BEX3 BFSP1 BICD2 BTBD1 CCDC6 CD74 CELSR3 CERCAM CIAO3 CLTC CLU CNKSR1 CNOT2 COPB1 COPS4 CREBZF CTSB CXXC5 DARS1 DCAF6 DDX3X DIS3L DNAJA1 DPYSL2 DST DYNC1H1 EFEMP1 EXTL3 EYA3 FAN1 FBH1 FBXL16 FBXO11 FN1 FN3K FUZ GAR1 GIT1 GNPTAB GPRASP2 GUCY1B1 HDAC6 HNRNPK HPF1 HPS4 IFT122 IMMT ITCH JAKMIP1 KALRN KDM5A KIF1A KIF3A KLHL7 LMO7 LONRF1 LRP4 MACF1 MCRS1 METTL8 MIPOL1 MORF4L1 MTMR3 MTUS2 MYCBP2 NAGK NARS1 NBEA NCBP1 NDUFA10 NDUFB7 NEUROD6 NFE2L3 NIPBL NR4A2 OLR1 P4HTM PAK1 PAK2 PBXIP1 PCCB PDCD7 PDE4DIP PICK1 PIK3R4 PLEKHB1 PLXNB3 PPP4R1 PRKAR1A PSMC1 PSMD2 QRICH1 RAP1GAP RNF10 RSBN1L SBNO1 SEC23IP SESN3 SGSM2 SMPD3 SMURF2 SNX5 SPARCL1 SPOCK2 SPRED1 SPRY2 SPTBN1 STAMBP STX1A SULF1 SYNE1 TARS1 TNKS2 TPP1 TRIM5 TRIO TRIOBP TRIP12 TSG101 TTYH1 USP33 USP47 USP8 VARS1 VPS54 VPS9D1 WDR13 WDR26 WDR47 WRAP53 XAB2 XRN2 ZNF528 ZNFX1 ZRSR2	46 interacting genes: ADAM19 ANO1 APP ARCN1 ARF1 BCAR1 COPE COPG1 COPG2 DSCR9 ERBIN FOXB1 GORAB GRB2 GTPBP4 HLA-DPB1 HLA-G ID1 IRAK3 KCNK3 KDELR1 KIAA1328 LINC00839 LZTS1 LZTS2 NUB1 PDGFRB PRKCE PTEN RGS2 RGS4 RHOQ RNF10 SERTAD1 SNTA1 SPTBN1 TANK TAPBP TMED10 TRIM37 TTYH2 UBC UBQLN4 VPS18 WBP2 XRCC6
Entrez ID		257203	1315
HPRD ID		10925	02981
Ensembl ID		ENSG00000230366	ENSG00000129083
Uniprot IDs			P53618
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasm Cytoskeleton Macromolecule Metabolic Process Cytosol Protein Metabolic Process Post-translational Protein Modification Protein Modification Process Intracellular Protein Localization Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Amyloid Fibril Formation Small GTPase Binding Cytoskeleton-dependent Intracellular Transport Identical Protein Binding Regulation Of Signal Transduction Vesicle-mediated Transport Neuron Projection Morphogenesis Transport Along Microtubule Regulation Of Wnt Signaling Pathway Protein Modification By Small Protein Conjugation Cell Projection Morphogenesis Positive Regulation Of Cellular Component Organization Positive Regulation Of Microtubule Nucleation Regulation Of Cellular Component Organization Microtubule Negative Regulation Of Signal Transduction Organelle Organization Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Organelle Organization Catabolic Process Low-density Lipoprotein Particle Receptor Binding Axo-dendritic Transport Macromolecule Catabolic Process Protein Ubiquitination Regulation Of Microtubule Cytoskeleton Organization Regulation Of Signaling Microtubule-based Transport Regulation Of Supramolecular Fiber Organization Regulation Of Intracellular Signal Transduction Centrosome Nucleus Intracellular Transport Cellular Localization Axon Cytoplasm Regulation Of Cellular Response To Stress Regulation Of Cell Communication Establishment Of Protein Localization To Vacuole Platelet Alpha Granule Lumen Establishment Of Localization In Cell Regulation Of Intrinsic Apoptotic Signaling Pathway	COPI-coated Vesicle Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum COPI Vesicle Coat COPI-coated Vesicle Transport Vesicle Golgi Vesicle Transport Vesicle-mediated Transport Golgi Membrane Negative Regulation Of Glycine Import Across Plasma Membrane Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Establishment Of Protein Localization Positive Regulation Of Reactive Oxygen Species Metabolic Process Golgi Apparatus Regulation Of Actin Cytoskeleton Organization Regulation Of Biological Quality Cytoplasmic Vesicle Regulation Of Actin Filament-based Process Endoplasmic Reticulum-Golgi Intermediate Compartment Lumenal Side Of Endoplasmic Reticulum Membrane Regulation Of Cytoskeleton Organization Endoplasmic Reticulum Membrane Positive Regulation Of Excitatory Postsynaptic Potential Protein Transport Negative Regulation Of Organ Growth Intra-Golgi Vesicle-mediated Transport Peptide Antigen Binding Regulation Of Protein Metabolic Process Plasma Membrane Regulation Of Innate Immune Response Signaling Receptor Activator Activity Positive Regulation Of Macromolecule Biosynthetic Process Neuron Projection Organization Cytoplasm Positive Regulation Of Metabolic Process Modulation Of Chemical Synaptic Transmission Positive Regulation Of Biosynthetic Process Positive Regulation Of Multicellular Organismal Process Regulation Of Nervous System Process Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Cytokine Production Regulation Of Cellular Component Organization Membrane Regulation Of Supramolecular Fiber Organization Regulation Of Reactive Oxygen Species Metabolic Process Cellular Localization Regulation Of Intracellular Signal Transduction Intracellular Protein Localization Intracellular Protein Transport ER To Golgi Transport Vesicle Membrane Positive Regulation Of Tolerance Induction
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