COPB1 and NUB1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		COPB1	NUB1
Gene Name		coatomer protein complex, subunit beta 1	negative regulator of ubiquitin-like proteins 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Membrane COPI Vesicle Coat Intracellular Membrane-bounded Organelle	Nucleus Nucleolus Cytoplasm
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Viral Process COPI Coating Of Golgi Vesicle Membrane Organization	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Interferon-gamma Response To Tumor Necrosis Factor
Pathways		COPI Mediated Transport Golgi to ER Retrograde Transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		32 interactors: ADAM19 APP ARCN1 ARF1 COPE COPG1 COPG2 ERBB2IP FOXB1 GRB2 HLA-DPB1 HLA-G ID1 IRAK3 KCNK3 KDELR1 LZTS2 NUB1 PDGFRB PRKCE RGS2 RGS4 RHOQ SERTAD1 SNTA1 TANK TAPBP TMED10 TRIM37 UBQLN4 VPS18 XRCC6	12 interactors: AIPL1 COPB1 FANCA NEDD8 PSMD2 PSMD4 SF3B4 SNCAIP UBD UBE2K UFD1L VCP
Entrez ID		1315	51667
HPRD ID		02981	07450
Ensembl ID		ENSG00000129083	ENSG00000013374
Uniprot IDs		P53618	H3BM14 H3BM74 Q9Y5A7
PDB IDs			1WJU
Enriched GO Terms of Interacting Partners?		Retrograde Vesicle-mediated Transport, Golgi To ER COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Vesicle Targeting Localization Within Membrane Intracellular Transport Golgi Vesicle Transport Membrane Budding Vesicle-mediated Transport Establishment Of Localization In Cell Innate Immune Response Cellular Localization Immune Response-regulating Signaling Pathway Regulation Of Cytoskeleton Organization Immune Response Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Immune System Process Regulation Of MAPK Cascade Regulation Of Actin Filament-based Process Regulation Of Organelle Organization Regulation Of Phosphorylation Defense Response Protein Transport Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Organelle Localization ERBB Signaling Pathway Regulation Of Protein Metabolic Process Establishment Of Protein Localization Regulation Of Phosphorus Metabolic Process Regulation Of Actin Cytoskeleton Organization Regulation Of Immune Response Protein Localization Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Intracellular Protein Transport Positive Regulation Of Immune Response Negative Regulation Of MAP Kinase Activity Transport Organelle Localization Regulation Of Phospholipase Activity Regulation Of Immune System Process Antigen Processing And Presentation Of Peptide Antigen Cellular Copper Ion Homeostasis Cellular Protein Localization Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation	Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Modification By Small Protein Conjugation Proteolysis Protein Ubiquitination Catabolic Process Aggresome Assembly Regulation Of Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Protein Polyubiquitination Positive Regulation Of Protein Catabolic Process Regulation Of Proteolysis Cellular Protein Metabolic Process Cellular Protein Modification Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Proteolysis Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of Apoptotic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Cellular Response To Stress Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Death Cellular Response To DNA Damage Stimulus Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cellular Metabolic Process Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Ligase Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction In Response To DNA Damage Apoptotic Process
Tagcloud ?		ca037 ca530 cadd chlamydiaceae chlamydophila copd1 copd2 inca incc pkn5 psittaci scc1 scc2 scc3 sctc sctd sctj sctl sctn sctq sctr scts sctt sctu sctv sctw t3s t3ss tarp	anticathepsin autophagosome brilliantly cathepsins cytokeratin dendrite dendrites drebrin edd1 entirely eosinophilic globular granular homogenously immunohistochemically immunolabeled immunostained lc3 lysosome map2 marginal mgbs neocortex neurofilament p62 sequestered spherical tenth ultrastructurally
Tagcloud (Difference) ?		ca037 ca530 cadd chlamydiaceae chlamydophila copd1 copd2 inca incc pkn5 psittaci scc1 scc2 scc3 sctc sctd sctj sctl sctn sctq sctr scts sctt sctu sctv sctw t3s t3ss tarp	anticathepsin autophagosome brilliantly cathepsins cytokeratin dendrite dendrites drebrin edd1 entirely eosinophilic globular granular homogenously immunohistochemically immunolabeled immunostained lc3 lysosome map2 marginal mgbs neocortex neurofilament p62 sequestered spherical tenth ultrastructurally
Tagcloud (Intersection) ?