COPB1 and VPS18

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		COPB1	VPS18
Gene Name		coatomer protein complex, subunit beta 1	vacuolar protein sorting 18 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Membrane COPI Vesicle Coat Intracellular Membrane-bounded Organelle	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Actin Filament HOPS Complex Late Endosome Membrane
	Molecular Function	Structural Molecule Activity Protein Binding	Actin Binding Protein Binding Syntaxin Binding Protein Binding, Bridging Metal Ion Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Viral Process COPI Coating Of Golgi Vesicle Membrane Organization	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Endosome Organization Lysosome Organization Regulation Of SNARE Complex Assembly Viral Entry Into Host Cell
Pathways		COPI Mediated Transport Golgi to ER Retrograde Transport
Drugs
Diseases
GWAS			Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		32 interactors: ADAM19 APP ARCN1 ARF1 COPE COPG1 COPG2 ERBB2IP FOXB1 GRB2 HLA-DPB1 HLA-G ID1 IRAK3 KCNK3 KDELR1 LZTS2 NUB1 PDGFRB PRKCE RGS2 RGS4 RHOQ SERTAD1 SNTA1 TANK TAPBP TMED10 TRIM37 UBQLN4 VPS18 XRCC6	18 interactors: AKTIP COPB1 EP300 GGA1 GGA2 GGA3 HOOK1 MON1B STX1A STX6 STX7 STX8 UBE2D2 UVRAG VPS11 VPS16 VPS33A VPS45
Entrez ID		1315	57617
HPRD ID		02981	09776
Ensembl ID		ENSG00000129083	ENSG00000104142
Uniprot IDs		P53618	Q9P253
PDB IDs
Enriched GO Terms of Interacting Partners?		Retrograde Vesicle-mediated Transport, Golgi To ER COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Vesicle Targeting Localization Within Membrane Intracellular Transport Golgi Vesicle Transport Membrane Budding Vesicle-mediated Transport Establishment Of Localization In Cell Innate Immune Response Cellular Localization Immune Response-regulating Signaling Pathway Regulation Of Cytoskeleton Organization Immune Response Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Immune System Process Regulation Of MAPK Cascade Regulation Of Actin Filament-based Process Regulation Of Organelle Organization Regulation Of Phosphorylation Defense Response Protein Transport Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Organelle Localization ERBB Signaling Pathway Regulation Of Protein Metabolic Process Establishment Of Protein Localization Regulation Of Phosphorus Metabolic Process Regulation Of Actin Cytoskeleton Organization Regulation Of Immune Response Protein Localization Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Intracellular Protein Transport Positive Regulation Of Immune Response Negative Regulation Of MAP Kinase Activity Transport Organelle Localization Regulation Of Phospholipase Activity Regulation Of Immune System Process Antigen Processing And Presentation Of Peptide Antigen Cellular Copper Ion Homeostasis Cellular Protein Localization Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation See more	Vesicle-mediated Transport Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Transport Establishment Of Localization In Cell Intracellular Protein Transport Cellular Localization Vesicle Fusion Cellular Protein Localization Transport Organelle Fusion Vesicle Organization Membrane Fusion Vesicle Docking Endosomal Transport Early Endosome To Late Endosome Transport Membrane Docking Endosome To Lysosome Transport Endosome Organization Lysosomal Transport Vesicle Docking Involved In Exocytosis Membrane Organization Vacuolar Transport Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Organelle Organization Organelle Localization Viral Entry Into Host Cell Entry Into Host Cell Vesicle Localization Viral Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Protein Localization To Plasma Membrane Histone H2B Acetylation Regulation Of Vacuole Fusion, Non-autophagic Positive Regulation Of Receptor Localization To Synapse Regulation Of DNA-templated Transcription In Response To Stress Lysosome Organization Positive Regulation Of Protein Binding Exocytosis N-terminal Peptidyl-lysine Acetylation Regulation Of Protein Localization Cellular Response To Hypoxia Regulation Of Vesicle-mediated Transport Cellular Response To Decreased Oxygen Levels Interaction With Host Vacuole Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Cellular Response To Oxygen Levels Regulation Of Tubulin Deacetylation See more
Tagcloud ?		ca037 ca530 cadd chlamydiaceae chlamydophila copd1 copd2 inca incc pkn5 psittaci scc1 scc2 scc3 sctc sctd sctj sctl sctn sctq sctr scts sctt sctu sctv sctw t3s t3ss tarp
Tagcloud (Difference) ?		ca037 ca530 cadd chlamydiaceae chlamydophila copd1 copd2 inca incc pkn5 psittaci scc1 scc2 scc3 sctc sctd sctj sctl sctn sctq sctr scts sctt sctu sctv sctw t3s t3ss tarp
Tagcloud (Intersection) ?