COPB1 and RGS4

Number of citations of the paper that reports this interaction (PMID 10982407)
7

Data Source:
HPRD (two hybrid, in vivo)

		COPB1	RGS4
Gene Name		coatomer protein complex, subunit beta 1	regulator of G-protein signaling 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Membrane COPI Vesicle Coat Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol Plasma Membrane Protein Complex
	Molecular Function	Structural Molecule Activity Protein Binding	G-protein Alpha-subunit Binding GTPase Activator Activity Calmodulin Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Viral Process COPI Coating Of Golgi Vesicle Membrane Organization	Inactivation Of MAPK Activity Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways		COPI Mediated Transport Golgi to ER Retrograde Transport	Signaling by GPCR GPCR downstream signaling G alpha (z) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS
Protein-Protein Interactions		32 interactors: ADAM19 APP ARCN1 ARF1 COPE COPG1 COPG2 ERBB2IP FOXB1 GRB2 HLA-DPB1 HLA-G ID1 IRAK3 KCNK3 KDELR1 LZTS2 NUB1 PDGFRB PRKCE RGS2 RGS4 RHOQ SERTAD1 SNTA1 TANK TAPBP TMED10 TRIM37 UBQLN4 VPS18 XRCC6	12 interactors: CALM1 COPB1 COPB2 ERBB3 GABBR1 GNAI1 GNAI2 GNAO1 GNAQ KRIT1 PLCB1 PTAFR
Entrez ID		1315	5999
HPRD ID		02981	03947
Ensembl ID		ENSG00000129083	ENSG00000117152
Uniprot IDs		P53618	P49798
PDB IDs
Enriched GO Terms of Interacting Partners?		Retrograde Vesicle-mediated Transport, Golgi To ER COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Vesicle Targeting Localization Within Membrane Intracellular Transport Golgi Vesicle Transport Membrane Budding Vesicle-mediated Transport Establishment Of Localization In Cell Innate Immune Response Cellular Localization Immune Response-regulating Signaling Pathway Regulation Of Cytoskeleton Organization Immune Response Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Immune System Process Regulation Of MAPK Cascade Regulation Of Actin Filament-based Process Regulation Of Organelle Organization Regulation Of Phosphorylation Defense Response Protein Transport Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Organelle Localization ERBB Signaling Pathway Regulation Of Protein Metabolic Process Establishment Of Protein Localization Regulation Of Phosphorus Metabolic Process Regulation Of Actin Cytoskeleton Organization Regulation Of Immune Response Protein Localization Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Intracellular Protein Transport Positive Regulation Of Immune Response Negative Regulation Of MAP Kinase Activity Transport Organelle Localization Regulation Of Phospholipase Activity Regulation Of Immune System Process Antigen Processing And Presentation Of Peptide Antigen Cellular Copper Ion Homeostasis Cellular Protein Localization Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation	Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger G-protein Coupled Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Inositol Phosphate Metabolic Process Platelet Activation Regulation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Regulation Of Catalytic Activity Regulation Of Cyclase Activity Synaptic Transmission Wound Healing Regulation Of CAMP Biosynthetic Process Signal Transduction Cell Activation Response To Wounding COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Regulation Of CAMP Metabolic Process G-protein Coupled Acetylcholine Receptor Signaling Pathway Golgi Vesicle Budding Signaling Cell Communication Regulation Of Phosphorus Metabolic Process Blood Coagulation Hemostasis Positive Regulation Of Catalytic Activity Cell-cell Signaling Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Gamma-aminobutyric Acid Signaling Pathway Negative Regulation Of CAMP Biosynthetic Process Cellular Response To Stimulus Vesicle Targeting, To, From Or Within Golgi Regulation Of Calcium Ion Transport Negative Regulation Of CAMP Metabolic Process Dopamine Receptor Signaling Pathway Intracellular Signal Transduction Vesicle Organization Regulation Of Body Fluid Levels Retrograde Vesicle-mediated Transport, Golgi To ER Negative Regulation Of Nucleotide Metabolic Process Negative Regulation Of Calcium Ion Transport Vesicle Targeting Localization Within Membrane Regulation Of Phosphorylation Activation Of Phospholipase C Activity Intra-Golgi Vesicle-mediated Transport Regulation Of Protein Kinase Activity Positive Regulation Of Phospholipase C Activity
Tagcloud ?		ca037 ca530 cadd chlamydiaceae chlamydophila copd1 copd2 inca incc pkn5 psittaci scc1 scc2 scc3 sctc sctd sctj sctl sctn sctq sctr scts sctt sctu sctv sctw t3s t3ss tarp	102kspsklsp109 adenylyl anandamide anticipated arrestin1 beta3 cb1 conform contraction endowed engage erk1 galphai galphaq gbetagamma gi grk5 k215r minigene mlc myosin mypt1 ptx rhoa rip ser103 ser108 signaled uncoupling
Tagcloud (Difference) ?		ca037 ca530 cadd chlamydiaceae chlamydophila copd1 copd2 inca incc pkn5 psittaci scc1 scc2 scc3 sctc sctd sctj sctl sctn sctq sctr scts sctt sctu sctv sctw t3s t3ss tarp	102kspsklsp109 adenylyl anandamide anticipated arrestin1 beta3 cb1 conform contraction endowed engage erk1 galphai galphaq gbetagamma gi grk5 k215r minigene mlc myosin mypt1 ptx rhoa rip ser103 ser108 signaled uncoupling
Tagcloud (Intersection) ?