COPB1 and TMED10

Number of citations of the paper that reports this interaction (PMID 9751720)
22

Data Source:
BioGRID (pull down)

		COPB1	TMED10
Gene Name		coatomer protein complex, subunit beta 1	transmembrane emp24-like trafficking protein 10 (yeast)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Membrane COPI Vesicle Coat Intracellular Membrane-bounded Organelle	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Plasma Membrane Integral Component Of Membrane COPI-coated Vesicle Trans-Golgi Network Transport Vesicle Transport Vesicle Membrane Secretory Granule Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Zymogen Granule Membrane Extracellular Vesicular Exosome Gamma-secretase Complex
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding Syntaxin Binding Protein Complex Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Viral Process COPI Coating Of Golgi Vesicle Membrane Organization	Kidney Development Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Golgi Organization Cargo Loading Into Vesicle COPI-coated Vesicle Budding Response To Alkaloid Regulated Secretory Pathway Vesicle Targeting, To, From Or Within Golgi COPI Coating Of Golgi Vesicle COPII Vesicle Coating Protein Oligomerization Regulation Of Beta-amyloid Formation
Pathways		COPI Mediated Transport Golgi to ER Retrograde Transport
Drugs
Diseases
GWAS			Height ( 19343178)
Protein-Protein Interactions		32 interactors: ADAM19 APP ARCN1 ARF1 COPE COPG1 COPG2 ERBB2IP FOXB1 GRB2 HLA-DPB1 HLA-G ID1 IRAK3 KCNK3 KDELR1 LZTS2 NUB1 PDGFRB PRKCE RGS2 RGS4 RHOQ SERTAD1 SNTA1 TANK TAPBP TMED10 TRIM37 UBQLN4 VPS18 XRCC6	15 interactors: APH1A ARCN1 ARF1 COPA COPB1 COPB2 COPE COPG1 COPZ1 DHODH GORASP2 NCSTN PSENEN SEC23B TMED2
Entrez ID		1315	10972
HPRD ID		02981	12013
Ensembl ID		ENSG00000129083	ENSG00000170348
Uniprot IDs		P53618	B4DL12 P49755
PDB IDs
Enriched GO Terms of Interacting Partners?		Retrograde Vesicle-mediated Transport, Golgi To ER COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Vesicle Targeting Localization Within Membrane Intracellular Transport Golgi Vesicle Transport Membrane Budding Vesicle-mediated Transport Establishment Of Localization In Cell Innate Immune Response Cellular Localization Immune Response-regulating Signaling Pathway Regulation Of Cytoskeleton Organization Immune Response Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Immune System Process Regulation Of MAPK Cascade Regulation Of Actin Filament-based Process Regulation Of Organelle Organization Regulation Of Phosphorylation Defense Response Protein Transport Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Organelle Localization ERBB Signaling Pathway Regulation Of Protein Metabolic Process Establishment Of Protein Localization Regulation Of Phosphorus Metabolic Process Regulation Of Actin Cytoskeleton Organization Regulation Of Immune Response Protein Localization Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Intracellular Protein Transport Positive Regulation Of Immune Response Negative Regulation Of MAP Kinase Activity Transport Organelle Localization Regulation Of Phospholipase Activity Regulation Of Immune System Process Antigen Processing And Presentation Of Peptide Antigen Cellular Copper Ion Homeostasis Cellular Protein Localization Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation	COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting Retrograde Vesicle-mediated Transport, Golgi To ER Membrane Budding Golgi Vesicle Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Establishment Of Organelle Localization Organelle Localization Membrane Organization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Intracellular Protein Transport Protein Localization Intra-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Amyloid Precursor Protein Catabolic Process Membrane Protein Intracellular Domain Proteolysis Membrane Protein Ectodomain Proteolysis Amyloid Precursor Protein Metabolic Process Cellular Localization Notch Receptor Processing Cellular Protein Localization Membrane Protein Proteolysis Organelle Organization Transport Ephrin Receptor Signaling Pathway ER To Golgi Vesicle-mediated Transport Notch Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Protein Processing Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cerebellar Purkinje Cell Layer Maturation Apoptotic Signaling Pathway Axon Guidance Cerebellum Maturation 'de Novo' UMP Biosynthetic Process Body Fluid Secretion Axonogenesis Establishment Of Golgi Localization
Tagcloud ?		ca037 ca530 cadd chlamydiaceae chlamydophila copd1 copd2 inca incc pkn5 psittaci scc1 scc2 scc3 sctc sctd sctj sctl sctn sctq sctr scts sctt sctu sctv sctw t3s t3ss tarp	aiming aip alignment boar brms1 chordc1 clues cops6 csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmem70 y2h
Tagcloud (Difference) ?		ca037 ca530 cadd chlamydiaceae chlamydophila copd1 copd2 inca incc pkn5 psittaci scc1 scc2 scc3 sctc sctd sctj sctl sctn sctq sctr scts sctt sctu sctv sctw t3s t3ss tarp	aiming aip alignment boar brms1 chordc1 clues cops6 csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmem70 y2h
Tagcloud (Intersection) ?