XRCC6 and CHEK1

  • Number of citations of the paper that reports this interaction (PMID 12756247)
  • 14
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro, in vivo)

XRCC6

CHEK1

Gene Name X-ray repair complementing defective repair in Chinese hamster cells 6 checkpoint kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 126 interactors: ABCD4 ABL1 ACD ADCY7 ANXA1 APEX1 AR ARAP1 ATP6V1E1 BARD1 BAZ1A BTG1 CAPN11 CBX5 CCNA1 CCT3 CD40 CDCA5 CDK2 CDKN1A CEBPA CENPU CHAF1A CHEK1 CLTC CLU CMTM6 COIL COPB1 CREBBP CSNK2A1 CTBP2 DLX2 DNTT EFNA1 EGFR EID1 ELF3 EP300 EPS8 FMNL1 GAL3ST4 GSE1 GZMA GZMB H2AFX HERPUD1 HMGA2 HN1L HOXB7 HOXC4 HOXD4 HSF1 HTT ILVBL KAT2A KAT2B KIAA0408 LIG3 MAP2K5 MAP4K2 MAPK8 MRE11A MSX2 NAA15 NCF4 NCL NCOA6 NHP2L1 NIT1 NOTCH1 PAEP PAFAH1B3 PARP1 PCNA PDK1 PDPK1 PDX1 PECAM1 PGAM1 PGR PIN1 PLGRKT PNRC2 POR POU2F1 POU2F2 PRKDC PRPF40A PTTG1 QRSL1 RASA1 RBBP4 RGS2 RNF146 RPLP1 RPS10 RRAS2 RUNX2 SDHC SEP15 SERPINA2 SERPINB9 SGOL1 SIRT3 SKIL SMAD3 SMAD7 SNTA1 SPARC TAC1 TADA3 TBCD TCF4 TERF2 TERF2IP TERT TP53 VAV1 VBP1 WBP4 WRN XRCC5 XRCC6BP1 YWHAZ ZNF512B 37 interactors: AATF AKT1 APP ATM ATR BLM BRCA1 CDC25A CDC25B CDC25C CHUK CLSPN CSNK2B CUL1 CUL4A DTL FANCE HSP90AA1 LATS2 MCPH1 MDM4 PIGM PRKDC RAD51 RB1 RELA SMAD4 TIMELESS TLK1 TOPBP1 TP53 UBB USP7 XIAP XPO1 XRCC6 YWHAG
Entrez ID 2547 1111
HPRD ID 01071 04356
Ensembl ID ENSG00000196419 ENSG00000149554
Uniprot IDs B1AHC8 B1AHC9 P12956 B4DT73 O14757
PDB IDs 1JEQ 1JEY 1JJR 3RZX 1IA8 1NVQ 1NVR 1NVS 1ZLT 1ZYS 2AYP 2BR1 2BRB 2BRG 2BRH 2BRM 2BRN 2BRO 2C3J 2C3K 2C3L 2CGU 2CGV 2CGW 2CGX 2E9N 2E9O 2E9P 2E9U 2E9V 2GDO 2GHG 2HOG 2HXL 2HXQ 2HY0 2QHM 2QHN 2R0U 2WMQ 2WMR 2WMS 2WMT 2WMU 2WMV 2WMW 2WMX 2X8D 2X8E 2X8I 2XEY 2XEZ 2XF0 2YDI 2YDJ 2YDK 2YER 2YEX 2YM3 2YM4 2YM5 2YM6 2YM7 2YM8 2YWP 3F9N 3JVR 3JVS 3NLB 3OT3 3OT8 3PA3 3PA4 3PA5 3TKH 3TKI 3U9N 4FSM 4FSN 4FSQ 4FSR 4FST 4FSU 4FSW 4FSY 4FSZ 4FT0 4FT3 4FT5 4FT7 4FT9 4FTA 4FTC 4FTI 4FTJ 4FTK 4FTL 4FTM 4FTN 4FTO 4FTQ 4FTR 4FTT 4FTU 4GH2 4HYH 4HYI 4JIK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
brca2  cellularity  cg  chance  copyright  cytopenia  genesis  genotype  genotyped  gg  heterozygote  hypercellular  john  karyotype  lig4  ltd  normocellular  polymorphism  polymorphisms  rad51  rs1801320  rs1805388  rs2267437  rs3835  rs4793191  rs9567623  sons  wiley  xrcc5 
aggressive  atr  bcss  clinically  consequences  cytoplasmic  deregulated  doxycycline  knock  lymphovascular  mb  mcf10a  mcf7  mda  mitotic  personalized  phenotypes  pleomorphism  positivity  predictor  rational  restored  ser345  serine345  signalling  tumorigenic  univariate  ve 
Tagcloud (Difference) ?
brca2  cellularity  cg  chance  copyright  cytopenia  genesis  genotype  genotyped  gg  heterozygote  hypercellular  john  karyotype  lig4  ltd  normocellular  polymorphism  polymorphisms  rad51  rs1801320  rs1805388  rs2267437  rs3835  rs4793191  rs9567623  sons  wiley  xrcc5 
aggressive  atr  bcss  clinically  consequences  cytoplasmic  deregulated  doxycycline  knock  lymphovascular  mb  mcf10a  mcf7  mda  mitotic  personalized  phenotypes  pleomorphism  positivity  predictor  rational  restored  ser345  serine345  signalling  tumorigenic  univariate  ve 
Tagcloud (Intersection) ?