RICTOR and SIRT1

  • Number of citations of the paper that reports this interaction (PMID 22084251)
  • 5
  • Data Source:
  • BioGRID (enzymatic study)

RICTOR

SIRT1

Gene Name RPTOR independent companion of MTOR, complex 2 sirtuin 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 13 interactors: AKT1 AKT1S1 CHUK CUL1 EIF4EBP1 GSK3B HDAC1 IKBKB ILK MTOR RPS6KB1 SGK1 SIRT1 47 interactors: AKT1 ARNTL BCL11A BHLHE41 CDK6 CSNK2B CTTN EP300 ESRRA FOS FOXO1 FOXO3 GAPDH HES1 HEY2 HIC1 HIST1H1B HIST1H3A HNF4A IRS2 MAPK8 MAPT MYCN NBN NMNAT1 NR1H2 NR1H3 NR1H4 PARP1 PML PPARA PPARGC1A PSME3 RARA RELA RICTOR RRP8 SATB1 SETD7 SMAD7 SNW1 SREBF1 STK11 STK4 TP53 UBE2I VDR
Entrez ID 253260 23411
HPRD ID 10682 08381
Ensembl ID ENSG00000164327 ENSG00000096717
Uniprot IDs Q6R327 A8K128 B0QZ35 E9PC49 Q96EB6
PDB IDs 4I5I
Enriched GO Terms of Interacting Partners?
Tagcloud ?
70kda  ablation  amp  ampk  aortas  apoe  apolipoprotein  arg2  arginase  atherogenesis  atherosclerosis  atherosclerotic  autophagy  crosstalk  h160f  impairs  interested  mtorc1  mtorc2  nonsenescent  polypeptide  prkaa  replicative  rps6kb1  s6  s6k1  senescent  ureahydrolase  wk 
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
Tagcloud (Difference) ?
70kda  ablation  amp  ampk  aortas  apoe  apolipoprotein  arg2  arginase  atherogenesis  atherosclerosis  atherosclerotic  autophagy  crosstalk  h160f  impairs  interested  mtorc1  mtorc2  nonsenescent  polypeptide  prkaa  replicative  rps6kb1  s6  s6k1  senescent  ureahydrolase  wk 
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
Tagcloud (Intersection) ?