NEIL2 and MEOX1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NEIL2	MEOX1
Gene Name		nei endonuclease VIII-like 2 (E. coli)	mesenchyme homeobox 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Spindle Microtubule	Nucleus Cytoplasm
	Molecular Function	Damaged DNA Binding DNA-(apurinic Or Apyrimidinic Site) Lyase Activity Microtubule Binding Zinc Ion Binding Hydrolase Activity, Hydrolyzing N-glycosyl Compounds	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Molecular_function Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding HMG Box Domain Binding
	Biological Process	DNA Catabolic Process, Endonucleolytic Base-excision Repair Nucleotide-excision Repair	Somite Specification Transcription, DNA-templated Multicellular Organismal Development Biological_process Positive Regulation Of Transcription From RNA Polymerase II Promoter Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development
Pathways
Drugs
Diseases
GWAS		Neutrophil count ( 21507922)
Protein-Protein Interactions		4 interactors: EP300 MEOX1 REL TRIM27	28 interactors: ALOX5 APP APPL1 CIAO1 CIB3 CKS1B CWF19L2 CYFIP1 DCX FMR1 MAPK9 MID1 MORF4L1 MVP NAGK NEIL2 PAGE3 PARK2 PAX1 PAX3 QRICH1 RANBP3 SOX10 SYT17 TCEANC TXLNA UBE2R2 UBXN2B
Entrez ID		252969	4222
HPRD ID		16406	02537
Ensembl ID		ENSG00000154328	ENSG00000005102
Uniprot IDs		Q969S2	P50221
PDB IDs		1VZP
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cytokine Production Regulation Of Viral Transcription Immune System Process Somitogenesis Transcription, DNA-templated Somite Development RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Segmentation Innate Immune Response Histone H2B Acetylation Cytokine Production Regulation Of Viral Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-2 Secretion RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Expression Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity N-terminal Peptidyl-lysine Acetylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Sclerotome Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Immune Response Anterior/posterior Pattern Specification Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Defense Response Negative Regulation Of Biosynthetic Process Regulation Of Tubulin Deacetylation Negative Regulation Of Calcium Ion Import Somite Specification Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Cytokine Production Interferon-gamma Secretion Nucleobase-containing Compound Metabolic Process Positive Regulation By Host Of Viral Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process	Cell Proliferation Central Nervous System Development Developmental Cell Growth Developmental Growth Developmental Growth Involved In Morphogenesis Cell Growth Protein K48-linked Ubiquitination Protein Monoubiquitination Axon Extension Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Leukotriene Production Involved In Inflammatory Response Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Neural Crest Cell Migration Mesenchyme Development Growth Cellular Macromolecule Catabolic Process Regulation Of Protein Tyrosine Kinase Activity Nervous System Development Regulation Of Phosphorylation Base-excision Repair Neuron Projection Extension Synaptic Growth At Neuromuscular Junction Positive Regulation Of Protein Linear Polyubiquitination N-acetylmannosamine Metabolic Process Positive Regulation Of Transcription, DNA-templated Developmental Pigmentation Neural Crest Cell Development Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Proteasomal Protein Catabolic Process Protein Localization To Mitochondrion Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine Depurination Dopamine Uptake Involved In Synaptic Transmission Collateral Sprouting In Absence Of Injury Neural Crest Cell Differentiation Cognition Positive Regulation Of Proteolysis Regulation Of Phosphorus Metabolic Process
Tagcloud ?		acetylated acetylates acetylation ap arg base bases coactivator conserved discovered enzymes excision glycosylase inactivates inactivation interacts lyase lys153 lys49 modifications modulate orthologs oxidized recently repair reversible stably translational
Tagcloud (Difference) ?		acetylated acetylates acetylation ap arg base bases coactivator conserved discovered enzymes excision glycosylase inactivates inactivation interacts lyase lys153 lys49 modifications modulate orthologs oxidized recently repair reversible stably translational
Tagcloud (Intersection) ?