NEIL2

Gene Name		nei endonuclease VIII-like 2 (E. coli)
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Spindle Microtubule
	Molecular Function	Damaged DNA Binding DNA-(apurinic Or Apyrimidinic Site) Lyase Activity Microtubule Binding Zinc Ion Binding Hydrolase Activity, Hydrolyzing N-glycosyl Compounds
	Biological Process	DNA Catabolic Process, Endonucleolytic Base-excision Repair Nucleotide-excision Repair
Pathways
Drugs
Diseases
GWAS		Neutrophil count ( 21507922)
Protein-protein Interactions		4 interactors: EP300 MEOX1 REL TRIM27
Entrez ID		252969
HPRD ID		16406
Ensembl ID		ENSG00000154328
Uniprot IDs		Q969S2
PDB IDs		1VZP
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cytokine Production Regulation Of Viral Transcription Immune System Process Somitogenesis Transcription, DNA-templated Somite Development RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Segmentation Innate Immune Response Histone H2B Acetylation Cytokine Production Regulation Of Viral Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-2 Secretion RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Expression Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity N-terminal Peptidyl-lysine Acetylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Sclerotome Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Immune Response Anterior/posterior Pattern Specification Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Defense Response Negative Regulation Of Biosynthetic Process Regulation Of Tubulin Deacetylation Negative Regulation Of Calcium Ion Import Somite Specification Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Cytokine Production Interferon-gamma Secretion Nucleobase-containing Compound Metabolic Process Positive Regulation By Host Of Viral Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process
Tagcloud ?		acetylated acetylates acetylation ap arg base bases coactivator conserved discovered enzymes excision glycosylase inactivates inactivation interacts lyase lys153 lys49 modifications modulate orthologs oxidized recently repair reversible stably translational