NR5A1 and RAD54L2

Number of citations of the paper that reports this interaction (PMID 19692572)
9

Data Source:
BioGRID (pull down)

		NR5A1	RAD54L2
Gene Name		nuclear receptor subfamily 5, group A, member 1	RAD54-like 2 (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus
	Molecular Function	DNA Binding Chromatin Binding Double-stranded DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Transcription Coactivator Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Phospholipid Binding Zinc Ion Binding Enzyme Binding Sequence-specific DNA Binding	DNA Binding Transcription Cofactor Activity Helicase Activity ATP Binding Protein Kinase Binding
	Biological Process	Luteinization Transcription Initiation From RNA Polymerase II Promoter Cell-cell Signaling Primary Sex Determination Male Gonad Development Tissue Development Multicellular Organismal Aging Gene Expression Cell Differentiation Adrenal Gland Development Intracellular Receptor Signaling Pathway Hormone Metabolic Process Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Steroid Biosynthetic Process Maintenance Of Protein Location In Nucleus Positive Regulation Of Male Gonad Development Negative Regulation Of Female Gonad Development	Metabolic Process Regulation Of Nucleic Acid-templated Transcription
Pathways		Transcriptional regulation of pluripotent stem cells Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: AR CREBBP CTNNB1 CXXC1 EDF1 GATA4 GTF2B JUN MAPK1 NCK2 NCOA1 NFKB2 NFYA NR0B1 NRIP1 PIAS1 PITX1 PNRC2 PROX1 RAD54L2 SMARCD3 SOX2 SOX8 SOX9 SP1 TBX19 TRERF1 ZNF653	14 interactors: AR ATN1 ATXN1 ATXN1L NR3C1 NR5A1 NR5A2 PIAS1 PPARG PSMA3 RXRA SIAH1 SUMO1 UBE2I
Entrez ID		2516	23132
HPRD ID		01702	10018
Ensembl ID		ENSG00000136931	ENSG00000164080
Uniprot IDs		F1D8R8 Q13285	B3KV54 Q9Y4B4
PDB IDs		1YOW 1ZDT
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Gland Development Reproductive Structure Development Reproductive System Development Sex Differentiation Regulation Of Cell Differentiation Positive Regulation Of Cell Proliferation Regulation Of Cell Proliferation Developmental Process Involved In Reproduction Multicellular Organismal Development Androgen Receptor Signaling Pathway Cell Fate Commitment Embryonic Morphogenesis Male Sex Differentiation Rhythmic Process Cell Differentiation Organ Development Single Organism Reproductive Process Regulation Of Cellular Process Glial Cell Fate Commitment Camera-type Eye Morphogenesis Developmental Process Anatomical Structure Development	Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus DNA-templated Transcription, Initiation Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Cellular Response To Organic Cyclic Compound Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Response To Lipid RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Response To Steroid Hormone Gene Expression Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Protein Sumoylation Negative Regulation Of Cellular Metabolic Process Cellular Response To Hormone Stimulus Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process RNA Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Organic Substance Cellular Macromolecule Biosynthetic Process Reproductive Process Macromolecule Biosynthetic Process Peroxisome Proliferator Activated Receptor Signaling Pathway Response To Lipid Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process
Tagcloud ?		attracted bisphenol bpa durations esr estrogenic expressions flanking gobiocypris inhibitive involve minnow monomer mug nominal obviously oocyte ovarian ovary rarus reproduction researchers steroidogenesis steroidogenic stimulative subfamily suppressive vitellogenin vtg
Tagcloud (Difference) ?		attracted bisphenol bpa durations esr estrogenic expressions flanking gobiocypris inhibitive involve minnow monomer mug nominal obviously oocyte ovarian ovary rarus reproduction researchers steroidogenesis steroidogenic stimulative subfamily suppressive vitellogenin vtg
Tagcloud (Intersection) ?