SGK3 and SLC9A3R2

Number of citations of the paper that reports this interaction (PMID 11751930)
39

Data Source:
HPRD (in vitro)

		SGK3	SLC9A3R2
Gene Name		serum/glucocorticoid regulated kinase family, member 3	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Cytosol Cytoplasmic Membrane-bounded Vesicle Recycling Endosome	Nucleus Cytoplasm Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Calcium Channel Regulator Activity Protein Binding ATP Binding Potassium Channel Regulator Activity Sodium Channel Regulator Activity Chloride Channel Regulator Activity Phosphatidylinositol Binding	Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding
	Biological Process	Regulation Of Cell Growth Protein Phosphorylation Response To Stress Regulation Of Cell Migration Ion Transmembrane Transport Regulation Of Cell Proliferation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Transmembrane Transport	Protein Complex Assembly Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Pathways		Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: APP GSK3A GSK3B ITCH PDPK1 SLC9A3R2	35 interactors: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDPK1 PDZK1 PIK3CA PLCB3 PODXL PRKACA PTEN PTH1R RDX SGK1 SGK3 SIAH1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A WWTR1
Entrez ID		23678	9351
HPRD ID		06349	05946
Ensembl ID		ENSG00000104205	ENSG00000065054
Uniprot IDs		Q53EW6 Q5H9Q5 Q96BR1	Q15599
PDB IDs			2D11 2HE4 2OCS
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Type B Pancreatic Cell Development Hypermethylation Of CpG Island Innate Immune Response Cellular Response To Interleukin-3 Apoptotic Process Programmed Cell Death Negative Regulation Of Glycogen (starch) Synthase Activity Cell Death Death Negative Regulation Of Signal Transduction Negative Regulation Of Intracellular Signal Transduction Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Signaling Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Metabolic Process Negative Regulation Of Cardiac Muscle Hypertrophy Locomotion Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Muscle Hypertrophy Regulation Of Glycogen (starch) Synthase Activity Regulation Of Signal Transduction Immune Response Regulation Of Phosphorylation Defense Response Phosphatidylinositol-mediated Signaling Regulation Of Signaling Regulation Of Type B Pancreatic Cell Development Regulation Of Phosphorus Metabolic Process Positive Regulation Of Peptidyl-threonine Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Growth Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of DNA Methylation Regulation Of Intracellular Signal Transduction Regulation Of Protein Kinase Activity Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Protein Catabolic Process Neurotrophin Signaling Pathway Negative Regulation Of Catalytic Activity Fc-epsilon Receptor Signaling Pathway Regulation Of Kinase Activity Positive Regulation Of Intracellular Transport Regulation Of Gene Expression By Genetic Imprinting Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cardiac Muscle Hypertrophy Response To Lithium Ion Regulation Of Cellular Protein Metabolic Process	Regulation Of Protein Kinase Activity Ion Homeostasis Transmembrane Transport Regulation Of Kinase Activity Regulation Of Ion Transport Positive Regulation Of Ion Transport Regulation Of Protein Phosphorylation Homeostatic Process Positive Regulation Of Transport Ion Transport Regulation Of Phosphorus Metabolic Process Positive Regulation Of Transferase Activity Regulation Of Phosphorylation Ion Transmembrane Transport Cellular Cation Homeostasis Organic Anion Transport Cellular Ion Homeostasis Cytosolic Calcium Ion Homeostasis Chemical Homeostasis Positive Regulation Of Protein Kinase Activity Blood Circulation Positive Regulation Of Cellular Protein Metabolic Process Anion Transport Platelet Activation Positive Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Transport Positive Regulation Of Protein Phosphorylation Sodium-independent Organic Anion Transport Carnitine Transport Cellular Chemical Homeostasis Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Body Fluid Levels Monocarboxylic Acid Transport Sperm Capacitation Anion Transmembrane Transport Regulation Of Cellular Component Organization Sodium Ion Transport Inorganic Anion Transport Regulation Of Cellular Protein Metabolic Process Response To Organonitrogen Compound Regulation Of Ion Transmembrane Transport Blood Coagulation Hemostasis Activation Of Protein Kinase Activity Positive Regulation Of Phosphorylation Quaternary Ammonium Group Transport Positive Regulation Of Cytosolic Calcium Ion Concentration
Tagcloud ?		androgen ar confers depletion dht eralpha erbeta functionally functioning g1 glucocorticoid identifies inducible inhibiting isoforms lncap locus p70 p70s6k phosphatidylinositol pi3k promoters promotes prostate responsiveness s6 ser summary thr
Tagcloud (Difference) ?		androgen ar confers depletion dht eralpha erbeta functionally functioning g1 glucocorticoid identifies inducible inhibiting isoforms lncap locus p70 p70s6k phosphatidylinositol pi3k promoters promotes prostate responsiveness s6 ser summary thr
Tagcloud (Intersection) ?