ARL1 and GCC1

Number of citations of the paper that reports this interaction (PMID 12972563)
32

Data Source:
BioGRID (two hybrid)

		ARL1	GCC1
Gene Name		ADP-ribosylation factor-like 1	GRIP and coiled-coil domain containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Trans-Golgi Network Extracellular Vesicular Exosome	Golgi Membrane Cytoplasm Golgi Apparatus Plasma Membrane
	Molecular Function	GTPase Activity GTP Binding Enzyme Activator Activity Protein Domain Specific Binding Metal Ion Binding	Protein Binding
	Biological Process	Golgi Organization Small GTPase Mediated Signal Transduction Toxin Metabolic Process Activation Of Phospholipase D Activity Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport	Protein Targeting To Golgi
Pathways
Drugs
Diseases
GWAS			Type 2 diabetes ( 22158537)
Protein-Protein Interactions		7 interactors: ARFIP2 COPG2 GCC1 GCC2 GOLGA1 GOLGA4 SCOC	36 interactors: ABI2 AMOTL2 APP ARL1 ATF4 ATN1 BIRC2 BRCA1 C1orf94 CCDC85B CEP57 CEP70 COIL CPSF7 DNAJA3 FBF1 GLI1 GOLGA2 GTF2I IKBKG ITSN1 KIAA0753 KIAA1217 LZTS2 MCRS1 NAB2 NAV1 NECAB2 NINL OIP5 PAK7 SMARCD1 TFIP11 TRIM29 USHBP1 ZNF276
Entrez ID		400	79571
HPRD ID		04574	07599
Ensembl ID		ENSG00000120805	ENSG00000179562
Uniprot IDs		B4DZG7 P40616	A4D0Z4 Q96CN9
PDB IDs		1UPT 4DCN
Enriched GO Terms of Interacting Partners?		Intra-Golgi Vesicle-mediated Transport Protein Targeting To Golgi Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Protein Localization To Golgi Apparatus Golgi Vesicle Transport Establishment Of Protein Localization To Organelle Intracellular Protein Transport Protein Targeting Protein Localization To Organelle Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Cytoplasmic Transport Protein Localization Establishment Of Localization In Cell Cellular Localization Recycling Endosome To Golgi Transport Late Endosome To Golgi Transport Regulation Of Protein Exit From Endoplasmic Reticulum Golgi Ribbon Formation Protein Targeting To Lysosome Protein Localization To Lysosome Positive Regulation Of Macroautophagy Transport Endomembrane System Organization Protein Targeting To Vacuole Golgi To Plasma Membrane Protein Transport Establishment Of Protein Localization To Vacuole Golgi To Plasma Membrane Transport Positive Regulation Of Autophagy Retrograde Vesicle-mediated Transport, Golgi To ER Ruffle Organization Positive Regulation Of Axon Extension Lysosomal Transport Lamellipodium Assembly Lamellipodium Organization Microtubule Anchoring Retrograde Transport, Endosome To Golgi	Apoptotic Process Programmed Cell Death Cell Death Death Organelle Organization Transcription, DNA-templated RNA Metabolic Process Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Intracellular Signal Transduction Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Anatomical Structure Development Developmental Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Toxin Metabolic Process Negative Regulation Of Cell Death Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase III Promoter Nitrogen Compound Metabolic Process G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Ubiquitination Cell Communication Positive Regulation Vascular Endothelial Growth Factor Production Signal Transduction Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death System Development Multicellular Organismal Development Cellular Process NIK/NF-kappaB Signaling Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Biosynthetic Process Cell Cycle Positive Regulation Of Histone H4-K20 Methylation Spliceosomal Complex Disassembly Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Protein Monoubiquitination Positive Regulation Of Protein K48-linked Ubiquitination
Tagcloud ?		actb arfgap2 bestkeeper bmi1 casc3 cynomolgus ddx3x gapdh genorm lists monkey morf4 mrfap1 normalization normfinder ormdl1 prerequisite reference ribosylation rps19 rsl24d1 sar1a traditionally transcriptome usp22 vitally ywhaz zc3h11a zranb2
Tagcloud (Difference) ?		actb arfgap2 bestkeeper bmi1 casc3 cynomolgus ddx3x gapdh genorm lists monkey morf4 mrfap1 normalization normfinder ormdl1 prerequisite reference ribosylation rps19 rsl24d1 sar1a traditionally transcriptome usp22 vitally ywhaz zc3h11a zranb2
Tagcloud (Intersection) ?