TRPV1 and TRPV2

Number of citations of the paper that reports this interaction (PubMedID 16115206)
0

Data Source:
HPRD (in vivo)

		TRPV1	TRPV2
Description		transient receptor potential cation channel subfamily V member 1	transient receptor potential cation channel subfamily V member 2
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane Dendritic Spine Membrane Cell Projection Neuron Projection Synapse Postsynaptic Membrane GABA-ergic Synapse	Cytoplasm Plasma Membrane Cell Surface Membrane Axon Growth Cone Membrane Melanosome Axonal Growth Cone Cell Body
	Molecular Function	Nucleotide Binding Transmembrane Signaling Receptor Activity Monoatomic Ion Channel Activity Extracellular Ligand-gated Monoatomic Ion Channel Activity Excitatory Extracellular Ligand-gated Monoatomic Ion Channel Activity Voltage-gated Calcium Channel Activity Calcium Channel Activity Protein Binding Calmodulin Binding ATP Binding Intracellularly Gated Calcium Channel Activity Phosphatidylinositol Binding Metal Ion Binding Phosphoprotein Binding Temperature-gated Ion Channel Activity	Monoatomic Ion Channel Activity Monoatomic Cation Channel Activity Calcium Channel Activity Protein Binding Monoatomic Ion Transmembrane Transporter Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Temperature Homeostasis Fever Generation Diet Induced Thermogenesis Peptide Secretion Lipid Metabolic Process Monoatomic Ion Transport Calcium Ion Transport Cell Surface Receptor Signaling Pathway Chemosensory Behavior Response To PH Response To Heat Urinary Bladder Smooth Muscle Contraction Sensory Perception Of Pain Calcium-mediated Signaling Monoatomic Ion Transmembrane Transport Cellular Response To Heat Response To Pain Behavioral Response To Pain Sensory Perception Of Taste Sensory Perception Of Mechanical Stimulus Thermoception Detection Of Temperature Stimulus Involved In Thermoception Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Protein Homotetramerization Transmembrane Transport Excitatory Postsynaptic Potential Smooth Muscle Contraction Involved In Micturition Calcium Ion Transmembrane Transport Cellular Response To Alkaloid Cellular Response To ATP Cellular Response To Acidic PH Calcium Ion Import Across Plasma Membrane Response To Capsazepine Calcium Ion Import Into Cytosol	Monoatomic Ion Transport Calcium Ion Transport Sensory Perception Response To Temperature Stimulus Monoatomic Ion Transmembrane Transport Positive Regulation Of Axon Extension Transmembrane Transport Calcium Ion Transmembrane Transport Positive Regulation Of Calcium Ion Import Calcium Ion Import Across Plasma Membrane Positive Regulation Of Cold-induced Thermogenesis
Pathways		TRP channels	TRP channels
Drugs		alpha-Linolenic acid Icosapent Aspartame Tramadol Acetaminophen Camphor Ricinoleic acid Resiniferatoxin Capsaicin Cannabidiol Zucapsaicin Propacetamol Capsicum oleoresin Nonivamide (S)-camphor Medical Cannabis Nabiximols Cannabidivarin	Cannabidiol Tetrahydrocannabivarin Medical Cannabis Nabiximols Cannabidivarin
Diseases
GWAS			Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
Interacting Genes		8 interacting genes: AKAP5 CALM1 EGFR ITCH PRKCE SNAPIN SYT9 TRPV2	2 interacting genes: SLC50A1 TRPV1
Entrez ID		7442	51393
HPRD ID		03648	05980
Ensembl ID		ENSG00000196689	ENSG00000187688
Uniprot IDs		Q8NER1	Q9Y5S1
PDB IDs		6L93 8GF8 8GF9 8GFA 8JQR 8X94 8YCP	2F37
Enriched GO Terms of Interacting Partners?		Regulation Of Calcium Ion Transport Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Periphery Positive Regulation Of Protein Localization To Membrane Chemical Synaptic Transmission Regulation Of Metal Ion Transport Trans-synaptic Signaling Synaptic Signaling Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Transport Regulation Of Transport Synaptic Vesicle Membrane Regulation Of Monoatomic Ion Transport Regulation Of Calcium Ion Transmembrane Transport Positive Regulation Of Synaptic Transmission Regulation Of Protein Localization To Cell Periphery Modulation Of Chemical Synaptic Transmission Regulation Of Protein Localization To Membrane Positive Regulation Of Calcium Ion Import Calcineurin-mediated Signaling Regulation Of Cellular Localization Cell-cell Signaling Signaling Cell Communication Regulation Of Calcium Ion Import Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Cell Communication Regulation Of Signaling Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Cellular Component Organization Multivesicular Body, Internal Vesicle Lumen Positive Regulation Of Late Endosome To Lysosome Transport SNARE Binding Clathrin-coated Endocytic Vesicle Membrane Negative Regulation Of Cation Transmembrane Transport Positive Regulation Of Signal Transduction Intracellular Signaling Cassette Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Cell Communication Negative Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cytokinesis Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Vesicle-mediated Transport In Synapse Intracellular Signal Transduction Positive Regulation Of Signaling Regulation Of Calcium-mediated Signaling Regulation Of Cell Growth Shc-EGFR Complex Synapse	Temperature-gated Ion Channel Activity Response To Capsazepine Glucoside Transmembrane Transporter Activity Sugar Transmembrane Transporter Activity Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Fever Generation Smooth Muscle Contraction Involved In Micturition Glucoside Transport Thermoception Detection Of Temperature Stimulus Involved In Thermoception Excitatory Extracellular Ligand-gated Monoatomic Ion Channel Activity Sensory Perception Of Temperature Stimulus Urinary Bladder Smooth Muscle Contraction Heat Generation Intracellularly Gated Calcium Channel Activity Diet Induced Thermogenesis Dendritic Spine Membrane Cellular Response To ATP Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Behavioral Response To Pain Chemosensory Behavior Response To Pain Cellular Response To Acidic PH Detection Of Temperature Stimulus Calcium Ion Import Across Plasma Membrane Detection Of Temperature Stimulus Involved In Sensory Perception Calcium Ion Import Into Cytosol Adaptive Thermogenesis Response To Acidic PH Cellular Response To PH Sensory Perception Of Taste Cellular Response To Alkaloid Temperature Homeostasis Extracellular Ligand-gated Monoatomic Ion Channel Activity Response To ATP Voltage-gated Calcium Channel Activity Transmembrane Transport Calcium Ion Import Hexose Transmembrane Transport Phosphoprotein Binding Response To PH Acute-phase Response Sensory Perception Of Pain Carbohydrate Transmembrane Transport Carbohydrate Transport Cellular Response To Heat Smooth Muscle Contraction Protein Homotetramerization Excitatory Postsynaptic Potential Acute Inflammatory Response
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