RBM17 and MIR128-1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		RBM17	MIR128-1
Description		RNA binding motif protein 17	microRNA 128-1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Protein-containing Complex	Extracellular Space RISC Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	RNA Splicing, Via Transesterification Reactions Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing MRNA Cis Splicing, Via Spliceosome	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Gene Expression Negative Regulation Of Lipoprotein Particle Clearance Negative Regulation Of Cell Migration MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Cholesterol Homeostasis Positive Regulation Of Cell Adhesion Lipid Homeostasis Cellular Response To Lipopolysaccharide Negative Regulation Of Cholesterol Efflux Negative Regulation Of Lipoprotein Transport Negative Regulation Of Macrophage Colony-stimulating Factor Production Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Brown Fat Cell Differentiation Negative Regulation Of Macrophage Migration
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474 31959851) Asthma and hay fever ( 24388013) Asthma or allergic disease (pleiotropy) ( 29785011) Brooding (response to stress) ( 30886212) Crohn's disease ( 28067908) Diisocyanate-induced asthma ( 25918132) Multiple sclerosis ( 24076602) Soluble interleukin-2 receptor subunit alpha ( 26293465) Vitiligo ( 20410501)	Body mass index ( 26426971)
Interacting Genes		33 interacting genes: APBB1 C6orf47 CCDC170 CCHCR1 CEBPA CEP55 CSNK2A1 CWC15 FAM9B GOLGA2 HINFP HSF2BP IQCN LNX2 MIR106B MIR107 MIR128-1 MIR155 MIR21 MIR25 MIRLET7A2 MIRLET7G MIRLET7I OGT PPP1R12C PRC1 QRICH1 RBFOX2 SAP30BP SAT1 SF1 SF3B1 TNS3	91 interacting genes: AIMP1 AIMP2 APOBEC3B ATXN2 ATXN2L C1QBP CASC3 CELF1 CPSF6 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC LSM10 LSM11 MARS1 MATR3 MSI2 NOL6 NONO NUDT16L1 NUFIP2 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 PURA PURB QARS1 RARS1 RBFOX2 RBM10 RBM12B RBM14 RBM17 RBM4 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 USP36 UTP20 YBX1 YBX2 YBX3 ZFR
Entrez ID		84991	406915
HPRD ID		09501
Ensembl ID		ENSG00000134453	ENSG00000207654
Uniprot IDs		Q5W009 Q96I25
PDB IDs		2PE8 2PEH 5LSO 6HIP
Enriched GO Terms of Interacting Partners?		RISC Complex MRNA Base-pairing Post-transcriptional Repressor Activity MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Translation MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Metabolic Process Regulation Of Translation Extracellular Vesicle Regulation Of Rac Protein Signal Transduction Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Protein Metabolic Process Regulation Of Fat Cell Differentiation Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Gene Expression MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Cytokine Production Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Cell Cycle Regulation Of Macromolecule Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Catabolic Process Sin3-type Complex Negative Regulation Of Developmental Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Negative Regulation Of Multicellular Organismal Process Regulation Of Protein Metabolic Process Negative Regulation Of Protein Catabolic Process Spermidine Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Necroptotic Process U11/U12 SnRNP Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Lipoprotein Transport Cellular Response To Resveratrol Negative Regulation Of Hydrogen Sulfide Biosynthetic Process Negative Regulation Of Endothelial Tube Morphogenesis Positive Regulation Of Replicative Senescence Negative Regulation Of Aortic Smooth Muscle Cell Differentiation	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process Ribonucleoprotein Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Post-transcriptional Regulation Of Gene Expression Nucleus Aminoacyl-tRNA Synthetase Multienzyme Complex Cytoplasmic Stress Granule Nucleoplasm Spliceosomal Complex Regulation Of Translation Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Metabolic Process Catalytic Step 2 Spliceosome Negative Regulation Of RNA Catabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Regulation Of Primary Metabolic Process MRNA 3'-UTR Binding Regulation Of Macromolecule Metabolic Process MiRNA Binding Negative Regulation Of MRNA Catabolic Process RNA Stabilization MRNA Stabilization Negative Regulation Of Metabolic Process Regulation Of Metabolic Process Regulation Of RNA Stability Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Gene Expression RNA Transport TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of MRNA Stability TRNA Aminoacylation Nucleolus Negative Regulation Of Gene Expression
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