AGTPBP1 and RSPH1

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		AGTPBP1	RSPH1
Description		ATP/GTP binding carboxypeptidase 1	radial spoke head component 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Plasma Membrane Cilium Microtubule Cytoskeleton Axon Centriolar Satellite Ciliary Basal Body Axon Cytoplasm	Condensed Nuclear Chromosome Outer Dense Fiber Radial Spoke Radial Spoke Head Nucleus Chromosome Cytoplasm Cytosol Cytoskeleton Cilium Axoneme Motile Cilium Sperm Flagellum Cell Projection Meiotic Spindle 9+2 Motile Cilium Radial Spoke Head 1 Radial Spoke Head 3
	Molecular Function	Carboxypeptidase Activity Metallocarboxypeptidase Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Tubulin Binding Hydrolase Activity Metal Ion Binding	Protein Binding
	Biological Process	Eye Photoreceptor Cell Differentiation Proteolysis Mitochondrion Organization Adult Walking Behavior Negative Regulation Of Cell Population Proliferation Cerebellum Development Cerebellar Purkinje Cell Layer Development Cerebellar Purkinje Cell Differentiation Olfactory Bulb Development Central Nervous System Neuron Development Protein Deglutamylation C-terminal Protein Deglutamylation Protein Side Chain Deglutamylation Neuromuscular Process Retina Development In Camera-type Eye Axonal Transport Anterograde Axonal Transport Of Mitochondrion Retrograde Axonal Transport Of Mitochondrion Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process	Microtubule-based Process Spermatid Development Axoneme Assembly Meiotic Cell Cycle
Pathways		Carboxyterminal post-translational modifications of tubulin
Drugs
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258)
Interacting Genes		13 interacting genes: CBY1 CYCS DISC1 ENO1 NYNRIN PPFIA1 PPFIA4 PYGM RSPH1 RUNX1 TNIK UBC VPS26C	125 interacting genes: ABCA2 AGTPBP1 APPL1 ASCL1 B4GALT3 BTBD1 BTG3 CADM1 CASK CCN2 CFH CLSTN3 CLU CMAS CNPPD1 COG4 CORO1C CORO2A CORO2B CREBZF CRMP1 CTSL CTTN CXXC5 DCTN6 DEF8 DNAJC7 DNER DOCK3 DST EDIL3 EEF2 EIF3D EZR FAIM FLOT1 FN1 FRMD4B GAMT GLS GLUL HIVEP2 JPH1 JPH3 KDM4A KDM6A KIF1A KIF1B LGI3 LONRF1 MAPK8IP1 MAPK8IP2 MBD4 MEG3 MFGE8 MIA2 MKRN3 MORN2 MORN3 MTMR2 MYCBP2 NCAM2 NELL1 NETO1 NF2 NFKBID NHP2 NPRL2 NRCAM OAT OBSL1 OSBPL1A PARP1 PAX6 PDE4DIP PLEC PNMA2 POGZ POLR2C PTPRD RARB RELN RHOG RNF10 SDHA SEPTIN3 SEZ6L SF1 SF3B1 SH3GLB2 SMARCE1 SNRNP70 SOX10 SRXN1 TF TOLLIP TRIM33 TRIM52 TUBA1B TUBB TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B UAP1L1 UBA7 UBC USP11 USP7 USP9X USP9Y WBP11 WDR13 WDR17 ZBTB38 ZBTB44 ZBTB5 ZNF197 ZNF251 ZNF34 ZNF512B ZNF662 ZNF785 ZNF793
Entrez ID		23287	89765
HPRD ID		08442	11651
Ensembl ID		ENSG00000135049	ENSG00000160188
Uniprot IDs		J3KNS1 Q9UPW5	Q8WYR4
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?			Microtubule Cytoskeleton Structural Constituent Of Cytoskeleton Co-SMAD Binding Cytoskeleton Cell Periphery Neuron Migration Cell-substrate Junction Organization Cell-substrate Junction Assembly Retrograde Axonal Transport Negative Regulation Of Schwann Cell Proliferation Microtubule Cytoskeleton Organization Nucleus Positive Regulation Of Early Endosome To Late Endosome Transport Axon Intercellular Bridge Microtubule-based Process Mitotic Cell Cycle Regulation Of Nervous System Development Axon Cytoplasm Axonal Transport GTPase Activity Regulation Of Cell Projection Organization Cell Junction Organization Microtubule Regulation Of Plasma Membrane Bounded Cell Projection Organization Cytoskeleton Organization Oligodendrocyte Cell Fate Specification Anterograde Axonal Transport Chromaffin Granule Regulation Of Early Endosome To Late Endosome Transport Negative Regulation Of Glial Cell Proliferation Regulation Of Nervous System Process Regulation Of Myelination GTP Binding Axo-dendritic Transport Regulation Of Synapse Organization Cerebral Cortex Development Regulation Of Cell Morphogenesis Synapse Modulation Of Excitatory Postsynaptic Potential Retrograde Neuronal Dense Core Vesicle Transport Mitotic Spindle Positive Regulation Of Cell Differentiation Regulation Of Postsynapse Organization Cell Motility Dendrite Cytoskeleton-dependent Intracellular Transport Regulation Of Cellular Component Organization Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Hemidesmosome Assembly
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