RSPH1 and CADM1

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		RSPH1	CADM1
Description		radial spoke head component 1	cell adhesion molecule 1
Image
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Outer Dense Fiber Radial Spoke Radial Spoke Head Nucleus Chromosome Cytoplasm Cytosol Cytoskeleton Cilium Axoneme Motile Cilium Sperm Flagellum Cell Projection Meiotic Spindle 9+2 Motile Cilium Radial Spoke Head 1 Radial Spoke Head 3	Plasma Membrane Cell-cell Junction Membrane Basolateral Plasma Membrane Neuron Projection Synapse
	Molecular Function	Protein Binding	Signaling Receptor Binding Protein Binding PDZ Domain Binding Protein Homodimerization Activity
	Biological Process	Microtubule-based Process Spermatid Development Axoneme Assembly Meiotic Cell Cycle	Positive Regulation Of Cytokine Production T Cell Mediated Cytotoxicity Immune System Process Apoptotic Process Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Spermatogenesis Cell Recognition Cell Differentiation Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Activated T Cell Proliferation Detection Of Stimulus
Pathways			Adherens junctions interactions Nectin/Necl trans heterodimerization
Drugs
Diseases			Nasopharyngeal cancer
GWAS			Adult body size ( 32376654) Anorexia nervosa ( 31308545) Body mass index ( 25673413 31978080 28892062 28552196) Body size at age 10 ( 32376654) Cardiovascular risk factors (age interaction) ( 20838585) Childhood body mass index ( 33045005) Chronotype ( 30696823) Coffee consumption ( 31046077) Cutaneous squamous cell carcinoma ( 27424798 32041948) Diastolic blood pressure ( 34074324) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Heel bone mineral density ( 28869591 30598549) Left-handedness ( 32989287) Menarche (age at onset) ( 27182965 25231870) Obesity-related traits ( 23251661) Serum linoleic acid concentration in metabolic syndrome ( 31991592) Systolic blood pressure ( 34074324) Thyroid stimulating hormone levels ( 32769997 30367059) Type 2 diabetes (age of onset) ( 28060188) Waist circumference ( 28552196)
Interacting Genes		125 interacting genes: ABCA2 AGTPBP1 APPL1 ASCL1 B4GALT3 BTBD1 BTG3 CADM1 CASK CCN2 CFH CLSTN3 CLU CMAS CNPPD1 COG4 CORO1C CORO2A CORO2B CREBZF CRMP1 CTSL CTTN CXXC5 DCTN6 DEF8 DNAJC7 DNER DOCK3 DST EDIL3 EEF2 EIF3D EZR FAIM FLOT1 FN1 FRMD4B GAMT GLS GLUL HIVEP2 JPH1 JPH3 KDM4A KDM6A KIF1A KIF1B LGI3 LONRF1 MAPK8IP1 MAPK8IP2 MBD4 MEG3 MFGE8 MIA2 MKRN3 MORN2 MORN3 MTMR2 MYCBP2 NCAM2 NELL1 NETO1 NF2 NFKBID NHP2 NPRL2 NRCAM OAT OBSL1 OSBPL1A PARP1 PAX6 PDE4DIP PLEC PNMA2 POGZ POLR2C PTPRD RARB RELN RHOG RNF10 SDHA SEPTIN3 SEZ6L SF1 SF3B1 SH3GLB2 SMARCE1 SNRNP70 SOX10 SRXN1 TF TOLLIP TRIM33 TRIM52 TUBA1B TUBB TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B UAP1L1 UBA7 UBC USP11 USP7 USP9X USP9Y WBP11 WDR13 WDR17 ZBTB38 ZBTB44 ZBTB5 ZNF197 ZNF251 ZNF34 ZNF512B ZNF662 ZNF785 ZNF793	8 interacting genes: ATF7IP CASK DNAJC5 EPB41L3 MPP3 PSMA6 RSPH1 SDCBP
Entrez ID		89765	23705
HPRD ID		11651	05746
Ensembl ID		ENSG00000160188	ENSG00000182985
Uniprot IDs		Q8WYR4	A0A4Z1 Q9BY67 X5D7A8 X5D8W0 X5DQR8 X5DQS5
PDB IDs		8J07	3BIN 4H5S
Enriched GO Terms of Interacting Partners?		Microtubule Cytoskeleton Structural Constituent Of Cytoskeleton Co-SMAD Binding Cytoskeleton Cell Periphery Neuron Migration Cell-substrate Junction Organization Cell-substrate Junction Assembly Retrograde Axonal Transport Negative Regulation Of Schwann Cell Proliferation Microtubule Cytoskeleton Organization Nucleus Positive Regulation Of Early Endosome To Late Endosome Transport Axon Intercellular Bridge Microtubule-based Process Mitotic Cell Cycle Regulation Of Nervous System Development Axon Cytoplasm Axonal Transport GTPase Activity Regulation Of Cell Projection Organization Cell Junction Organization Microtubule Regulation Of Plasma Membrane Bounded Cell Projection Organization Cytoskeleton Organization Oligodendrocyte Cell Fate Specification Anterograde Axonal Transport Chromaffin Granule Regulation Of Early Endosome To Late Endosome Transport Negative Regulation Of Glial Cell Proliferation Regulation Of Nervous System Process Regulation Of Myelination GTP Binding Axo-dendritic Transport Regulation Of Synapse Organization Cerebral Cortex Development Regulation Of Cell Morphogenesis Synapse Modulation Of Excitatory Postsynaptic Potential Retrograde Neuronal Dense Core Vesicle Transport Mitotic Spindle Positive Regulation Of Cell Differentiation Regulation Of Postsynapse Organization Cell Motility Dendrite Cytoskeleton-dependent Intracellular Transport Regulation Of Cellular Component Organization Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Hemidesmosome Assembly
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?