AGTPBP1 and PPFIA4

Number of citations of the paper that reports this interaction (PubMedID 16713569)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		AGTPBP1	PPFIA4
Description		ATP/GTP binding carboxypeptidase 1	PPFI scaffold protein A4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Plasma Membrane Cilium Microtubule Cytoskeleton Axon Centriolar Satellite Ciliary Basal Body Axon Cytoplasm	Cytoplasm Cytosol Cell Surface Synapse Presynaptic Active Zone
	Molecular Function	Carboxypeptidase Activity Metallocarboxypeptidase Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Tubulin Binding Hydrolase Activity Metal Ion Binding	Protein Binding
	Biological Process	Eye Photoreceptor Cell Differentiation Proteolysis Mitochondrion Organization Adult Walking Behavior Negative Regulation Of Cell Population Proliferation Cerebellum Development Cerebellar Purkinje Cell Layer Development Cerebellar Purkinje Cell Differentiation Olfactory Bulb Development Central Nervous System Neuron Development Protein Deglutamylation C-terminal Protein Deglutamylation Protein Side Chain Deglutamylation Neuromuscular Process Retina Development In Camera-type Eye Axonal Transport Anterograde Axonal Transport Of Mitochondrion Retrograde Axonal Transport Of Mitochondrion Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process	Synapse Organization
Pathways		Carboxyterminal post-translational modifications of tubulin	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258)	Asthma ( 31959851) Asthma (childhood onset) ( 31036433) Atrial fibrillation ( 28416822 29892015 30061737) Early onset atrial fibrillation ( 28460022)
Interacting Genes		13 interacting genes: CBY1 CYCS DISC1 ENO1 NYNRIN PPFIA1 PPFIA4 PYGM RSPH1 RUNX1 TNIK UBC VPS26C	6 interacting genes: AGTPBP1 CAST DNAJC5 ERC2 GIT1 NCOA2
Entrez ID		23287	8497
HPRD ID		08442	16012
Ensembl ID		ENSG00000135049	ENSG00000143847
Uniprot IDs		J3KNS1 Q9UPW5	A0A8J8YUZ5 B3KN22 B4DIS5 O75335
PDB IDs
Enriched GO Terms of Interacting Partners?			Presynaptic Active Zone Organization Locomotory Behavior Maintenance Of Synapse Structure Presynapse Cell Junction Maintenance Cellular Component Maintenance Calcium-dependent Cysteine-type Endopeptidase Inhibitor Activity Negative Regulation Of ARF Protein Signal Transduction Anterograde Axonal Transport Of Mitochondrion GABA-ergic Synapse Regulation Of Calcium-dependent Activation Of Synaptic Vesicle Fusion Regulation Of Vesicle-mediated Transport Structural Constituent Of Postsynaptic Specialization Cellular Response To Thyroglobulin Triiodothyronine Retrograde Axonal Transport Of Mitochondrion C-terminal Protein Deglutamylation Growth Cone Protein Deglutamylation Protein Side Chain Deglutamylation Neuron Development Response To Thyroglobulin Triiodothyronine Negative Regulation Of Type B Pancreatic Cell Apoptotic Process RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding Aryl Hydrocarbon Receptor Binding Structural Constituent Of Presynaptic Active Zone Maintenance Of Presynaptic Active Zone Structure Intramembranous Ossification Positive Regulation Of Microtubule Nucleation Motor Learning ATP-dependent Protein Binding Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Chromaffin Granule Membrane Synapse Organization Positive Regulation Of Receptor Catabolic Process Maintenance Of Postsynaptic Specialization Structure Negative Regulation Of Inflammatory Response To Wounding Cytoplasm Locomotor Rhythm Peroxisome Proliferator Activated Receptor Signaling Pathway Regulation Of Small Molecule Metabolic Process Positive Regulation Of Adipose Tissue Development Peptidyl-glutamic Acid Modification Cerebellar Purkinje Cell Layer Development Axonal Transport Of Mitochondrion Cerebellar Purkinje Cell Differentiation Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Presynaptic Active Zone Cytoplasmic Component Immunological Synapse Formation Dendritic Spine Development Regulation Of Inflammatory Response To Wounding
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