MTUS2 and CBX8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MTUS2	CBX8
Gene Name		microtubule associated tumor suppressor candidate 2	chromobox homolog 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Cytoplasmic Microtubule	Nuclear Chromatin Heterochromatin Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Protein Binding Microtubule Binding Protein Homodimerization Activity	Single-stranded RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Methylated Histone Binding
	Biological Process		Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Histone Ubiquitination
Pathways			Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS		Insomnia (caffeine-induced) ( 22754043) Obesity-related traits ( 23251661)
Protein-Protein Interactions		167 interactors: AEN AES AFF4 ALS2CR11 AQP1 ARNT2 BMP7 BYSL C14orf105 C19orf66 C1orf109 C1orf216 C20orf195 C21orf58 C8orf34 CATIP CATSPER1 CBX8 CCDC116 CCDC146 CCDC17 CCDC60 CCHCR1 CDC20B CDC73 CDK18 CDK5R1 CDKL3 CEP57L1 CEP95 CERK COG2 CREB5 CRY2 CTSZ CWF19L2 CXCL11 CXCL16 DCDC2B DCTN4 DLGAP5 DMRT3 DOCK2 DTNB FAM13C FAM161A FAM71E2 FAM74A4 FAM90A1 FBXL18 FBXO34 FCHSD2 GAL3ST2 GOLGA2P11 GTF2I GTPBP10 HAUS1 HCK HDAC4 HSF2 IQCE ITGB5 ITSN1 KAT5 KIF1A LENG1 LIMS2 LINC00636 LMO2 LNX1 LOC153684 LRR1 LYSMD1 MAGEA8 MARK4 MFAP1 MTMR6 NDEL1 NDOR1 NELFE NUBPL NUDT10 ODF1 PDE4DIP PIN1 PKP2 PLK4 PLSCR4 POLDIP2 POLDIP3 PPHLN1 PPP1R18 PRKAA1 PRPF31 PSMA1 PTPMT1 RAB3IL1 RGS2 RHPN1 RIBC2 ROBO3 RPA1 RPL9 RTP5 SCEL SDCBP SELM SETD5 SH2D4A SH3RF2 SLC23A1 SLC25A6 SLIRP SMARCE1 SNAI1 SNHG11 SNRPA SNRPB2 SNW1 SPATA8 SPG7 STK16 SYT6 TAF13 THAP7 TP53RK TRIM42 TSGA10IP TSHZ3 TXN2 USP2 WAC WDYHV1 ZBTB38 ZC2HC1C ZFC3H1 ZFP2 ZFP64 ZFYVE21 ZMAT2 ZNF136 ZNF20 ZNF224 ZNF232 ZNF250 ZNF3 ZNF329 ZNF337 ZNF410 ZNF415 ZNF417 ZNF426 ZNF439 ZNF440 ZNF490 ZNF572 ZNF581 ZNF587 ZNF599 ZNF607 ZNF624 ZNF655 ZNF670 ZNF785 ZNF844 ZSCAN12 ZSCAN26	42 interactors: BMI1 CALCOCO2 CCDC136 CCDC57 EEF1G FSD2 GOLGA2 GPRASP2 HAP1 HIST3H3 HMBOX1 IKZF1 KAT5 KAT7 KCTD9 KIFC3 KRT40 LZTS2 MID2 MLLT1 MLLT3 MTUS2 PAXIP1 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 PHC2 PNMA2 RING1 RNF2 RPGRIP1 SETDB1 SOX5 TFCP2 TRAF2 TSGA10 UNC119 USP11 USP7 ZBTB14
Entrez ID		23281	57332
HPRD ID		11108	13006
Ensembl ID
Uniprot IDs		J3KQA9 Q5JR59	Q9HC52
PDB IDs			3I91
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Metabolic Process Cellular Process Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression Mitochondrion Morphogenesis Histone Ubiquitination T Cell Chemotaxis Histone H2B Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Tight Junction Assembly Cellular Response To Lipid Axon Cargo Transport Viral Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Positive Regulation Of Gene Expression Transepithelial Transport Signal Transduction By P53 Class Mediator Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Lymphocyte Chemotaxis Regulation Of Cell Cycle Process Negative Regulation Of Phosphatase Activity T Cell Migration	Transcription, DNA-templated RNA Biosynthetic Process Histone Modification Chromatin Modification Chromosome Organization Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone Ubiquitination Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Biosynthetic Process Histone H2A Monoubiquitination Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Histone H2A Ubiquitination Peptidyl-lysine Modification Regulation Of Metabolic Process Histone Monoubiquitination Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein Ubiquitination Organelle Organization Histone Acetylation Protein Modification By Small Protein Conjugation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Monoubiquitination Anterior/posterior Pattern Specification Protein Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Segment Specification Cellular Protein Modification Process Cellular Response To Reactive Oxygen Species
Tagcloud ?			aims approaches beings blotting causes chromobox colon conclude cultured express facilitating hct116 homolog igf1 igf1r knockdown leading line overexpression pathogenesis proliferation promote promoting real reports rt silencing unclear western
Tagcloud (Difference) ?			aims approaches beings blotting causes chromobox colon conclude cultured express facilitating hct116 homolog igf1 igf1r knockdown leading line overexpression pathogenesis proliferation promote promoting real reports rt silencing unclear western
Tagcloud (Intersection) ?