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MTUS2 and RPA1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
MTUS2
RPA1
Gene Name
microtubule associated tumor suppressor candidate 2
replication protein A1, 70kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Centrosome
Cytoplasmic Microtubule
Lateral Element
Male Germ Cell Nucleus
Nucleus
Nucleoplasm
DNA Replication Factor A Complex
PML Body
Molecular Function
Protein Binding
Microtubule Binding
Protein Homodimerization Activity
Chromatin Binding
Damaged DNA Binding
Single-stranded DNA Binding
Protein Binding
Metal Ion Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Nucleotide-excision Repair, DNA Damage Removal
Telomere Maintenance Via Recombination
Telomere Maintenance
Double-strand Break Repair Via Homologous Recombination
DNA Recombinase Assembly
In Utero Embryonic Development
DNA Replication
DNA-dependent DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Base-excision Repair
Nucleotide-excision Repair
Nucleotide-excision Repair, DNA Gap Filling
Mismatch Repair
Double-strand Break Repair
DNA Recombination
Meiotic Nuclear Division
Positive Regulation Of Cell Proliferation
Hemopoiesis
Telomere Maintenance Via Semi-conservative Replication
Cellular Response To Heat
Homeostasis Of Number Of Cells Within A Tissue
Regulation Of Cellular Response To Heat
Pathways
HSF1 activation
Gap-filling DNA repair synthesis and ligation in TC-NER
G2/M Checkpoints
Repair synthesis for gap-filling by DNA polymerase in TC-NER
Activation of the pre-replicative complex
DNA strand elongation
Mismatch Repair
G1/S Transition
Homologous recombination repair of replication-independent double-strand breaks
Mitotic G1-G1/S phases
Removal of the Flap Intermediate from the C-strand
Chromosome Maintenance
DNA Replication Pre-Initiation
S Phase
Removal of the Flap Intermediate
Global Genomic NER (GG-NER)
Nucleotide Excision Repair
Activation of the pre-replicative complex
Extension of Telomeres
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Assembly of the RAD51-ssDNA nucleoprotein complex
Telomere Maintenance
Activation of ATR in response to replication stress
Processing of DNA double-strand break ends
Double-Strand Break Repair
Dual incision reaction in GG-NER
Meiotic recombination
Synthesis of DNA
Lagging Strand Synthesis
Processive synthesis on the C-strand of the telomere
Processive synthesis on the lagging strand
M/G1 Transition
Cellular response to heat stress
Regulation of HSF1-mediated heat shock response
Telomere C-strand (Lagging Strand) Synthesis
Presynaptic phase of homologous DNA pairing and strand exchange
Repair synthesis of patch ~27-30 bases long by DNA polymerase
Cell Cycle, Mitotic
Gap-filling DNA repair synthesis and ligation in GG-NER
Homologous DNA pairing and strand exchange
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Transcription-coupled NER (TC-NER)
Homologous Recombination Repair
Formation of incision complex in GG-NER
Cell Cycle Checkpoints
Drugs
Diseases
GWAS
Insomnia (caffeine-induced) (
22754043
)
Obesity-related traits (
23251661
)
Protein-Protein Interactions
167 interactors:
AEN
AES
AFF4
ALS2CR11
AQP1
ARNT2
BMP7
BYSL
C14orf105
C19orf66
C1orf109
C1orf216
C20orf195
C21orf58
C8orf34
CATIP
CATSPER1
CBX8
CCDC116
CCDC146
CCDC17
CCDC60
CCHCR1
CDC20B
CDC73
CDK18
CDK5R1
CDKL3
CEP57L1
CEP95
CERK
COG2
CREB5
CRY2
CTSZ
CWF19L2
CXCL11
CXCL16
DCDC2B
DCTN4
DLGAP5
DMRT3
DOCK2
DTNB
FAM13C
FAM161A
FAM71E2
FAM74A4
FAM90A1
FBXL18
FBXO34
FCHSD2
GAL3ST2
GOLGA2P11
GTF2I
GTPBP10
HAUS1
HCK
HDAC4
HSF2
IQCE
ITGB5
ITSN1
KAT5
KIF1A
LENG1
LIMS2
LINC00636
LMO2
LNX1
LOC153684
LRR1
LYSMD1
MAGEA8
MARK4
MFAP1
MTMR6
NDEL1
NDOR1
NELFE
NUBPL
NUDT10
ODF1
PDE4DIP
PIN1
PKP2
PLK4
PLSCR4
POLDIP2
POLDIP3
PPHLN1
PPP1R18
PRKAA1
PRPF31
PSMA1
PTPMT1
RAB3IL1
RGS2
RHPN1
RIBC2
ROBO3
RPA1
RPL9
RTP5
SCEL
SDCBP
SELM
SETD5
SH2D4A
SH3RF2
SLC23A1
SLC25A6
SLIRP
SMARCE1
SNAI1
SNHG11
SNRPA
SNRPB2
SNW1
SPATA8
SPG7
STK16
SYT6
TAF13
THAP7
TP53RK
TRIM42
TSGA10IP
TSHZ3
TXN2
USP2
WAC
WDYHV1
ZBTB38
ZC2HC1C
ZFC3H1
ZFP2
ZFP64
ZFYVE21
ZMAT2
ZNF136
ZNF20
ZNF224
ZNF232
ZNF250
ZNF3
ZNF329
ZNF337
ZNF410
ZNF415
ZNF417
ZNF426
ZNF439
ZNF440
ZNF490
ZNF572
ZNF581
ZNF587
ZNF599
ZNF607
ZNF624
ZNF655
ZNF670
ZNF785
ZNF844
ZSCAN12
ZSCAN26
63 interactors:
AICDA
AKTIP
ANXA1
ANXA7
ASCC2
ATM
ATRIP
BID
BLM
BRCA2
BRIP1
CCNA1
CCNA2
CCNB1
CDC5L
CDK1
CDK2
CPE
CSNK2B
DMC1
EXO5
GNB5
HAX1
HELB
HGH1
HNRNPUL1
HUS1
MCM2
MCM4
MCM6
MCM7
MSH4
MTUS2
MUTYH
ORC2
ORC6
PAXIP1
PCNA
POLL
PRKDC
PRPF19
RAD1
RAD23B
RAD51
RAD52
RAD9A
RBM23
RCC1
RECQL
RPA2
RPA3
RPA4
RPS6KA5
SELENBP1
SMAD3
TCEA2
TK1
TP53
TREX1
VIM
WRN
XPA
XPC
Entrez ID
23281
6117
HPRD ID
11108
01565
Ensembl ID
ENSG00000132383
Uniprot IDs
J3KQA9
Q5JR59
P27694
PDB IDs
1EWI
1FGU
1JMC
1L1O
2B29
2B3G
4IJH
4IJL
4IPC
4IPD
4IPG
4IPH
Enriched GO Terms of Interacting Partners
?
RNA Biosynthetic Process
Transcription, DNA-templated
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Cellular Metabolic Process
Cellular Process
Regulation Of Cellular Process
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Metabolic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Gene Expression
Mitochondrion Morphogenesis
Histone Ubiquitination
T Cell Chemotaxis
Histone H2B Ubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Tight Junction Assembly
Cellular Response To Lipid
Axon Cargo Transport
Viral Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Developmental Process
Positive Regulation Of Gene Expression
Transepithelial Transport
Signal Transduction By P53 Class Mediator
Positive Regulation Of Cellular Metabolic Process
Regulation Of Cell Cycle
Lymphocyte Chemotaxis
Regulation Of Cell Cycle Process
Negative Regulation Of Phosphatase Activity
T Cell Migration
DNA Metabolic Process
Cellular Response To DNA Damage Stimulus
DNA Repair
DNA Replication
Cellular Response To Stress
Cell Cycle Process
Cell Cycle
DNA Damage Checkpoint
Nucleobase-containing Compound Metabolic Process
DNA-dependent DNA Replication
Cellular Nitrogen Compound Metabolic Process
DNA Recombination
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Chromosome Organization
Cell Cycle Checkpoint
Nitrogen Compound Metabolic Process
Mitotic Cell Cycle
Mitotic Cell Cycle Process
G1/S Transition Of Mitotic Cell Cycle
Regulation Of Mitotic Cell Cycle
Response To Stress
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
DNA Duplex Unwinding
DNA Geometric Change
Double-strand Break Repair
Regulation Of Cell Cycle
Response To Ionizing Radiation
DNA Conformation Change
Nucleotide-excision Repair
Mitotic DNA Damage Checkpoint
Organelle Organization
DNA Catabolic Process
Regulation Of Cell Cycle Process
Mitotic DNA Integrity Checkpoint
Response To Radiation
Mitotic Cell Cycle Checkpoint
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Cell Cycle
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
Regulation Of Cell Cycle Phase Transition
DNA Strand Elongation Involved In DNA Replication
Cellular Response To Stimulus
Response To Abiotic Stimulus
DNA Strand Elongation
Signal Transduction In Response To DNA Damage
Cellular Response To Ionizing Radiation
Cellular Macromolecule Biosynthetic Process
Tagcloud
?
200a
arthroplasty
backgroundischemia
conclusionsin
david
deeper
degs
downloaded
gabp
geo
insults
inverted
ipc
kegg
limma
mark0
mark1
meanwhile
methodsgse21164
mir141
omnibus
package
ppi
preconditioning
reperfused
resultssignificantly
string
t0
t1
Tagcloud (Difference)
?
200a
arthroplasty
backgroundischemia
conclusionsin
david
deeper
degs
downloaded
gabp
geo
insults
inverted
ipc
kegg
limma
mark0
mark1
meanwhile
methodsgse21164
mir141
omnibus
package
ppi
preconditioning
reperfused
resultssignificantly
string
t0
t1
Tagcloud (Intersection)
?