MTUS2 and DMRT3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MTUS2	DMRT3
Gene Name		microtubule associated tumor suppressor candidate 2	doublesex and mab-3 related transcription factor 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Cytoplasmic Microtubule	Nucleus
	Molecular Function	Protein Binding Microtubule Binding Protein Homodimerization Activity	Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process		Transcription, DNA-templated Regulation Of Transcription, DNA-templated Sex Differentiation Adult Walking Behavior Transmission Of Nerve Impulse Ventral Spinal Cord Interneuron Specification Regulation Of Odontogenesis Of Dentin-containing Tooth Male Sex Differentiation
Pathways
Drugs
Diseases
GWAS		Insomnia (caffeine-induced) ( 22754043) Obesity-related traits ( 23251661)	Major depressive disorder ( 23377640)
Protein-Protein Interactions		167 interactors: AEN AES AFF4 ALS2CR11 AQP1 ARNT2 BMP7 BYSL C14orf105 C19orf66 C1orf109 C1orf216 C20orf195 C21orf58 C8orf34 CATIP CATSPER1 CBX8 CCDC116 CCDC146 CCDC17 CCDC60 CCHCR1 CDC20B CDC73 CDK18 CDK5R1 CDKL3 CEP57L1 CEP95 CERK COG2 CREB5 CRY2 CTSZ CWF19L2 CXCL11 CXCL16 DCDC2B DCTN4 DLGAP5 DMRT3 DOCK2 DTNB FAM13C FAM161A FAM71E2 FAM74A4 FAM90A1 FBXL18 FBXO34 FCHSD2 GAL3ST2 GOLGA2P11 GTF2I GTPBP10 HAUS1 HCK HDAC4 HSF2 IQCE ITGB5 ITSN1 KAT5 KIF1A LENG1 LIMS2 LINC00636 LMO2 LNX1 LOC153684 LRR1 LYSMD1 MAGEA8 MARK4 MFAP1 MTMR6 NDEL1 NDOR1 NELFE NUBPL NUDT10 ODF1 PDE4DIP PIN1 PKP2 PLK4 PLSCR4 POLDIP2 POLDIP3 PPHLN1 PPP1R18 PRKAA1 PRPF31 PSMA1 PTPMT1 RAB3IL1 RGS2 RHPN1 RIBC2 ROBO3 RPA1 RPL9 RTP5 SCEL SDCBP SELM SETD5 SH2D4A SH3RF2 SLC23A1 SLC25A6 SLIRP SMARCE1 SNAI1 SNHG11 SNRPA SNRPB2 SNW1 SPATA8 SPG7 STK16 SYT6 TAF13 THAP7 TP53RK TRIM42 TSGA10IP TSHZ3 TXN2 USP2 WAC WDYHV1 ZBTB38 ZC2HC1C ZFC3H1 ZFP2 ZFP64 ZFYVE21 ZMAT2 ZNF136 ZNF20 ZNF224 ZNF232 ZNF250 ZNF3 ZNF329 ZNF337 ZNF410 ZNF415 ZNF417 ZNF426 ZNF439 ZNF440 ZNF490 ZNF572 ZNF581 ZNF587 ZNF599 ZNF607 ZNF624 ZNF655 ZNF670 ZNF785 ZNF844 ZSCAN12 ZSCAN26	26 interactors: CCNDBP1 INCA1 KHDRBS3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP5-9 MDFI MGAT5B MID2 MTUS2 NOTCH2NL PLSCR1 PSMA3 RBPMS REL SAT1 TCF4 TRAF1 TRIM23 TRIM27 TRIP6 UBASH3B
Entrez ID		23281	58524
HPRD ID		11108	16827
Ensembl ID			ENSG00000064218
Uniprot IDs		J3KQA9 Q5JR59	Q9NQL9
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Metabolic Process Cellular Process Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression Mitochondrion Morphogenesis Histone Ubiquitination T Cell Chemotaxis Histone H2B Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Tight Junction Assembly Cellular Response To Lipid Axon Cargo Transport Viral Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Positive Regulation Of Gene Expression Transepithelial Transport Signal Transduction By P53 Class Mediator Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Lymphocyte Chemotaxis Regulation Of Cell Cycle Process Negative Regulation Of Phosphatase Activity T Cell Migration	Positive Regulation Of Signal Transduction Regulation Of Intracellular Transport Regulation Of Signal Transduction Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Viral Process Regulation Of Intracellular Protein Transport Regulation Of Signaling Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Transferase Activity Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Protein Transport Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Localization Negative Regulation Of Viral Transcription Negative Regulation Of Cellular Metabolic Process Regulation Of Viral Release From Host Cell Regulation Of Establishment Of Protein Localization Regulation Of Protein Metabolic Process Regulation Of Viral Process Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Regulation Of Protein Localization Regulation Of Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Localization To Nucleus Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Protein Kinase Activity Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Kinase Activity Positive Regulation Of Intracellular Transport Regulation Of Transcription, DNA-templated I-kappaB Kinase/NF-kappaB Signaling Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Protein Ubiquitination Regulation Of Cellular Process Regulation Of RNA Metabolic Process Protein Modification By Small Protein Conjugation Regulation Of Protein Phosphorylation Regulation Of Viral Transcription Spermidine Acetylation Negative Regulation Of Interleukin-2 Secretion Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process Regulation Of Wnt Signaling Pathway
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