FLNC and MYOZ1

Number of citations of the paper that reports this interaction (PMID 10984498)
27

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		FLNC	MYOZ1
Gene Name		filamin C, gamma	myozenin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Sarcoplasm Z Disc Sarcolemma Costamere	Nucleus Actin Cytoskeleton Pseudopodium
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Ankyrin Binding Actin Filament Binding	Protein Binding FATZ Binding
	Biological Process	Cell Junction Assembly Muscle Fiber Development	Myofibril Assembly
Pathways		Cell junction organization Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: ADRA1A ADRA1B ADRA1D CAPN3 FURIN HIPK3 INPPL1 KCND2 KY MAP2K4 MYOT MYOZ1 MYOZ2 MYOZ3 NPHP1 PHLDB2 PRKAB2 PRKCA RPS6KA2 SGCD SGCG SYNPO2 TRIM54 TRIM55 TRIM63 USP25 WNK1 XIRP1 XIRP2	13 interactors: ACTN1 ACTN2 ACTN4 APP BRCA1 FLNC LDB3 MAGEA11 PNKP PRKAA2 TCAP TRIM55 TRIM63
Entrez ID		2318	58529
HPRD ID		00018	05725
Ensembl ID		ENSG00000128591	ENSG00000177791
Uniprot IDs		Q14315 Q59H94	B4DUK4 Q9NP98
PDB IDs		1V05 2D7M 2D7N 2D7O 2D7P 2D7Q 2K9U 2NQC 3V8O
Enriched GO Terms of Interacting Partners?		Neurological System Process Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Muscle Cell Development Blood Circulation Muscle Structure Development Heart Development Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Blood Pressure Cardiovascular System Development Positive Regulation Of Systemic Arterial Blood Pressure Adrenergic Receptor Signaling Pathway Muscle Cell Differentiation Regulation Of Blood Pressure Negative Regulation Of The Force Of Heart Contraction Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Cardiac Muscle Tissue Development Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine Organ Development Multicellular Organismal Development Developmental Process Regulation Of The Force Of Heart Contraction Vasoconstriction Positive Regulation Of The Force Of Heart Contraction By Chemical Signal Muscle Organ Development Positive Regulation Of Heart Rate By Epinephrine-norepinephrine Peptidyl-threonine Phosphorylation Striated Muscle Tissue Development Striated Muscle Cell Development System Development Muscle Tissue Development Regulation Of Heart Contraction Anatomical Structure Development Actin Cytoskeleton Organization Regulation Of The Force Of Heart Contraction By Chemical Signal Heart Contraction Actin Filament-based Process Myofibril Assembly Cell Development Regulation Of Blood Vessel Size Cellular Response To Carbohydrate Stimulus Regulation Of Tube Size Striated Muscle Cell Differentiation Adult Heart Development Muscle System Process Signaling Organ Growth Actomyosin Structure Organization Cell Communication Positive Regulation Of Heart Rate Peptidyl-serine Phosphorylation See more	Platelet Degranulation Protein Localization To Tight Junction Platelet Activation Cell Junction Assembly Protein Localization To Cell Junction Response To Abiotic Stimulus Actin Filament-based Process Cellular Component Assembly Exocytosis Actin Crosslink Formation Blood Coagulation Hemostasis Response To Stress Striated Muscle Cell Development Muscle Cell Development Secretion By Cell Actin-myosin Filament Sliding Focal Adhesion Assembly Muscle Filament Sliding Intracellular Receptor Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Cytoskeleton Organization Cell-cell Junction Organization Regulation Of Body Fluid Levels Muscle Contraction Actin Cytoskeleton Organization Wound Healing Striated Muscle Cell Differentiation Secretion Actin-mediated Cell Contraction Tight Junction Assembly Adherens Junction Assembly Muscle System Process Cell Activation Muscle Fiber Development Response To Wounding Positive Regulation Of Ion Transmembrane Transporter Activity Cell-substrate Junction Assembly Sarcomere Organization Positive Regulation Of Transporter Activity Actin Filament Organization Actin Filament Bundle Assembly Actin Filament-based Movement Regulation Of Apoptotic Process Muscle Cell Differentiation Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Apical Junction Assembly Regulation Of Cell Death Positive Regulation Of Ion Transmembrane Transport See more
Tagcloud ?		adh6 aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic	adapt calcineurin calsarcin calsarcins changing demands disc distances enable fast fiber fibers ko modulates muscles myoblasts myopathic myozenin nfat organism overt rcan1 running sarcomeric skeletal slow striated tightly twitch
Tagcloud (Difference) ?		adh6 aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic	adapt calcineurin calsarcin calsarcins changing demands disc distances enable fast fiber fibers ko modulates muscles myoblasts myopathic myozenin nfat organism overt rcan1 running sarcomeric skeletal slow striated tightly twitch
Tagcloud (Intersection) ?