FLNC and MYOZ3

Number of citations of the paper that reports this interaction (PMID 11842093)
29

Data Source:
HPRD (in vivo, in vitro)

		FLNC	MYOZ3
Gene Name		filamin C, gamma	myozenin 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Sarcoplasm Z Disc Sarcolemma Costamere	Z Disc
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Ankyrin Binding Actin Filament Binding	Protein Binding
	Biological Process	Cell Junction Assembly Muscle Fiber Development
Pathways		Cell junction organization Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: ADRA1A ADRA1B ADRA1D CAPN3 FURIN HIPK3 INPPL1 KCND2 KY MAP2K4 MYOT MYOZ1 MYOZ2 MYOZ3 NPHP1 PHLDB2 PRKAB2 PRKCA RPS6KA2 SGCD SGCG SYNPO2 TRIM54 TRIM55 TRIM63 USP25 WNK1 XIRP1 XIRP2	8 interactors: ACTN1 ACTN2 FLNC LDB3 MAPK6 PPP3CA PPP3CB TCAP
Entrez ID		2318	91977
HPRD ID		00018	17624
Ensembl ID		ENSG00000128591	ENSG00000164591
Uniprot IDs		Q14315 Q59H94	Q8TDC0
PDB IDs		1V05 2D7M 2D7N 2D7O 2D7P 2D7Q 2K9U 2NQC 3V8O
Enriched GO Terms of Interacting Partners?		Neurological System Process Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Muscle Cell Development Blood Circulation Muscle Structure Development Heart Development Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Blood Pressure Cardiovascular System Development Positive Regulation Of Systemic Arterial Blood Pressure Adrenergic Receptor Signaling Pathway Muscle Cell Differentiation Regulation Of Blood Pressure Negative Regulation Of The Force Of Heart Contraction Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Cardiac Muscle Tissue Development Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine Organ Development Multicellular Organismal Development Developmental Process Regulation Of The Force Of Heart Contraction Vasoconstriction Positive Regulation Of The Force Of Heart Contraction By Chemical Signal Muscle Organ Development Positive Regulation Of Heart Rate By Epinephrine-norepinephrine Peptidyl-threonine Phosphorylation Striated Muscle Tissue Development Striated Muscle Cell Development System Development Muscle Tissue Development Regulation Of Heart Contraction Anatomical Structure Development Actin Cytoskeleton Organization Regulation Of The Force Of Heart Contraction By Chemical Signal Heart Contraction Actin Filament-based Process Myofibril Assembly Cell Development Regulation Of Blood Vessel Size Cellular Response To Carbohydrate Stimulus Regulation Of Tube Size Striated Muscle Cell Differentiation Adult Heart Development Muscle System Process Signaling Organ Growth Actomyosin Structure Organization Cell Communication Positive Regulation Of Heart Rate Peptidyl-serine Phosphorylation	Striated Muscle Cell Development Muscle Cell Development Muscle Fiber Development Striated Muscle Cell Differentiation Calcineurin-NFAT Signaling Cascade Muscle Cell Differentiation Positive Regulation Of NFAT Protein Import Into Nucleus Inositol Phosphate-mediated Signaling Muscle Structure Development Cell Junction Assembly Actin Filament-based Process Cell Activation Actin-myosin Filament Sliding Focal Adhesion Assembly Muscle Filament Sliding Positive Regulation Of Transcription Factor Import Into Nucleus Actin-mediated Cell Contraction Adherens Junction Assembly Cell Development Cell-substrate Junction Assembly Sarcomere Organization Cellular Component Assembly Exocytosis Cellular Response To Drug Actin Filament-based Movement Platelet Degranulation Myofibril Assembly Transition Between Fast And Slow Fiber Cell Adhesion Adherens Junction Organization Regulation Of Transcription Factor Import Into Nucleus Calcium-mediated Signaling Positive Regulation Of Protein Import Into Nucleus Secretion By Cell Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Actomyosin Structure Organization Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Actin Cytoskeleton Organization Second-messenger-mediated Signaling Secretion Sarcomerogenesis Detection Of Muscle Stretch Skeletal Muscle Myosin Thick Filament Assembly Positive Regulation Of Intracellular Protein Transport Protein Localization To Tight Junction Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Regulation Of Protein Import Into Nucleus Cell-matrix Adhesion Positive Regulation Of Transport
Tagcloud ?		adh6 aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Difference) ?		adh6 aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Intersection) ?