FLNC and SYNPO2

Number of citations of the paper that reports this interaction (PMID 20554076)
8

Data Source:
BioGRID (two hybrid, pull down)

		FLNC	SYNPO2
Gene Name		filamin C, gamma	synaptopodin 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Sarcoplasm Z Disc Sarcolemma Costamere	Nucleus Focal Adhesion Actin Cytoskeleton Z Disc
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Ankyrin Binding Actin Filament Binding	Actin Binding Protein Binding Muscle Alpha-actinin Binding 14-3-3 Protein Binding
	Biological Process	Cell Junction Assembly Muscle Fiber Development
Pathways		Cell junction organization Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: ADRA1A ADRA1B ADRA1D CAPN3 FURIN HIPK3 INPPL1 KCND2 KY MAP2K4 MYOT MYOZ1 MYOZ2 MYOZ3 NPHP1 PHLDB2 PRKAB2 PRKCA RPS6KA2 SGCD SGCG SYNPO2 TRIM54 TRIM55 TRIM63 USP25 WNK1 XIRP1 XIRP2	6 interactors: ACTN2 CDK6 FLNA FLNC YWHAG YWHAZ
Entrez ID		2318	171024
HPRD ID		00018	15456
Ensembl ID		ENSG00000128591	ENSG00000172403
Uniprot IDs		Q14315 Q59H94	Q9UMS6
PDB IDs		1V05 2D7M 2D7N 2D7O 2D7P 2D7Q 2K9U 2NQC 3V8O
Enriched GO Terms of Interacting Partners?		Neurological System Process Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Muscle Cell Development Blood Circulation Muscle Structure Development Heart Development Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Blood Pressure Cardiovascular System Development Positive Regulation Of Systemic Arterial Blood Pressure Adrenergic Receptor Signaling Pathway Muscle Cell Differentiation Regulation Of Blood Pressure Negative Regulation Of The Force Of Heart Contraction Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Cardiac Muscle Tissue Development Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine Organ Development Multicellular Organismal Development Developmental Process Regulation Of The Force Of Heart Contraction Vasoconstriction Positive Regulation Of The Force Of Heart Contraction By Chemical Signal Muscle Organ Development Positive Regulation Of Heart Rate By Epinephrine-norepinephrine Peptidyl-threonine Phosphorylation Striated Muscle Tissue Development Striated Muscle Cell Development System Development Muscle Tissue Development Regulation Of Heart Contraction Anatomical Structure Development Actin Cytoskeleton Organization Regulation Of The Force Of Heart Contraction By Chemical Signal Heart Contraction Actin Filament-based Process Myofibril Assembly Cell Development Regulation Of Blood Vessel Size Cellular Response To Carbohydrate Stimulus Regulation Of Tube Size Striated Muscle Cell Differentiation Adult Heart Development Muscle System Process Signaling Organ Growth Actomyosin Structure Organization Cell Communication Positive Regulation Of Heart Rate Peptidyl-serine Phosphorylation	Cell Activation Platelet Activation Cell Junction Assembly Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Transport Regulation Of Protein Localization Positive Regulation Of Intracellular Transport Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cellular Localization Exocytosis Positive Regulation Of Mitochondrion Organization Blood Coagulation Hemostasis Regulation Of Intracellular Transport Platelet Degranulation Secretion By Cell Regulation Of Mitochondrion Organization Cell Dedifferentiation Regulation Of Body Fluid Levels Wound Healing Secretion Regulation Of Establishment Of Protein Localization Mitotic Cell Cycle Process Response To Wounding Cellular Component Assembly Mitotic Cell Cycle Establishment Of Localization In Cell Membrane Organization Intrinsic Apoptotic Signaling Pathway Golgi Reassembly Positive Regulation Of Apoptotic Signaling Pathway Cellular Localization Histamine Secretion By Mast Cell Microspike Assembly Cell Cycle Process Establishment Of Golgi Localization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Golgi Inheritance Negative Regulation Of Protein Localization To Cell Surface Cell Projection Assembly Cell Adhesion Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Negative Regulation Of Cellular Senescence Histamine Secretion Regulation Of Signal Transduction Stem Cell Differentiation Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Signal Transduction
Tagcloud ?		adh6 aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Difference) ?		adh6 aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Intersection) ?