MCF2L2 and MEGF10

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		MCF2L2	MEGF10
Description		MCF.2 cell line derived transforming sequence-like 2	multiple EGF like domains 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Phagocytic Cup Plasma Membrane Membrane Cell Projection
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity	Complement Component C1q Complex Binding Scavenger Receptor Activity Notch Binding
	Biological Process		Phagocytosis Cell Adhesion Muscle Organ Development Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Vesicle-mediated Transport Positive Regulation Of Cell-cell Adhesion Muscle Cell Proliferation Homotypic Cell-cell Adhesion Apoptotic Cell Clearance Engulfment Of Apoptotic Cell Recognition Of Apoptotic Cell Cell Development Myoblast Development Regulation Of Skeletal Muscle Tissue Development Regulation Of Muscle Cell Differentiation Myoblast Migration Muscle Cell Development Apoptotic Process Involved In Development Positive Regulation Of Myoblast Proliferation
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) QT interval ( 29213071) Subjective response to lithium treatment ( 26503763)	Alzheimer's disease (cognitive decline) ( 23535033) Appendicular lean mass ( 33097823) Bone mineral content ( 31790847) Chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183) Hearing loss in Charcot-Marie-Tooth disease 1A ( 30958311) Initial pursuit acceleration ( 29064472) Response to antipsychotic treatment in schizophrenia ( 29503163)
Interacting Genes		2 interacting genes: MEGF10 OLIG2	24 interacting genes: AARS2 ALMS1 AP2M1 ARHGAP32 BAHD1 CADPS2 CEP57 CUL7 DHX16 GRB10 GULP1 HDAC4 ITSN2 MCF2L2 RANBP10 SART3 SCAPER SHANK3 SHTN1 SNRNP200 TAOK2 TMEM132A VWA8 ZNFX1
Entrez ID		23101	84466
HPRD ID		08308	14384
Ensembl ID		ENSG00000053524	ENSG00000145794
Uniprot IDs		Q86YR7	Q96KG7
PDB IDs
Enriched GO Terms of Interacting Partners?		Spinal Cord Oligodendrocyte Cell Differentiation Oligodendrocyte Cell Fate Specification Glial Cell Fate Specification Spinal Cord Oligodendrocyte Cell Fate Specification Engulfment Of Apoptotic Cell Recognition Of Apoptotic Cell Skeletal Muscle Satellite Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Complement Component C1q Complex Binding Myoblast Development Skeletal Muscle Satellite Cell Activation HMG Box Domain Binding Thalamus Development Skeletal Muscle Cell Proliferation Phagocytosis, Recognition Myoblast Migration Positive Regulation Of Myoblast Proliferation Spinal Cord Motor Neuron Differentiation Positive Regulation Of Oligodendrocyte Differentiation Regulation Of Skeletal Muscle Tissue Development Regulation Of Myoblast Proliferation Scavenger Receptor Activity Notch Binding Apoptotic Cell Clearance Phagocytic Cup Muscle Cell Migration Phagocytosis, Engulfment Cell Differentiation In Spinal Cord Neuron Fate Commitment Positive Regulation Of Glial Cell Differentiation Regulation Of Oligodendrocyte Differentiation Apoptotic Process Involved In Development Oligodendrocyte Differentiation Muscle Cell Proliferation Regulation Of Striated Muscle Tissue Development Regulation Of Muscle Organ Development Membrane Invagination Axon Development E-box Binding Animal Organ Development Skeletal Muscle Cell Differentiation Positive Regulation Of Gliogenesis Homotypic Cell-cell Adhesion Regulation Of Glial Cell Differentiation Regulation Of Cell Differentiation Negative Regulation Of Neuron Differentiation Cell Fate Specification Myelination Axon Ensheathment Muscle Cell Development	Cytoplasm
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