MCF2L2 and MEGF10

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		MCF2L2	MEGF10
Gene Name		MCF.2 cell line derived transforming sequence-like 2	multiple EGF-like-domains 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Phagocytic Cup Integral Component Of Membrane Basolateral Plasma Membrane Cell Projection
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Positive Regulation Of Rho GTPase Activity	Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Homotypic Cell-cell Adhesion Recognition Of Apoptotic Cell Regulation Of Skeletal Muscle Tissue Development Regulation Of Muscle Cell Differentiation Muscle Cell Development
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease (cognitive decline) ( 23535033)
Protein-Protein Interactions		1 interactors: MEGF10	22 interactors: AARS2 ALMS1 AP2M1 ARHGAP32 BAHD1 CADPS2 CEP57 CUL7 DHX16 GRB10 HDAC4 ITSN2 KIAA1598 MCF2L2 RANBP10 SART3 SCAPER SNRNP200 TAOK2 TMEM132A VWA8 ZNFX1
Entrez ID		23101	84466
HPRD ID		08308	14384
Ensembl ID		ENSG00000053524	ENSG00000145794
Uniprot IDs		Q86YR7	Q96KG7
PDB IDs
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Satellite Cell Proliferation Skeletal Muscle Satellite Cell Activation Skeletal Muscle Cell Proliferation Skeletal Muscle Satellite Cell Differentiation Recognition Of Apoptotic Cell Phagocytosis, Recognition Apoptotic Cell Clearance Skeletal Muscle Cell Differentiation Regulation Of Skeletal Muscle Tissue Development Cell Recognition Regulation Of Striated Muscle Tissue Development Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Regulation Of Muscle Cell Differentiation Muscle Cell Development Phagocytosis Muscle Organ Development Striated Muscle Tissue Development Muscle Cell Differentiation Homotypic Cell-cell Adhesion Muscle Tissue Development Muscle Structure Development Single Organismal Cell-cell Adhesion	Organelle Organization Cellular Component Assembly Positive Regulation Of Metabolic Process MRNA Splicing, Via Spliceosome Positive Regulation Of Histone Deubiquitination Mitochondrial Alanyl-tRNA Aminoacylation RNA Splicing, Via Transesterification Reactions Positive Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity Cellular Macromolecular Complex Assembly Regulation Of Generation Of Precursor Metabolites And Energy Cis Assembly Of Pre-catalytic Spliceosome
Tagcloud ?			adhere adopt ap2 ap50 associating autoimmunity ced cerebellum clathrin clearing coated colocalized corpses deeper dishes elucidating engulfment flat immunoblot irregular mirrored mosaic nematode ortholog pits stellate ubiquitinated unusually vacuoles
Tagcloud (Difference) ?			adhere adopt ap2 ap50 associating autoimmunity ced cerebellum clathrin clearing coated colocalized corpses deeper dishes elucidating engulfment flat immunoblot irregular mirrored mosaic nematode ortholog pits stellate ubiquitinated unusually vacuoles
Tagcloud (Intersection) ?