MCF2L2 and OLIG2

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		MCF2L2	OLIG2
Description		MCF.2 cell line derived transforming sequence-like 2	oligodendrocyte transcription factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Chromatin Nucleus Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Protein Dimerization Activity E-box Binding HMG Box Domain Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Nervous System Development Sensory Organ Development Spinal Cord Motor Neuron Differentiation Spinal Cord Oligodendrocyte Cell Differentiation Spinal Cord Oligodendrocyte Cell Fate Specification Oligodendrocyte Cell Fate Specification Thalamus Development Central Nervous System Neuron Differentiation Neuron Differentiation Myelination Negative Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Commitment Oligodendrocyte Differentiation Positive Regulation Of Oligodendrocyte Differentiation Axon Development
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) QT interval ( 29213071) Subjective response to lithium treatment ( 26503763)	Bulimia nervosa ( 23568457) Caffeine consumption from tea ( 33287642) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 31527586) Tea consumption ( 31046077)
Interacting Genes		2 interacting genes: MEGF10 OLIG2	16 interacting genes: CKAP5 CUL3 EP300 EXOC7 GOLGA3 HEY1 KRTAP12-4 LRRFIP1 MCF2L2 MRFAP1L1 NAP1L2 NKX2-2 PSMA3 SOX10 SOX8 TXLNA
Entrez ID		23101	10215
HPRD ID		08308	07334
Ensembl ID		ENSG00000053524	ENSG00000205927
Uniprot IDs		Q86YR7	Q13516
PDB IDs
Enriched GO Terms of Interacting Partners?		Spinal Cord Oligodendrocyte Cell Differentiation Oligodendrocyte Cell Fate Specification Glial Cell Fate Specification Spinal Cord Oligodendrocyte Cell Fate Specification Engulfment Of Apoptotic Cell Recognition Of Apoptotic Cell Skeletal Muscle Satellite Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Complement Component C1q Complex Binding Myoblast Development Skeletal Muscle Satellite Cell Activation HMG Box Domain Binding Thalamus Development Skeletal Muscle Cell Proliferation Phagocytosis, Recognition Myoblast Migration Positive Regulation Of Myoblast Proliferation Spinal Cord Motor Neuron Differentiation Positive Regulation Of Oligodendrocyte Differentiation Regulation Of Skeletal Muscle Tissue Development Regulation Of Myoblast Proliferation Scavenger Receptor Activity Notch Binding Apoptotic Cell Clearance Phagocytic Cup Muscle Cell Migration Phagocytosis, Engulfment Cell Differentiation In Spinal Cord Neuron Fate Commitment Positive Regulation Of Glial Cell Differentiation Regulation Of Oligodendrocyte Differentiation Apoptotic Process Involved In Development Oligodendrocyte Differentiation Muscle Cell Proliferation Regulation Of Striated Muscle Tissue Development Regulation Of Muscle Organ Development Membrane Invagination Axon Development E-box Binding Animal Organ Development Skeletal Muscle Cell Differentiation Positive Regulation Of Gliogenesis Homotypic Cell-cell Adhesion Regulation Of Glial Cell Differentiation Regulation Of Cell Differentiation Negative Regulation Of Neuron Differentiation Cell Fate Specification Myelination Axon Ensheathment Muscle Cell Development	Oligodendrocyte Differentiation Regulation Of Neuron Differentiation Positive Regulation Of Gliogenesis Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Neuron Differentiation Enteric Nervous System Development Regulation Of Gliogenesis Glial Cell Differentiation Negative Regulation Of Transcription By RNA Polymerase II Chromatin Oligodendrocyte Development Regulation Of Neurogenesis Peripheral Nervous System Development Regulation Of Cell Development Negative Regulation Of RNA Biosynthetic Process Peptidyl-lysine Propionylation Swimming Cell Fate Commitment Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Negative Regulation Of DNA-templated Transcription Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Positive Regulation Of Cell Differentiation Positive Regulation Of Cell Development Histone Crotonyltransferase Activity DNA-binding Transcription Factor Binding Regulation Of Cell Division Response To Progesterone Ventral Spinal Cord Interneuron Fate Determination Type B Pancreatic Cell Fate Commitment Regulation Of Nervous System Development Transcription Elongation By RNA Polymerase II Positive Regulation Of Cytokinesis Microtubule Plus End Polymerase Histone H2B Acetyltransferase Activity Animal Organ Development Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Protein Destabilization Histone H3K27 Acetyltransferase Activity Peptide Crotonyltransferase Activity Positive Regulation Of TORC1 Signaling Histone Acetyltransferase Regulator Activity Pancreatic A Cell Fate Commitment
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