MAST3 and MYCBP2

		MAST3	MYCBP2
Description		microtubule associated serine/threonine kinase 3	MYC binding protein 2
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GO Annotations	Cellular Component	Cytoplasm Microtubule Cytoskeleton	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Membrane Axon Cell Projection
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Transferase Activity Small GTPase Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cytoskeleton Organization Intracellular Signal Transduction	Axon Guidance Motor Neuron Axon Guidance Regulation Of Synaptic Assembly At Neuromuscular Junction Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Rhythmic Process Cell Morphogenesis Involved In Neuron Differentiation Neuromuscular Process Regulation Of Cytoskeleton Organization Axon Development Protein K48-linked Ubiquitination Regulation Of Axon Guidance
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Adult body size ( 32376654) Alanine aminotransferase levels ( 33547301) Body fat mass ( 28552196) Eosinophil percentage of white cells ( 32888494) Glycine levels ( 30837465) Liver enzyme levels (alanine transaminase) ( 33972514) Mental health study participation (completed survey) ( 31263887) Number of sexual partners ( 30643258) Percent liver fat ( 34128465) Red cell distribution width ( 32888494) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Walking pace ( 33128006)	Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		2 interacting genes: CNTNAP4 PTEN	50 interacting genes: AATF APPL1 ARL6IP5 ASB8 ATP13A2 BTG3 CALM1 CD81 CEBPA CFL1 CUEDC2 DHRS4L2 DSCR9 DYRK1A ERBB3 FHL3 FSCN1 HSP90AB1 HUNK IGFBP6 LCOR LDHB LSM14A MYC NDUFB9 NMNAT2 OAZ1 PABPN1 PI4KB PRXL2A PTPN12 PUF60 RGPD8 RPS5 RSPH1 SERPINB6 SOD1 SPARCL1 SPRYD3 SRPK2 TBC1D9 TBC1D9B TBR1 TTN UBE2D2 UBE2D3 UBE2L3 UCHL1 YWHAG YWHAQ
Entrez ID		23031	23077
HPRD ID		19403	10104
Ensembl ID		ENSG00000099308	ENSG00000005810
Uniprot IDs		A0A8I5KST9 A0A8V8TLL8 A0A8V8TMW0 O60307	O75592
PDB IDs		1V9V 3KHF	5O6C 6T7F
Enriched GO Terms of Interacting Partners?		Central Nervous System Neuron Axonogenesis Regulation Of Growth Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Developmental Growth Regulation Of Developmental Growth Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Lung Development Response To Metformin Putamen Development Caudate Nucleus Development Central Nervous System Myelin Maintenance Circadian Rhythm Rhythmic Synaptic Transmission Regulation Of Grooming Behavior Locomotor Rhythm Regulation Of Cell Junction Assembly Cell Projection Morphogenesis Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Cellular Response To Electrical Stimulus Learning Or Memory Negative Regulation Of Growth Regulation Of Locomotion Ubiquitin Ligase Activator Activity Spindle Assembly Involved In Female Meiosis Neuron Projection Morphogenesis Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Synaptic Vesicle Clustering Postsynaptic Specialization Assembly Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Neuron-neuron Synaptic Transmission Phosphatidylinositol Phosphate Phosphatase Activity Negative Regulation Of Cell Size Presynaptic Membrane Organization Schmidt-Lanterman Incisure Anaphase-promoting Complex Binding Postsynaptic Density Assembly Rhythmic Process Forebrain Morphogenesis Negative Regulation Of Excitatory Postsynaptic Potential Axonogenesis Presynaptic Membrane Assembly Nervous System Process GDF15-GFRAL Signaling Pathway Regulation Of Growth Hormone Receptor Signaling Pathway Negative Regulation Of Appetite Negative Regulation Of Growth Hormone Receptor Signaling Pathway	Cytoplasm Intracellular Signal Transduction
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