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EXOSC7 and SKIV2L2
Number of citations of the paper that reports this interaction (PMID
11719186
)
268
Data Source:
HPRD
(in vivo)
EXOSC7
SKIV2L2
Gene Name
exosome component 7
superkiller viralicidic activity 2-like 2 (S. cerevisiae)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Exosome (RNase Complex)
Nucleus
Nucleolus
Cytosol
Exosome (RNase Complex)
Nucleus
Nucleoplasm
Nucleolus
Catalytic Step 2 Spliceosome
Molecular Function
3'-5'-exoribonuclease Activity
RNA Binding
Exoribonuclease Activity
Protein Binding
Helicase Activity
Protein Binding
ATP Binding
Poly(A) RNA Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
RRNA Processing
RNA Catabolic Process
Gene Expression
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
MRNA Splicing, Via Spliceosome
Maturation Of 5.8S RRNA
Pathways
Regulation of mRNA stability by proteins that bind AU-rich elements
KSRP destabilizes mRNA
mRNA decay by 3' to 5' exoribonuclease
ATF4 activates genes
Tristetraprolin (TTP) destabilizes mRNA
PERK regulates gene expression
Unfolded Protein Response (UPR)
Deadenylation-dependent mRNA decay
Butyrate Response Factor 1 (BRF1) destabilizes mRNA
Drugs
Diseases
GWAS
Protein-Protein Interactions
14 interactors:
APP
DIS3
DXO
EXOSC1
EXOSC10
EXOSC2
EXOSC4
EXOSC5
EXOSC6
EXOSC8
EXOSC9
IP6K1
MPP6
SKIV2L2
14 interactors:
DIS3
EXOSC2
EXOSC4
EXOSC5
EXOSC6
EXOSC7
EXOSC8
EXOSC9
MPHOSPH6
MPP6
PBX2
SP1
UPF2
XRN1
Entrez ID
23016
23517
HPRD ID
09401
13777
Ensembl ID
ENSG00000075914
ENSG00000039123
Uniprot IDs
B2RDZ9
Q15024
P42285
Q3MHC9
PDB IDs
2NN6
Enriched GO Terms of Interacting Partners
?
RRNA Processing
RRNA Metabolic Process
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Ribosome Biogenesis
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Nuclear-transcribed MRNA Catabolic Process
MRNA Catabolic Process
RNA Catabolic Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Ribonucleoprotein Complex Biogenesis
MRNA Metabolic Process
NcRNA Metabolic Process
Nuclear MRNA Surveillance
RNA Surveillance
Aromatic Compound Catabolic Process
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Maturation Of 5.8S RRNA
Cellular Macromolecule Catabolic Process
RNA Phosphodiester Bond Hydrolysis
RRNA Catabolic Process
RNA Metabolic Process
Nucleic Acid Phosphodiester Bond Hydrolysis
Nuclear Polyadenylation-dependent RRNA Catabolic Process
CUT Catabolic Process
Catabolic Process
Nucleobase-containing Compound Metabolic Process
DNA Deamination
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Gene Expression
Cellular Metabolic Process
Histone MRNA Catabolic Process
Intracellular MRNA Localization
DNA Modification
Positive Regulation Of Cell Growth
Histone MRNA Metabolic Process
RNA Processing
Positive Regulation Of Growth
Regulation Of Growth
Metabolic Process
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Regulation Of Cell Growth
Nuclear Polyadenylation-dependent TRNA Catabolic Process
Synaptic Growth At Neuromuscular Junction
Polyadenylation-dependent SnoRNA 3'-end Processing
Nuclear Retention Of Pre-mRNA With Aberrant 3'-ends At The Site Of Transcription
U4 SnRNA 3'-end Processing
RNA 3'-end Processing
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
RRNA Metabolic Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
RRNA Processing
Nuclear-transcribed MRNA Catabolic Process
MRNA Catabolic Process
RNA Catabolic Process
Ribosome Biogenesis
NcRNA Metabolic Process
Ribonucleoprotein Complex Biogenesis
Aromatic Compound Catabolic Process
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
MRNA Metabolic Process
RNA Metabolic Process
Nuclear MRNA Surveillance
Cellular Macromolecule Catabolic Process
RNA Surveillance
RNA Phosphodiester Bond Hydrolysis
RRNA Catabolic Process
Nucleobase-containing Compound Metabolic Process
Nucleic Acid Phosphodiester Bond Hydrolysis
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Maturation Of 5.8S RRNA
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Catabolic Process
Gene Expression
DNA Deamination
Nuclear Polyadenylation-dependent RRNA Catabolic Process
CUT Catabolic Process
Cellular Metabolic Process
Histone MRNA Catabolic Process
DNA Modification
Positive Regulation Of Cell Growth
Histone MRNA Metabolic Process
Positive Regulation Of Growth
Metabolic Process
Sequestering Of Nodal From Receptor Via Nodal Binding
Regulation Of Cell Growth
Negative Regulation Of Nodal Signaling Pathway
Nuclear Polyadenylation-dependent TRNA Catabolic Process
Polyadenylation-dependent SnoRNA 3'-end Processing
Nuclear Retention Of Pre-mRNA With Aberrant 3'-ends At The Site Of Transcription
U4 SnRNA 3'-end Processing
TRNA Catabolic Process
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5'
Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
SnoRNA Metabolic Process
Tagcloud
?
accessed
actg1
affymetrix
b2m
bafl
bioinformatics
broadly
c12orf35
cbaciu
de
devastating
dynlt1
edu
filtering
handle
html
ilkap
lo
pipeline
qrt
reasonable
sals
suite
supplementary
tardbp
tm4
twelve
uncc
webpages
Tagcloud (Difference)
?
accessed
actg1
affymetrix
b2m
bafl
bioinformatics
broadly
c12orf35
cbaciu
de
devastating
dynlt1
edu
filtering
handle
html
ilkap
lo
pipeline
qrt
reasonable
sals
suite
supplementary
tardbp
tm4
twelve
uncc
webpages
Tagcloud (Intersection)
?