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P2RX2 and GABRR1
Number of citations of the paper that reports this interaction (PMID
14660627
)
11
Data Source:
HPRD
(in vitro, in vivo)
P2RX2
GABRR1
Gene Name
purinergic receptor P2X, ligand gated ion channel, 2
gamma-aminobutyric acid (GABA) A receptor, rho 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Integral Component Of Nuclear Inner Membrane
Integral Component Of Plasma Membrane
Cell Surface
Postsynaptic Density
Apical Plasma Membrane
Presynaptic Membrane
Neuronal Cell Body
Terminal Bouton
Dendritic Spine
Receptor Complex
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Junction
Chloride Channel Complex
Postsynaptic Membrane
Molecular Function
Purinergic Nucleotide Receptor Activity
Extracellular ATP-gated Cation Channel Activity
Copper Ion Binding
ATP Binding
Drug Binding
Zinc Ion Binding
Ligand-gated Ion Channel Activity
Nickel Cation Binding
Phosphatidylinositol Binding
Identical Protein Binding
Mercury Ion Binding
Cadmium Ion Binding
Cobalt Ion Binding
GABA-A Receptor Activity
Extracellular Ligand-gated Ion Channel Activity
Chloride Channel Activity
Biological Process
Response To Hypoxia
Detection Of Hypoxic Conditions In Blood By Carotid Body Chemoreceptor Signaling
Neuromuscular Synaptic Transmission
Neuromuscular Junction Development
Sensory Perception Of Sound
Response To Carbohydrate
Positive Regulation Of Calcium Ion Transport Into Cytosol
Urinary Bladder Smooth Muscle Contraction
Neuronal Action Potential
Peristalsis
Response To ATP
Purinergic Nucleotide Receptor Signaling Pathway
Behavioral Response To Pain
Skeletal Muscle Fiber Development
Positive Regulation Of Calcium-mediated Signaling
Sensory Perception Of Taste
Protein Homooligomerization
Protein Heterooligomerization
Cation Transmembrane Transport
Transport
Gamma-aminobutyric Acid Signaling Pathway
Synaptic Transmission
Ion Transmembrane Transport
Transmembrane Transport
Chloride Transmembrane Transport
Pathways
GABA receptor activation
GABA A (rho) receptor activation
Ion channel transport
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Ligand-gated ion channel transport
Transmission across Chemical Synapses
Drugs
Lorazepam
Temazepam
Clobazam
Alprazolam
Picrotoxin
Chlordiazepoxide
Adinazolam
Clorazepate
Midazolam
Flurazepam
Halazepam
Diazepam
Oxazepam
Triazolam
Clonazepam
Estazolam
Bromazepam
Clotiazepam
Fludiazepam
Prazepam
Quazepam
Cinolazepam
Nitrazepam
Diseases
GWAS
Bipolar disorder and schizophrenia (
20889312
)
Protein-Protein Interactions
3 interactors:
GABRR1
P2RX1
P2RX3
10 interactors:
CSNK2A1
GABRR2
MAP1B
MAPK1
P2RX2
PRKACA
PRKCA
PRKG1
SLC6A9
SQSTM1
Entrez ID
22953
2569
HPRD ID
15984
15921
Ensembl ID
ENSG00000187848
ENSG00000146276
Uniprot IDs
Q32MC3
Q9UBL9
P24046
PDB IDs
Enriched GO Terms of Interacting Partners
?
Response To ATP
Neuronal Action Potential
Purinergic Nucleotide Receptor Signaling Pathway
Synaptic Transmission
Transmission Of Nerve Impulse
Action Potential
Cell-cell Signaling
Response To Organophosphorus
Response To Purine-containing Compound
Ion Transmembrane Transport
Regulation Of Calcium Ion Transport
Positive Regulation Of Ion Transport
Protein Homooligomerization
Serotonin Secretion By Platelet
Inorganic Anion Transport
Regulation Of Membrane Potential
Transmembrane Transport
Ion Transport
Serotonin Secretion
Regulation Of Vascular Smooth Muscle Contraction
Serotonin Transport
Protein Oligomerization
Urinary Bladder Smooth Muscle Contraction
Peristalsis
Regulation Of Ion Transport
Insemination
Anion Transport
Cell Surface Receptor Signaling Pathway
Behavioral Response To Pain
Copulation
Positive Regulation Of Transport
Neuromuscular Synaptic Transmission
Monoamine Transport
Positive Regulation Of Calcium-mediated Signaling
Production Of Molecular Mediator Involved In Inflammatory Response
Response To Organonitrogen Compound
Gamma-aminobutyric Acid Signaling Pathway
Response To Organic Cyclic Compound
Vasoconstriction
Cation Transmembrane Transport
Positive Regulation Of Calcium Ion Transport Into Cytosol
Response To Pain
Synaptic Transmission, Glutamatergic
Regulation Of Calcium-mediated Signaling
Protein Complex Assembly
Ceramide Biosynthetic Process
Mating
Regulation Of Smooth Muscle Contraction
Neurological System Process
Response To Cold
Regulation Of Platelet Aggregation
Positive Regulation Of Dense Core Granule Biogenesis
Regulation Of Platelet Activation
Histone H3-T6 Phosphorylation
Peptidyl-threonine Phosphorylation
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Synaptic Transmission
Peptidyl-serine Autophosphorylation
Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Protein Phosphorylation
Cell Differentiation
Desmosome Assembly
Negative Regulation Of Glial Cell Apoptotic Process
Regulation Of Blood Coagulation
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Negative Regulation Of Glucose Import
Movement Of Cell Or Subcellular Component
Positive Regulation Of Macrophage Differentiation
Desmosome Organization
Peptidyl-serine Phosphorylation
Cell-cell Signaling
Blood Coagulation
Regulation Of Wound Healing
Hemostasis
Regulation Of Intracellular Transport
Negative Regulation Of Glucose Transport
Apoptotic Process
Induction Of Positive Chemotaxis
Positive Regulation Of Cardiac Muscle Hypertrophy
Programmed Cell Death
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Cell Development
Regulation Of Cellular Localization
Regulation Of Muscle Contraction
Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Cell Death
Death
Phosphorylation
Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Adenylate Cyclase Activity
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Negative Regulation Of Lyase Activity
Regulation Of Rhodopsin Mediated Signaling Pathway
Response To Carbohydrate
Cellular Response To Fibroblast Growth Factor Stimulus
Cell Surface Receptor Signaling Pathway
Response To Fibroblast Growth Factor
Platelet Activation
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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