P2RX2

Description		purinergic receptor P2X 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Apical Plasma Membrane Neuronal Cell Body Receptor Complex Synapse Postsynapse Neuronal Dense Core Vesicle
	Molecular Function	Nucleotide Binding Purinergic Nucleotide Receptor Activity Extracellularly ATP-gated Monoatomic Cation Channel Activity Monoatomic Ion Channel Activity ATP Binding Ligand-gated Monoatomic Ion Channel Activity Identical Protein Binding
	Biological Process	Response To Hypoxia Response To Ischemia Detection Of Hypoxic Conditions In Blood By Carotid Body Chemoreceptor Signaling Monoatomic Ion Transport Chemical Synaptic Transmission Neuromuscular Synaptic Transmission Neuromuscular Junction Development Sensory Perception Of Sound Response To Carbohydrate Positive Regulation Of Calcium Ion Transport Into Cytosol Urinary Bladder Smooth Muscle Contraction Peristalsis Response To ATP Monoatomic Ion Transmembrane Transport Purinergic Nucleotide Receptor Signaling Pathway Behavioral Response To Pain Skeletal Muscle Fiber Development Positive Regulation Of Calcium-mediated Signaling Sensory Perception Of Taste Excitatory Postsynaptic Potential Calcium Ion Transmembrane Transport Monoatomic Cation Transmembrane Transport
Pathways		Elevation of cytosolic Ca2+ levels Platelet homeostasis
Drugs		Promethazine
Diseases
GWAS		Body mass index ( 26426971)
Interacting Genes		4 interacting genes: GABRA1 GABRR1 P2RX1 P2RX3
Entrez ID		22953
HPRD ID		15984
Ensembl ID		ENSG00000187848
Uniprot IDs		Q32MC3 Q9UBL9
PDB IDs
Enriched GO Terms of Interacting Partners?		Monoatomic Ion Channel Activity Trans-synaptic Signaling Synaptic Signaling Chemical Synaptic Transmission Regulation Of Membrane Potential GABA Receptor Activity Regulation Of Postsynaptic Membrane Potential Purinergic Nucleotide Receptor Activity Extracellularly ATP-gated Monoatomic Cation Channel Activity Cell-cell Signaling Signaling Cell Communication Inorganic Ion Transmembrane Transport Monoatomic Ion Transmembrane Transport GABA-gated Chloride Ion Channel Activity GABA-A Receptor Activity GABA-A Receptor Complex Monoatomic Ion Transport Postsynaptic Membrane Purinergic Nucleotide Receptor Signaling Pathway Gamma-aminobutyric Acid Signaling Pathway Transmembrane Transport Response To ATP Synaptic Transmission, GABAergic Extracellular Ligand-gated Monoatomic Ion Channel Activity Chloride Channel Complex Positive Regulation Of Calcium Ion Transmembrane Transport Excitatory Postsynaptic Potential Chloride Channel Activity Modulation Of Chemical Synaptic Transmission Chloride Transmembrane Transport Positive Regulation Of Calcium Ion Transport GABA-ergic Synapse Chloride Transport Inorganic Anion Transmembrane Transport Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Monoatomic Ion Transmembrane Transport Monoatomic Anion Transmembrane Transport Inorganic Anion Transport Monoatomic Anion Transport Response To Purine-containing Compound Regulation Of Calcium Ion Transmembrane Transport Suramin Binding Regulation Of Biological Quality GABA Receptor Complex Serotonin Secretion By Platelet Positive Regulation Of Monoatomic Ion Transport Calcium Ion Transmembrane Transport Serotonin Secretion Insemination
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