GABRR1

Gene Name		gamma-aminobutyric acid (GABA) A receptor, rho 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Chloride Channel Complex Postsynaptic Membrane
	Molecular Function	GABA-A Receptor Activity Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity
	Biological Process	Transport Gamma-aminobutyric Acid Signaling Pathway Synaptic Transmission Ion Transmembrane Transport Transmembrane Transport Chloride Transmembrane Transport
Pathways		GABA receptor activation GABA A (rho) receptor activation Ion channel transport Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ligand-gated ion channel transport Transmission across Chemical Synapses
Drugs		Lorazepam Temazepam Clobazam Alprazolam Picrotoxin Chlordiazepoxide Adinazolam Clorazepate Midazolam Flurazepam Halazepam Diazepam Oxazepam Triazolam Clonazepam Estazolam Bromazepam Clotiazepam Fludiazepam Prazepam Quazepam Cinolazepam Nitrazepam
Diseases
GWAS		Bipolar disorder and schizophrenia ( 20889312)
Protein-protein Interactions		10 interactors: CSNK2A1 GABRR2 MAP1B MAPK1 P2RX2 PRKACA PRKCA PRKG1 SLC6A9 SQSTM1
Entrez ID		2569
HPRD ID		15921
Ensembl ID		ENSG00000146276
Uniprot IDs		P24046
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Platelet Aggregation Positive Regulation Of Dense Core Granule Biogenesis Regulation Of Platelet Activation Histone H3-T6 Phosphorylation Peptidyl-threonine Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Synaptic Transmission Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Protein Phosphorylation Cell Differentiation Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Blood Coagulation Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Glucose Import Movement Of Cell Or Subcellular Component Positive Regulation Of Macrophage Differentiation Desmosome Organization Peptidyl-serine Phosphorylation Cell-cell Signaling Blood Coagulation Regulation Of Wound Healing Hemostasis Regulation Of Intracellular Transport Negative Regulation Of Glucose Transport Apoptotic Process Induction Of Positive Chemotaxis Positive Regulation Of Cardiac Muscle Hypertrophy Programmed Cell Death Positive Regulation Of Blood Vessel Endothelial Cell Migration Cell Development Regulation Of Cellular Localization Regulation Of Muscle Contraction Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cell Death Death Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Negative Regulation Of Lyase Activity Regulation Of Rhodopsin Mediated Signaling Pathway Response To Carbohydrate Cellular Response To Fibroblast Growth Factor Stimulus Cell Surface Receptor Signaling Pathway Response To Fibroblast Growth Factor Platelet Activation
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