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SSSCA1 and CCNH
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
HPRD
(two hybrid)
SSSCA1
CCNH
Gene Name
Sjogren syndrome/scleroderma autoantigen 1
cyclin H
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Holo TFIIH Complex
Cyclin-dependent Protein Kinase Activating Kinase Holoenzyme Complex
TFIIK Complex
Molecular Function
Protein Binding
Identical Protein Binding
Protein Binding
DNA-dependent ATPase Activity
RNA Polymerase II Carboxy-terminal Domain Kinase Activity
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Protein Kinase Binding
Biological Process
Mitotic Nuclear Division
Cell Division
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
G1/S Transition Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Nucleotide-excision Repair, DNA Damage Removal
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Protein Phosphorylation
Gene Expression
Viral Process
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Viral Transcription
Pathways
RNA Polymerase II Promoter Escape
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Tat-mediated elongation of the HIV-1 transcript
Cyclin E associated events during G1/S transition
Formation of transcription-coupled NER (TC-NER) repair complex
Dual incision reaction in TC-NER
NoRC negatively regulates rRNA expression
G1/S Transition
Mitotic G1-G1/S phases
S Phase
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
Global Genomic NER (GG-NER)
RNA Polymerase II Transcription Initiation And Promoter Clearance
Cyclin A:Cdk2-associated events at S phase entry
Mitotic G2-G2/M phases
Transcription of the HIV genome
Nucleotide Excision Repair
RNA Polymerase II Transcription
RNA Polymerase I Transcription Initiation
HIV Infection
RNA Polymerase I Promoter Clearance
Formation of the Early Elongation Complex
G2/M Transition
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
HIV Transcription Initiation
HIV Life Cycle
RNA Pol II CTD phosphorylation and interaction with CE
Cyclin A/B1 associated events during G2/M transition
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
Dual incision reaction in GG-NER
RNA Polymerase I Transcription
mRNA Capping
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Termination
G1 Phase
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
Cell Cycle, Mitotic
Cyclin D associated events in G1
Transcription-coupled NER (TC-NER)
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
Formation of incision complex in GG-NER
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Height (
20881960
)
Major depressive disorder (
23377640
)
Protein-Protein Interactions
20 interactors:
ALS2CR11
C20orf195
CCDC33
CCNH
CCT2
CCT3
CCT5
CCT7
FXR2
IL16
MYO15B
NME6
NOC4L
RNF115
SNAPC5
STAT3
SUMO1P1
TRAF3IP3
TRAPPC6A
VTA1
39 interactors:
AR
CALCOCO2
CCDC170
CCDC33
CCNC
CDK2
CDK20
CDK7
CDK8
CSNK2B
CTBP2
CTD
DUSP12
ERCC3
ESR1
FUBP1
GANAB
GOLGA2
GTF2E2
GTF2H1
KLC3
MBP
MCM7
MNAT1
MTA1
MYC
NDC80
NEDD4
POLR2A
POLR2B
PPFIA1
PSMA1
RARB
SFN
SSSCA1
SSX2IP
SUPT5H
TP53
TRIM8
Entrez ID
10534
902
HPRD ID
06921
09059
Ensembl ID
ENSG00000173465
ENSG00000134480
Uniprot IDs
O60232
P51946
PDB IDs
1JKW
1KXU
Enriched GO Terms of Interacting Partners
?
Toxin Transport
Binding Of Sperm To Zona Pellucida
Sperm-egg Recognition
'de Novo' Posttranslational Protein Folding
'de Novo' Protein Folding
Cell-cell Recognition
Cell Recognition
Single Fertilization
Fertilization
Protein Folding
Sexual Reproduction
Viral Process
Reproduction
Reproductive Process
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Transcription From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine RNA Capping
Regulation Of Viral Transcription
DNA-templated Transcription, Elongation
Positive Regulation Of Viral Transcription
Viral Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Viral Process
Positive Regulation Of Cellular Biosynthetic Process
Transcription-coupled Nucleotide-excision Repair
Regulation Of Viral Process
Nucleotide-excision Repair
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Metabolic Process
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Transcription, DNA-templated
Transcription, DNA-templated
RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Cell Cycle
Cellular Response To Stress
Nucleotide-excision Repair, DNA Damage Removal
Regulation Of Transcription From RNA Polymerase II Promoter
RNA Metabolic Process
Cell Cycle
Gene Expression
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Regulation Of RNA Biosynthetic Process
Mitotic Cell Cycle
Transcription Initiation From RNA Polymerase I Promoter
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Transcription From RNA Polymerase I Promoter
DNA Repair
Cellular Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
DNA Metabolic Process
Negative Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Heterocycle Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Tagcloud
?
carrying
chemotherapy
conversely
ercc5
ercc6
genotype
genotypes
genotyping
good
homozygous
hrs
longer
median
mms19l
months
os
osteosarcoma
pfs
polymorphisms
poor
rflp
rs1047768
rs17655
rs29001322
shorter
tt
undergoing
xpc
Tagcloud (Difference)
?
carrying
chemotherapy
conversely
ercc5
ercc6
genotype
genotypes
genotyping
good
homozygous
hrs
longer
median
mms19l
months
os
osteosarcoma
pfs
polymorphisms
poor
rflp
rs1047768
rs17655
rs29001322
shorter
tt
undergoing
xpc
Tagcloud (Intersection)
?