ZNRD2 and NME6

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		ZNRD2	NME6
Description		zinc ribbon domain containing 2	NME/NM23 nucleoside diphosphate kinase 6
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Protein Binding Identical Protein Binding Metal Ion Binding	Nucleotide Binding Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Metal Ion Binding
	Biological Process	Mitotic Cell Cycle Cell Division	GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Apoptotic Process Nucleotide Metabolic Process Pyrimidine Ribonucleotide Salvage Negative Regulation Of Cell Growth Negative Regulation Of Mitotic Nuclear Division
Pathways
Drugs
Diseases
GWAS		Glaucoma (primary open-angle) ( 33627673)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		27 interacting genes: ACTN2 CATSPERT CCDC33 CCNH CCT2 CCT3 CCT5 CCT7 FNDC11 FXR2 IL16 INCA1 MYO15B NME6 NOC4L PIAS2 RNF115 RNF4 SNAPC5 STAT3 SUMO1P1 TRAF3IP3 TRAPPC6A UBC UBE2I VTA1 ZMYM5	3 interacting genes: APP ATP5PO ZNRD2
Entrez ID		10534	10201
HPRD ID		06921	09219
Ensembl ID		ENSG00000173465	ENSG00000172113
Uniprot IDs		G3V1B8 O60232	A0A0C4DG91 A0A2R8Y7V2 C9JQB1 O75414
PDB IDs		6HCZ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Protein Localization To Cajal Body Chaperonin-containing T-complex Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Binding Of Sperm To Zona Pellucida ATP-dependent Protein Folding Chaperone Sperm-egg Recognition Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Biosynthetic Process Regulation Of Telomere Maintenance Via Telomere Lengthening Cell-cell Recognition Protein Folding Chaperone Positive Regulation Of Telomere Maintenance Cell Body Regulation Of DNA Biosynthetic Process Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Chromosome Organization PML Body Regulation Of Telomere Maintenance Unfolded Protein Binding Protein Stabilization Regulation Of Chromosome Organization Cell Recognition Zona Pellucida Receptor Complex Protein Sumoylation Regulation Of Protein Localization To Nucleus Protein Tag Activity Regulation Of Protein Stability Protein Folding Transcription Factor Binding SUMO Transferase Activity Protein Modification By Small Protein Conjugation Positive Regulation Of DNA Metabolic Process Positive Regulation Of Organelle Organization Actin Filament Uncapping SUMO Conjugating Enzyme Activity RNA Polymerase II General Transcription Initiation Factor Activity Protein K11-linked Ubiquitination Post-translational Protein Modification Microtubule	Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Response To CAMP Acetylcholine Receptor Activator Activity PTB Domain Binding Response To Purine-containing Compound Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Estradiol Binding Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel
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