ZNRD2 and SNAPC5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ZNRD2	SNAPC5
Description		zinc ribbon domain containing 2	small nuclear RNA activating complex polypeptide 5
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GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Nucleolus Nuclear Body
	Molecular Function	Protein Binding Identical Protein Binding Metal Ion Binding	RNA Polymerase III General Transcription Initiation Factor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity
	Biological Process	Mitotic Cell Cycle Cell Division	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase III Promoter SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III
Pathways			RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Glaucoma (primary open-angle) ( 33627673)
Interacting Genes		27 interacting genes: ACTN2 CATSPERT CCDC33 CCNH CCT2 CCT3 CCT5 CCT7 FNDC11 FXR2 IL16 INCA1 MYO15B NME6 NOC4L PIAS2 RNF115 RNF4 SNAPC5 STAT3 SUMO1P1 TRAF3IP3 TRAPPC6A UBC UBE2I VTA1 ZMYM5	43 interacting genes: AMOT ARHGEF38 BATF BFSP2 BLOC1S1 BRCC3 CBY2 CCDC196 CDCA8 CREB5 CREBBP CYTH1 CYTH4 DDIT3 EMILIN1 FAM9C GALR1 GORAB GRIPAP1 HMG20B ITGB3BP JUN LMO2 MBD3L1 MCRS1 MYF5 NDEL1 NMI NOL4 NUDT10 NUP62 POLR2J RNF4 S100Z SNAPC1 SNAPC4 STMN4 TRAPPC2 TRAPPC2B TXLNB ZNF177 ZNF559-ZNF177 ZNRD2
Entrez ID		10534	10302
HPRD ID		06921	16183
Ensembl ID		ENSG00000173465	ENSG00000174446
Uniprot IDs		G3V1B8 O60232	O75971
PDB IDs		6HCZ	7ZWC 7ZWD 7ZX7 7ZX8 7ZXE
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Protein Localization To Cajal Body Chaperonin-containing T-complex Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Binding Of Sperm To Zona Pellucida ATP-dependent Protein Folding Chaperone Sperm-egg Recognition Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Biosynthetic Process Regulation Of Telomere Maintenance Via Telomere Lengthening Cell-cell Recognition Protein Folding Chaperone Positive Regulation Of Telomere Maintenance Cell Body Regulation Of DNA Biosynthetic Process Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Chromosome Organization PML Body Regulation Of Telomere Maintenance Unfolded Protein Binding Protein Stabilization Regulation Of Chromosome Organization Cell Recognition Zona Pellucida Receptor Complex Protein Sumoylation Regulation Of Protein Localization To Nucleus Protein Tag Activity Regulation Of Protein Stability Protein Folding Transcription Factor Binding SUMO Transferase Activity Protein Modification By Small Protein Conjugation Positive Regulation Of DNA Metabolic Process Positive Regulation Of Organelle Organization Actin Filament Uncapping SUMO Conjugating Enzyme Activity RNA Polymerase II General Transcription Initiation Factor Activity Protein K11-linked Ubiquitination Post-translational Protein Modification Microtubule	SnRNA-activating Protein Complex Peptidyl-lysine Acetylation Protein Binding Integrated Stress Response Signaling RNA Polymerase II Transcription Regulator Complex CAMP Response Element Binding TRAPPII Protein Complex TRAPPIII Protein Complex SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III RNA Polymerase III General Transcription Initiation Factor Activity Positive Regulation Of Mitotic Cytokinesis Centrosome Separation Mitotic Centrosome Separation SnRNA Transcription Regulation Of Mitotic Cytokinesis
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