SHANK2 and BAIAP2

Number of citations of the paper that reports this interaction (PMID 12504591)
14

Data Source:
HPRD (in vitro)

		SHANK2	BAIAP2
Gene Name		SH3 and multiple ankyrin repeat domains 2	BAI1-associated protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cellular_component Neurofilament Plasma Membrane Ionotropic Glutamate Receptor Complex Postsynaptic Density Apical Plasma Membrane Cell Junction Growth Cone Brush Border Membrane Neuron Projection Neuronal Cell Body Dendritic Spine Postsynaptic Membrane Ciliary Membrane	Ruffle Nucleoplasm Cytoplasm Cytosol Plasma Membrane Actin Cytoskeleton Filopodium Neuron Projection Extracellular Vesicular Exosome
	Molecular Function	Protein Binding SH3 Domain Binding GKAP/Homer Scaffold Activity Ionotropic Glutamate Receptor Binding	Protein Binding Protein C-terminus Binding Cytoskeletal Adaptor Activity Identical Protein Binding Proline-rich Region Binding
	Biological Process	Synapse Assembly Learning Memory Adult Behavior Social Behavior Exploration Behavior Long-term Synaptic Potentiation Long Term Synaptic Depression Vocalization Behavior	Plasma Membrane Organization Axonogenesis Insulin Receptor Signaling Pathway Regulation Of Cell Shape Response To Bacterium Dendrite Development Regulation Of Actin Cytoskeleton Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Synaptic Plasticity Actin Filament Bundle Assembly Actin Crosslink Formation
Pathways			Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Response to fenofibrate (adiponectin levels) ( 23149075)
Protein-Protein Interactions		15 interactors: ARHGEF7 BAI2 BAIAP2 CTTN DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 DNM2 LPHN1 LPHN2 SHARPIN SLC9A3 SSTR2	32 interactors: APP ATN1 BAI1 C14orf1 C19orf25 CDC42 DIAPH1 ENAH EPS8 ESPN KANK1 KDM1A LIN7A LIN7B LIN7C MARK2 NCKIPSD NEDD4 PAK1 PBX2 PRR13 RAC1 RTN4 SF3B4 SHANK1 SHANK2 SRPK2 TP53BP2 WASF1 WASF2 WASL YWHAG
Entrez ID		22941	10458
HPRD ID		04479	05686
Ensembl ID		ENSG00000162105	ENSG00000175866
Uniprot IDs		C0SPH0 Q9UPX8	B4DWA1 I3L4C2 Q9UQB8
PDB IDs			1WDZ 1Y2O 2YKT 3RNJ
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Signaling Cell Communication Synaptic Transmission Nervous System Development Neuron Projection Morphogenesis Dendritic Spine Organization Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Cell Morphogenesis Focal Adhesion Assembly Neuron Development Cell Morphogenesis Adherens Junction Assembly Lamellipodium Organization Neuron Differentiation Cell-substrate Junction Assembly Cell Projection Organization Endocytosis Regulation Of Cellular Component Organization Regulation Of Axon Extension Negative Regulation Of Membrane Tubulation Post-Golgi Vesicle-mediated Transport Adherens Junction Organization System Development Regulation Of CD40 Signaling Pathway Protein Linear Polyubiquitination Positive Regulation Of Lamellipodium Morphogenesis Generation Of Neurons Synaptic Vesicle Transport Neurogenesis Somatostatin Signaling Pathway Regulation Of Cell Size Regulation Of Cell Projection Organization Dendrite Development Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Cell Development Multicellular Organismal Development Axonogenesis Maintenance Of Apical/basal Cell Polarity Regulation Of Lamellipodium Morphogenesis Regulation Of Axonogenesis Regulation Of Synaptic Plasticity Cellular Component Assembly G-protein Coupled Receptor Signaling Pathway Anatomical Structure Development Receptor Localization To Synapse Dendritic Spine Maintenance	Regulation Of Cytoskeleton Organization Nervous System Development Regulation Of Organelle Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Anatomical Structure Development Regulation Of Cellular Component Organization Regulation Of Cell Projection Organization System Development Multicellular Organismal Development Maintenance Of Cell Polarity Generation Of Neurons Actin Cytoskeleton Organization Developmental Process Neuron Projection Development Actin Filament Organization Actin Filament-based Process Neurogenesis Cytoskeleton Organization Cell Projection Organization Regulation Of Cell Projection Assembly Regulation Of Actin Cytoskeleton Organization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Neuron Development Protein Localization To Basolateral Plasma Membrane Locomotion Regulation Of Actin Filament-based Process Maintenance Of Epithelial Cell Apical/basal Polarity Organelle Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Cellular Protein Localization Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Cell Projection Organization Maintenance Of Apical/basal Cell Polarity Immune Response-activating Cell Surface Receptor Signaling Pathway Cellular Localization Actin Polymerization Or Depolymerization Neuron Differentiation Regulation Of Cell Morphogenesis Establishment Or Maintenance Of Cell Polarity Cell Differentiation Cell Development Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Differentiation Signaling Cellular Component Assembly Cell Communication Immune Response-regulating Cell Surface Receptor Signaling Pathway Axon Development Cell Morphogenesis
Tagcloud ?		acetylation address carbamylated cepo display e1a epigenetic epo erythropoietin gap43 implications interest issue markedly modifications neurites neuronal neurons neuropsychiatric p300 possibly potentiates psd95 regulate spine subsequent transactivation upregulation yet
Tagcloud (Difference) ?		acetylation address carbamylated cepo display e1a epigenetic epo erythropoietin gap43 implications interest issue markedly modifications neurites neuronal neurons neuropsychiatric p300 possibly potentiates psd95 regulate spine subsequent transactivation upregulation yet
Tagcloud (Intersection) ?