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PHLDA1 and HSPA4
Number of citations of the paper that reports this interaction (PMID
17024176
)
13
Data Source:
HPRD
(in vivo, in vitro)
PHLDA1
HSPA4
Gene Name
pleckstrin homology-like domain, family A, member 1
heat shock 70kDa protein 4
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Nucleolus
Plasma Membrane
Cytoplasmic Vesicle Membrane
Mitochondrion
Cytosol
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
ATP Binding
Biological Process
Apoptotic Process
Forebrain Neuron Differentiation
Positive Regulation Of Apoptotic Process
FasL Biosynthetic Process
Response To Unfolded Protein
Protein Import Into Mitochondrial Outer Membrane
Chaperone-mediated Protein Complex Assembly
Pathways
Drugs
Diseases
GWAS
Blood trace element (Cu levels) (
23720494
)
Protein-Protein Interactions
9 interactors:
APP
EIF3D
HSPA4
HSPA4L
KRTAP4-12
MDFI
PABPC4
PLSCR1
RPL14
58 interactors:
AGTRAP
APPBP2
BAG1
BAG2
BAG5
BRMS1
CALM1
CD40
CDC73
CDKN2A
CSNK1A1
CSNK2A1
DDIT4
DNAJB1
DUSP1
EGFR
ESR1
FANCC
FES
FKBP4
GATA1
GRPEL2
GSK3B
GZMA
HAP1
HDAC3
HNRNPD
HSPBP1
IKBKG
KPNA2
KRT18
MAPT
NFKB1
NR3C2
OLR1
PHLDA1
PPP1CA
PRKCB
PRKCD
PRKCG
PRSS23
PSMD10
RAF1
REL
RELA
SMAD3
SOD1
ST13
STIP1
STUB1
SUGT1
TERT
TIMM44
TOMM40
TRAF6
TTC1
UBE2L3
UBE3A
Entrez ID
22822
3308
HPRD ID
05625
09025
Ensembl ID
Uniprot IDs
Q8WV24
P34932
PDB IDs
Enriched GO Terms of Interacting Partners
?
Response To Stress
Blood Coagulation
Hemostasis
Synaptic Growth At Neuromuscular Junction
Formation Of Cytoplasmic Translation Initiation Complex
Regulation Of Body Fluid Levels
Wound Healing
Response To Unfolded Protein
Collateral Sprouting In Absence Of Injury
Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Translation
Response To Wounding
Protein Import Into Mitochondrial Outer Membrane
RNA Catabolic Process
Collateral Sprouting
Axon Midline Choice Point Recognition
Platelet Activation
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Phosphatidylserine Biosynthetic Process
Axon Choice Point Recognition
Membrane Organization
Gene Expression
Cytoplasmic Translational Initiation
Translational Initiation
Establishment Of Protein Localization To Membrane
Neuron Remodeling
Regulation Of Binding
Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway
Regulation Of Translation
Phospholipid Scrambling
Cytoplasmic Translation
Chaperone-mediated Protein Complex Assembly
Ribonucleoprotein Complex Biogenesis
Regulation Of Cell Death
Regulation Of Apoptotic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Signal Transduction
Regulation Of Cellular Protein Metabolic Process
Cellular Response To Organic Substance
Negative Regulation Of Cell Death
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Protein Metabolic Process
Response To Organic Substance
Regulation Of Signal Transduction
Neurotrophin TRK Receptor Signaling Pathway
Cell Death
Death
Neurotrophin Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Regulation Of Signaling
Negative Regulation Of Protein Metabolic Process
Positive Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Response To Stress
Cellular Response To Growth Factor Stimulus
Protein Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Apoptotic Process
Response To Growth Factor
Cellular Response To Stimulus
Programmed Cell Death
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Protein Modification Process
Negative Regulation Of Signal Transduction
Cellular Metabolic Process
Signaling
Response To Stimulus
Cell Communication
Regulation Of Metabolic Process
Negative Regulation Of Signaling
Positive Regulation Of Cell Death
Cellular Protein Metabolic Process
Signal Transduction
Regulation Of Protein Phosphorylation
Immune System Process
Regulation Of Catalytic Activity
Positive Regulation Of Cellular Biosynthetic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Tagcloud
?
competence
cumulus
damaged
domestic
fertility
hfs2
hsf
hsf1
hsp110
hsp40
hsp90a
hsp90b
hsph1
hsps
machinery
oocyte
oocytes
operational
ovaries
ovary
pig
preserve
sows
summer
unexpectedly
warm
winter
Tagcloud (Difference)
?
competence
cumulus
damaged
domestic
fertility
hfs2
hsf
hsf1
hsp110
hsp40
hsp90a
hsp90b
hsph1
hsps
machinery
oocyte
oocytes
operational
ovaries
ovary
pig
preserve
sows
summer
unexpectedly
warm
winter
Tagcloud (Intersection)
?