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STX11 and SMARCE1
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
STX11
SMARCE1
Description
syntaxin 11
SWI/SNF related BAF chromatin remodeling complex subunit E1
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Apparatus
Plasma Membrane
Endomembrane System
Membrane
SNARE Complex
Presynaptic Active Zone Membrane
Nuclear Chromosome
Kinetochore
Chromatin
Nucleus
Nucleoplasm
Nuclear Matrix
SWI/SNF Complex
RSC-type Complex
Protein-containing Complex
Brahma Complex
NpBAF Complex
NBAF Complex
BBAF Complex
Molecular Function
SNARE Binding
SNAP Receptor Activity
Protein Binding
DNA Binding
Chromatin Binding
Transcription Coactivator Activity
RNA Binding
Protein Binding
N-acetyltransferase Activity
Nuclear Receptor Binding
Nucleosomal DNA Binding
Biological Process
Intracellular Protein Transport
Exocytosis
Protein Transport
Vesicle-mediated Transport
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Vesicle Docking
Membrane Fusion
Chromatin Organization
Nucleosome Disassembly
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Neurogenesis
Regulation Of Mitotic Metaphase/anaphase Transition
Positive Regulation Of T Cell Differentiation
Positive Regulation Of Cell Differentiation
Positive Regulation Of Myoblast Differentiation
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of DNA-templated Transcription
Regulation Of G0 To G1 Transition
Positive Regulation Of Stem Cell Population Maintenance
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Double-strand Break Repair
Regulation Of Nucleotide-excision Repair
Pathways
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of MITF-M-dependent genes involved in pigmentation
Regulation of MITF-M-dependent genes involved in pigmentation
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Formation of the canonical BAF (cBAF) complex
Formation of the polybromo-BAF (pBAF) complex
Formation of the embryonic stem cell BAF (esBAF) complex
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Phenethyl Isothiocyanate
Diseases
Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS
Nicotine dependence symptom count (
25555482
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Allergic disease (asthma, hay fever and/or eczema) (age of onset) (
32603359
)
Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) (
32603359
)
Allergic disease (asthma, hay fever or eczema) (
29083406
29785011
)
Allergic rhinitis (
31361310
)
Asthma (
30929738
31619474
31959851
)
Asthma (childhood onset) (
30929738
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Eczema (
31361310
)
Triglyceride levels in HIV infection (
33109212
)
Interacting Genes
98 interacting genes:
AIRIM
APP
AXIN1
AXIN2
BLOC1S6
BYSL
CARD9
CCBE1
CCDC120
CCDC125
CCDC184
CCDC196
CCDC33
CCHCR1
CCNK
CDCA7L
CDR2L
CRYBA4
CTBP2
CWF19L2
DISC1
DUSP29
EIF1AD
EIF2B5
FAM110A
FAM161A
FAM161B
FAM74A4
FAM90A1
FARS2
GOLGA8EP
GOLGA8F
HAUS1
HGS
HOXA1
IKBKG
IKZF3
KAT5
KCTD9
KDM1A
KIFC3
KLC3
KRT75
KXD1
LENG1
LONRF1
MAGOHB
MBD3L1
MBIP
MEOX2
MFAP1
MID2
MIS18A
MTCL2
NDC80
NTAQ1
PKN1
PPP1R18
PRKAB2
PRPF18
PRPF31
PSMA3
PSMC3
RAD51D
RNF6
RNF8
RNPS1
RUNX1T1
SCNM1
SH2D4A
SHC3
SIKE1
SLC38A2
SMARCE1
SNAP23
SNAP25
SNCA
SNX3
STX1A
STX4
SUV39H1
TADA3
TAF6L
TBK1
TCEA2
TCF4
TLE5
TNFRSF21
TRIM41
TSGA10IP
UBASH3A
USHBP1
VAMP2
VPS52
ZCCHC10
ZNF19
ZNF417
ZNF587
94 interacting genes:
AMOTL2
AR
ARID2
BAZ1B
BRAP
BRMS1
CCDC136
CCDC172
CCDC183
CCHCR1
CDR2
CEBPA
CEP170P1
CEP63
CEP70
CYSRT1
DISC1
EPS8
ERG
ESR1
ESR2
EXOC4
EXOC7
FAM217B
FSD2
GATA1
GOLGA2
GOLGA6L9
GRIPAP1
HUNK
IFT74
IFT88
ING5
ITCH
JAKMIP2
KIFC3
KLF1
KRT14
KRT15
KRT16
KRT19
KRT27
KRT31
KRT34
KRT35
KRT37
KRT39
KRT40
KRTAP1-1
KRTAP10-8
KRTAP10-9
KRTAP6-3
MDM2
MED4
MEOX2
MIPOL1
MRFAP1L1
MTUS2
NBPF22P
NCOA1
NCOA2
NCOA3
NOTCH2NLA
NR0B2
NR3C1
NUP62
OGT
OIP5
PGR
PSMC6
RALBP1
RARB
RCOR1
RELB
RINT1
RSPH1
SIN3A
SIN3B
SMAD1
SMARCA4
SPAG5
SRC
STX11
SYCE1
TEX12
TFE3
TFIP11
TIAM1
TNIK
TRIM54
TRIP10
TXLNA
USHBP1
VPS52
Entrez ID
8676
6605
HPRD ID
09231
04382
Ensembl ID
ENSG00000135604
ENSG00000073584
Uniprot IDs
O75558
Q969G3
PDB IDs
6LTH
6LTJ
7CYU
7VDV
7Y8R
Enriched GO Terms of Interacting Partners
?
Identical Protein Binding
Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex
SNARE Complex Assembly
Protein Binding
SNAP Receptor Activity
SNARE Complex
Synaptic Vesicle Docking
Synaptic Vesicle Exocytosis
SNARE Binding
Regulation Of Cellular Response To Stress
Regulation Of DNA Repair
BLOC-1 Complex
Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex
Synaptic Vesicle Priming
Establishment Of Localization In Cell
Membrane Docking
Establishment Of Organelle Localization
Positive Regulation Of Proteolysis
Positive Regulation Of Synaptic Transmission
Syntaxin Binding
Synaptobrevin 2-SNAP-25-syntaxin-1a Complex
Regulation Of RNA Metabolic Process
Transcription Coactivator Activity
Neurotransmitter Transport
Vesicle Fusion
Membrane Fusion
Long-term Synaptic Potentiation
Regulation Of Gene Expression
Organelle Membrane Fusion
Organelle Localization
Establishment Of Vesicle Localization
Host-mediated Perturbation Of Symbiont Process
DNA Repair-dependent Chromatin Remodeling
Regulation Of DNA-templated Transcription
Nuclear Androgen Receptor Binding
Vesicle Organization
Vesicle Docking
Regulation Of RNA Biosynthetic Process
Regulation Of Macromolecule Biosynthetic Process
Modulation Of Process Of Another Organism
Microtubule-based Process
Vesicle Localization
Neuron Projection
Nucleoplasm
Keratin Filament
Intermediate Filament
Structural Constituent Of Skin Epidermis
Intermediate Filament Organization
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Nuclear Receptor-mediated Signaling Pathway
Morphogenesis Of An Epithelium
Cytoskeleton
Tissue Morphogenesis
Estrogen Response Element Binding
Chromatin
Structural Molecule Activity
Protein Binding
Intracellular Receptor Signaling Pathway
Cytoskeleton Organization
Organelle Organization
Hormone-mediated Signaling Pathway
Steroid Hormone Receptor Signaling Pathway
Nuclear Receptor-mediated Steroid Hormone Signaling Pathway
Chromatin Binding
Steroid Binding
Nuclear Receptor Activity
Supramolecular Fiber Organization
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Epithelial Cell Differentiation
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Intracellular Signal Transduction
Anatomical Structure Morphogenesis
Cellular Developmental Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Nuclear Steroid Receptor Activity
Sin3-type Complex
Estrogen Receptor Signaling Pathway
Positive Regulation Of Stem Cell Population Maintenance
Cytosol
Positive Regulation Of RNA Metabolic Process
Epidermis Development
Cell Differentiation
DNA-binding Transcription Factor Activity
Protein-containing Complex
Cellular Response To Hormone Stimulus
Negative Regulation Of Transcription By RNA Polymerase II
Nucleoplasm
Developmental Process
Transcription Repressor Complex
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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