OSGIN1 and MTERF4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		OSGIN1	MTERF4
Description		oxidative stress induced growth inhibitor 1	mitochondrial transcription termination factor 4
Image		No pdb structure
GO Annotations	Cellular Component	Midbody	Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Monooxygenase Activity Protein Binding Growth Factor Activity Oxidoreductase Activity	Nucleic Acid Binding RNA Binding Protein Binding RRNA Binding
	Biological Process	Signal Transduction Cell Differentiation Negative Regulation Of Cell Growth	RRNA Processing Mitochondrial Transcription Protein Targeting To Mitochondrion Heart Development Ribosome Assembly Camera-type Eye Development Mitochondrial Ribosome Assembly Regulation Of Mitochondrial Transcription
Pathways			rRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) LDL cholesterol ( 30275531) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Pursuit maintenance gain ( 29064472) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		47 interacting genes: AKT1 ARNT2 ATM BCAR3 BEND7 BTBD2 CAPN3 CCDC33 CENPN CRX DECR2 DNAJA3 FGFR4 GCLM HOMEZ IKBKG IKZF3 INCA1 KATNBL1 KRAS KRT75 LNX1 MEI4 MEIS2 MEOX1 MEOX2 MTERF4 PAX5 PDE4A PDE4C PICK1 POLDIP3 POLR2G PPM1D PTEN REL SAXO1 SMARCB1 SORBS3 TCF12 TCF4 TLE5 TRIM54 XRCC3 ZBTB42 ZC2HC1C ZKSCAN4	11 interacting genes: APP ATXN1 BANP CIDEB CRYAA DGAT2L6 EMD FOS OSGIN1 TNFRSF10D UBC
Entrez ID		29948	130916
HPRD ID		06412	14699
Ensembl ID		ENSG00000140961	ENSG00000122085
Uniprot IDs		Q9UJX0	B4DFP7 Q7Z6M4
PDB IDs			4FP9 4FZV 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF3 7OF5 7OF7 7OIC 7PD3 8PK0 8QSJ
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Gene Expression Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Protein-containing Complex Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process Protein Binding DNA Binding Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Somite Specification Positive Regulation Of Metabolic Process Chromatin Regulation Of Metabolic Process Nervous System Development Activation-induced Cell Death Of T Cells Identical Protein Binding Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Developmental Process Response To Nitrosative Stress Positive Regulation Of Proteolysis CAMP Catabolic Process Regulation Of Cell Communication Regulation Of Signaling System Development Regulation Of Cell Population Proliferation Anoikis HMG Box Domain Binding Nucleus Embryonic Pattern Specification Cyclic Nucleotide Catabolic Process Myelin Maintenance Nucleoplasm Positive Regulation Of Intracellular Signal Transduction Segment Specification	Response To Light Stimulus Associative Learning Memory Learning Response To Radiation Amyloid Fibril Formation Amyloid-beta Complex Growth Cone Lamellipodium Visual Behavior Regulation Of Response To Calcium Ion Learning Or Memory Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To Growth Factor Stimulus Visual Learning Identical Protein Binding TMEM240-body Skeletal Muscle Cell Differentiation Medium-term Memory Cellular Response To Prolactin Acetylcholine Receptor Activator Activity PTB Domain Binding Apoptotic Process Cognition Adult Locomotory Behavior Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Response To Growth Factor Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle System Process Endoplasmic Reticulum Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Nervous System Process Response To Prolactin Conditioned Taste Aversion Acylglycerol Acyl-chain Remodeling Programmed Cell Death Cell Death Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus
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