FOXP2 and TSACC

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FOXP2	TSACC
Gene Name		forkhead box P2	TSSK6 activating co-chaperone
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity	Chaperone Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Mesenchymal Cell Proliferation Transcription, DNA-templated Skeletal Muscle Tissue Development Post-embryonic Development Cerebellum Development Caudate Nucleus Development Putamen Development Cerebral Cortex Development Growth Vocal Learning Camera-type Eye Development Negative Regulation Of Transcription, DNA-templated Lung Alveolus Development Smooth Muscle Tissue Development Righting Reflex Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 22936669)
Protein-Protein Interactions		13 interactors: AES CCNC CTBP1 CTBP2 FAM124A FOXP1 FOXP4 MAPK3 PIN1 RPIA SDCBP SP4 TSACC	3 interactors: DTNB FOXP2 KDM1A
Entrez ID		93986	128229
HPRD ID		05611	10252
Ensembl ID		ENSG00000128573	ENSG00000163467
Uniprot IDs		B7ZLK5 O15409 Q8N6B5 Q8N6B6	Q96A04
PDB IDs		2A07 2AS5
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Lung Goblet Cell Differentiation Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Lung Secretory Cell Differentiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Transcription From RNA Polymerase II Promoter White Fat Cell Differentiation Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Viral Genome Replication Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Epithelial Cell Differentiation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Regulation Of Binding Negative Regulation Of Biosynthetic Process Regulation Of Histone Acetylation Positive Regulation Of Metabolic Process Biosynthetic Process Negative Regulation Of Protein Binding Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Lung Epithelial Cell Differentiation Lung Cell Differentiation Lung Epithelium Development Interleukin-21 Secretion Negative Regulation Of Apolipoprotein Binding Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Positive Regulation Of Histone Modification Regulation Of Organelle Organization Axon Guidance Regulation Of Signal Transduction Response To Interleukin-1 Positive Regulation Of Organelle Organization	Positive Regulation Of Stem Cell Proliferation Regulation Of Stem Cell Proliferation Putamen Development Caudate Nucleus Development Regulation Of Primitive Erythrocyte Differentiation Forebrain Development Vocal Learning Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Muscle Structure Development Righting Reflex Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Positive Regulation Of Megakaryocyte Differentiation Auditory Behavior Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Brain Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Head Development Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Cell Proliferation Striatum Development Granulocyte Differentiation Mechanosensory Behavior Response To Auditory Stimulus Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Positive Regulation Of Erythrocyte Differentiation Central Nervous System Development Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Reflex Regulation Of Histone H3-K4 Methylation Subpallium Development Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Transcription, DNA-templated Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Hormone Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Smooth Muscle Tissue Development Histone Lysine Demethylation Regulation Of Hormone Metabolic Process Histone Demethylation Regulation Of Erythrocyte Differentiation
Tagcloud ?		20p12 21q22 22q13 42e 6p21 7q31 aif1 ancestry cd crohn cumulative ep300 european exerted genotyped gwas ifngr2 intergenic likelihood loci macrod2 rbx1 representing rs4820425 southern spain suggestive top undiscovered
Tagcloud (Difference) ?		20p12 21q22 22q13 42e 6p21 7q31 aif1 ancestry cd crohn cumulative ep300 european exerted genotyped gwas ifngr2 intergenic likelihood loci macrod2 rbx1 representing rs4820425 southern spain suggestive top undiscovered
Tagcloud (Intersection) ?