INO80E and TNFAIP8

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		INO80E	TNFAIP8
Description		INO80 complex subunit E	TNF alpha induced protein 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Ino80 Complex	Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process	Telomere Maintenance Regulation Of DNA Replication DNA Repair Regulation Of DNA Repair DNA Recombination Chromatin Remodeling DNA Damage Response Regulation Of Chromosome Organization Positive Regulation Of DNA Repair Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Cycle Regulation Of DNA Strand Elongation Positive Regulation Of Telomere Maintenance In Response To DNA Damage	Apoptotic Process Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process
Pathways		UCH proteinases DNA Damage Recognition in GG-NER	PI Metabolism
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 25673413) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Schizophrenia ( 25056061 28991256 29483656)	A body shape index ( 34021172) Allergic disease (asthma, hay fever or eczema) ( 29083406) Apolipoprotein A1 levels ( 32203549) Asthma ( 32296059 31959851 31619474 31361310) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) HDL cholesterol levels in HIV infection ( 33109212) Heschl's gyrus morphology ( 25130324) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Lymphocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 31604244) Plantar fascial disorders ( 29534260) Pyoderma gangrenosum in inflammatory bowel disease ( 24487271) Triglyceride levels ( 32154731 32203549) Triglycerides ( 30275531) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971 28552196) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412) White blood cell count ( 32888494)
Interacting Genes		21 interacting genes: APPL1 CDC23 CRK FAM124A FAM161A GEM IKBKG KPNA2 LNX1 MAB21L3 MORN4 NHLH1 PHF19 PICK1 PIN1 PRKAA1 PSMA1 SDCBP TBRG1 TLE5 TNFAIP8	11 interacting genes: ATN1 EAF1 EAPP INO80E MED4 PLEKHF1 PLEKHF2 PRR13 SDCBP TIFA TMEM132D
Entrez ID		283899	25816
HPRD ID		08816	18204
Ensembl ID		ENSG00000169592	ENSG00000145779
Uniprot IDs		J3KNE2 Q8NBZ0	B3KUI2 O95379
PDB IDs
Enriched GO Terms of Interacting Partners?			Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation
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