GABPB1 and ADGRB2

Number of citations of the paper that reports this interaction (PubMedID 16412436)
0

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		GABPB1	ADGRB2
Description		GA binding protein transcription factor subunit beta 1	adhesion G protein-coupled receptor B2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasmic Ribonucleoprotein Granule	Extracellular Region Plasma Membrane Membrane Synapse Glutamatergic Synapse
	Molecular Function	Transcription Cis-regulatory Region Binding Protein Binding	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Mitochondrion Organization Positive Regulation Of Transcription By RNA Polymerase II	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Peripheral Nervous System Development Negative Regulation Of Angiogenesis Calcineurin-NFAT Signaling Cascade Positive Regulation Of Synapse Assembly
Pathways
Drugs
Diseases
GWAS		Superior frontal gyrus volume ( 31530798)	Asthma ( 31959851) Intraocular pressure ( 29617998 29785010) Smoking status (ever vs never smokers) ( 30643258) Walking pace ( 33128006)
Interacting Genes		30 interacting genes: ADGRB2 ATF1 BAIAP2L2 CEBPA CIC EP300 FAM90A1 FANCG GABPA HCFC1 IL16 LMO1 LMO3 LMO4 MAGEB18 MED20 POGZ RBM11 RSPH14 RYBP SNRPA SNRPB2 SNW1 TDRD7 TRAF2 TRIM55 TRIM63 USO1 YAF2 ZDHHC17	9 interacting genes: ARHGAP1 DLG4 GABPB1 HDHD2 LRP2BP SHANK1 SHANK2 SNTA1 STARD13
Entrez ID		2553	576
HPRD ID		15975	04063
Ensembl ID		ENSG00000104064	ENSG00000121753
Uniprot IDs		Q06547	A2A3C1 O60241
PDB IDs			8OEK
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Binding Transcription Coactivator Activity Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Transcription Coregulator Activity Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Spliceosomal SnRNP Complex Nucleoplasm Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression U1 SnRNA Binding Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Nucleus STAT Family Protein Binding TORC2 Signaling Positive Regulation Of Metabolic Process Host-mediated Activation Of Viral Transcription Chromatin DNA Binding U1 SnRNP Transcription Corepressor Activity Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Intracellular Signaling Cassette Histone Acetyltransferase Complex Transcription Regulator Complex Regulation Of Protein-containing Complex Assembly Nuclear Speck Nuclear Androgen Receptor Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Host-mediated Perturbation Of Viral Transcription RNA Polymerase II Transcription Regulator Complex Chromatin Binding Negative Regulation Of Biosynthetic Process	Vocalization Behavior Ionotropic Glutamate Receptor Binding Learning Synaptic Receptor Adaptor Activity Social Behavior Learning Or Memory Associative Learning Cognition SH3 Domain Binding Dendritic Spine Morphogenesis Dendritic Spine Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Ionotropic Glutamate Receptor Signaling Pathway Excitatory Synapse Positive Regulation Of Excitatory Postsynaptic Potential Dendritic Spine Organization Ligand-gated Ion Channel Signaling Pathway Neuron Projection Organization Postsynapse Organization Postsynaptic Membrane Neuromuscular Process Controlling Balance Modulation Of Excitatory Postsynaptic Potential Glutamate Receptor Signaling Pathway Postsynaptic Density Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Migration Involved In Sprouting Angiogenesis P2Y1 Nucleotide Receptor Binding Protein Localization To Synapse Determination Of Affect Somatostatin Receptor Binding Scaffold Protein Binding Negative Regulation Of Endothelial Cell Migration Neuron Projection Neuromuscular Junction Protein Localization To Cell Junction PDZ Domain Binding Endothelial Tube Lumen Extension System Process Negative Regulation Of Endocytic Recycling Beta-1 Adrenergic Receptor Binding Regulation Of Grooming Behavior Nervous System Process Lactose Synthase Activity Structural Constituent Of Postsynaptic Density Regulation Of Nervous System Process Regulation Of Membrane Potential Neuromuscular Process Syntrophin Complex N-acetyllactosamine Synthase Activity Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity
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