GABPB1 and ATF1

Number of citations of the paper that reports this interaction (PMID 10585419)
6

Data Source:
HPRD (in vitro)

		GABPB1	ATF1
Gene Name		GA binding protein transcription factor, beta subunit 1	activating transcription factor 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm ATF1-ATF4 Transcription Factor Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Complex Binding Protein Heterodimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Organelle Organization Mitochondrion Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter	Toll-like Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Positive Regulation Of Neuron Projection Development Response To Organic Cyclic Compound Response To Cobalt Ion Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Toll-like Receptor 10 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Cellular Protein Complex Assembly Innate Immune Response Positive Regulation Of DNA Replication Positive Regulation Of Transcription From RNA Polymerase II Promoter Neurotrophin TRK Receptor Signaling Pathway Stress-activated MAPK Cascade
Pathways			CREB phosphorylation Toll Like Receptor 7/8 (TLR7/8) Cascade CREB phosphorylation Toll Like Receptor TLR6:TLR2 Cascade Activated TLR4 signalling Toll Like Receptor TLR1:TLR2 Cascade MyD88 cascade initiated on plasma membrane Toll Like Receptor 5 (TLR5) Cascade MyD88 dependent cascade initiated on endosome TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation MyD88:Mal cascade initiated on plasma membrane Toll Like Receptor 9 (TLR9) Cascade Innate Immune System Signalling by NGF TRIF-mediated TLR3/TLR4 signaling MAP kinase activation in TLR cascade NGF signalling via TRKA from the plasma membrane MyD88-independent cascade Toll Like Receptor 2 (TLR2) Cascade Toll-Like Receptors Cascades Toll Like Receptor 10 (TLR10) Cascade Toll Like Receptor 3 (TLR3) Cascade Toll Like Receptor 4 (TLR4) Cascade MAPK targets/ Nuclear events mediated by MAP kinases Nuclear Events (kinase and transcription factor activation)
Drugs
Diseases
GWAS			Colorectal cancer ( 20972440) Sudden cardiac arrest ( 21658281)
Protein-Protein Interactions		23 interactors: ATF1 BAI2 CIC FAM90A1 FANCG GABPA HCFC1 IL16 LMO1 LMO3 LMO4 MAGEB18 POGZ RBM11 RSPH14 RYBP SNRPA SNRPB2 TDRD7 TRAF2 USO1 YAF2 ZDHHC17	20 interactors: BRCA1 CAMK1 CAMK2A CAMK2G CREB1 CREBBP CREM CSNK2A1 CSNK2A2 CSNK2B EDF1 GABPA GABPB1 HNF1B JUN PRKACA RPS6KA4 RPS6KA5 SPI1 SRA1
Entrez ID		2553	466
HPRD ID		15975	00440
Ensembl ID		ENSG00000104064	ENSG00000123268
Uniprot IDs		Q06547	P18846
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Cellular Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Release From Viral Latency Golgi Vesicle Docking Regulation Of Metabolic Process Toll-like Receptor 4 Signaling Pathway Biosynthetic Process Cellular Protein Complex Assembly RNA Splicing Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Toll-like Receptor Signaling Pathway Mitochondrion Organization Negative Regulation Of Megakaryocyte Differentiation MRNA Processing Transcription From RNA Polymerase II Promoter Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction	Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Developmental Process Multicellular Organismal Development Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Chromosome Organization Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Anatomical Structure Development Protein Phosphorylation Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Regulation Of Histone Acetylation Phosphorylation Response To Cytokine RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Protein Modification Process Axon Development Regulation Of Myeloid Cell Differentiation Gene Expression Chemotaxis Positive Regulation Of Histone Acetylation Negative Regulation Of Gene Expression Nervous System Development Cell Development Cellular Macromolecule Biosynthetic Process Axon Guidance Apoptotic Process Positive Regulation Of Peptidyl-lysine Acetylation Negative Regulation Of Chromosome Organization Macromolecule Biosynthetic Process Positive Regulation Of Protein Acetylation Programmed Cell Death Anatomical Structure Morphogenesis
Tagcloud ?		arsenic as1 cadmium capabilities cdkn2b chemical coding cycloheximide ethical flj33630 hipscs ideal indicators linc00152 linc0541471 lncrnas mir22hg mrnas peroxide pervasive pluripotent possess renewal responded rnas stresses surrogate toxicological v2	cascades creb erk2 ester esters exclude fgf k1 k2 km mapk2 mapkap mc mirror msk1 ngf p90rsk pc12 phorbol phosphorylates pka polypeptide ro sapk2 sb ser133 sk suppresses unstimulated
Tagcloud (Difference) ?		arsenic as1 cadmium capabilities cdkn2b chemical coding cycloheximide ethical flj33630 hipscs ideal indicators linc00152 linc0541471 lncrnas mir22hg mrnas peroxide pervasive pluripotent possess renewal responded rnas stresses surrogate toxicological v2	cascades creb erk2 ester esters exclude fgf k1 k2 km mapk2 mapkap mc mirror msk1 ngf p90rsk pc12 phorbol phosphorylates pka polypeptide ro sapk2 sb ser133 sk suppresses unstimulated
Tagcloud (Intersection) ?