FANCB and FANCL

Number of citations of the paper that reports this interaction (PMID 16720839)
25

Data Source:
BioGRID (two hybrid, two hybrid)

		FANCB	FANCL
Gene Name		Fanconi anemia, complementation group B	Fanconi anemia, complementation group L
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Fanconi Anaemia Nuclear Complex	Nuclear Envelope Nucleoplasm Cytoplasm Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity
	Biological Process	DNA Repair	DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Gamete Generation Regulation Of Cell Proliferation
Pathways		Fanconi Anemia pathway	Fanconi Anemia pathway
Drugs
Diseases
GWAS			Body mass index ( 20935630) Obesity ( 23563607)
Protein-Protein Interactions		3 interactors: C17orf70 F3 FANCL	24 interactors: ACVR1 BMPR1B C17orf70 CCDC36 CHCHD3 DOCK8 EIF4ENIF1 FANCB FANCD2 FANCI GGN GRN HES1 IKZF3 KIFC3 LZTS2 PCNA RBM45 RIMBP3 SSX2IP TFCP2 TGFBR1 UBE2T UBE2W
Entrez ID		2187	55120
HPRD ID		06557	06997
Ensembl ID		ENSG00000181544	ENSG00000115392
Uniprot IDs		Q8NB91	B5MC31 B5MCZ6 Q9NW38
PDB IDs			3ZQS
Enriched GO Terms of Interacting Partners?		Activation Of Plasma Proteins Involved In Acute Inflammatory Response Activation Of Blood Coagulation Via Clotting Cascade Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Blood Coagulation, Extrinsic Pathway DNA Repair Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Response To Stress Cellular Response To DNA Damage Stimulus Positive Regulation Of Positive Chemotaxis Positive Regulation Of Blood Coagulation Positive Regulation Of Coagulation Protein Monoubiquitination DNA Metabolic Process Positive Regulation Of Wound Healing	Pharyngeal System Development DNA Repair Cellular Response To DNA Damage Stimulus DNA Metabolic Process Single Organism Reproductive Process Pathway-restricted SMAD Protein Phosphorylation Response To Stress Reproductive Process Mesenchymal Cell Development Protein K11-linked Ubiquitination Epithelial Cell Fate Commitment Gamete Generation Mesenchymal Cell Differentiation Movement Of Cell Or Subcellular Component Activin Receptor Signaling Pathway Cellular Response To Stress Urogenital System Development Cellular Response To Stimulus Sexual Reproduction Multicellular Organismal Reproductive Process Positive Regulation Of Bone Mineralization Protein Monoubiquitination Positive Regulation Of Biomineral Tissue Development Multicellular Organism Reproduction Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Pattern Specification Process Mesenchyme Development Regulation Of Transcription From RNA Polymerase II Promoter Peptidyl-threonine Phosphorylation In Utero Embryonic Development Nucleobase-containing Compound Metabolic Process Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Positive Regulation Of Deoxyribonuclease Activity Pharyngeal Arch Artery Morphogenesis Memory T Cell Proliferation Lateral Inhibition Endocardial Cushion Cell Fate Commitment Cell Cycle Heart Morphogenesis Heart Development Smooth Muscle Cell Differentiation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Artery Morphogenesis Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cardiac Septum Morphogenesis Thymus Development Stem Cell Development Heterocycle Metabolic Process
Tagcloud ?			2p16 2q24 4p15 agencies assisting epilepsies epilepsy ethnically filtering generalised governmental grouping harbouring heritability ie implicating imputation league lumping pcdh7 phenotyped philanthropic pleiotropically protocadherin scn1a splitting standardised unclassified vrk2
Tagcloud (Difference) ?			2p16 2q24 4p15 agencies assisting epilepsies epilepsy ethnically filtering generalised governmental grouping harbouring heritability ie implicating imputation league lumping pcdh7 phenotyped philanthropic pleiotropically protocadherin scn1a splitting standardised unclassified vrk2
Tagcloud (Intersection) ?