FANCB and FAAP100

Number of citations: 42 (PubMedID 17396147)
Data Source: HPRD (two hybrid, in vivo)

		FANCB	FAAP100
Name		FA complementation group B	FA core complex associated protein 100
Structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Fanconi Anaemia Nuclear Complex	Chromatin Nucleus Nucleoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding	DNA Binding Protein Binding
	Biological Process	DNA Repair DNA Damage Response Interstrand Cross-link Repair Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Replication-born Double-strand Break Repair Via Sister Chromatid Exchange Negative Regulation Of Double-strand Break Repair Via Homologous Recombination	DNA Repair DNA Damage Response Interstrand Cross-link Repair
Pathways		Fanconi Anemia Pathway PKR-mediated signaling	Fanconi Anemia Pathway PKR-mediated signaling
Diseases		Fanconi anemia	None
GWAS		No GWAS studies recorded	No GWAS studies recorded
Novel Interactors		None recorded	1 novel interactors: CYGB
Interacting Genes		5 interacting genes: CFTR F3 FAAP100 FANCF FANCL	10 interacting genes: APP ATRIP CFTR FANCB FANCF FANCL HOXA1 LINC00839 MDFI PTGES3L-AARSD1
Entrez ID		2187	80233
HPRD ID		06557	07982
Ensembl ID		ENSG00000181544	ENSG00000185504
Uniprot IDs		A0A8Q3WL66 C9J5X9 Q8NB91	A4ZI32 Q0VG06
PDB IDs		7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV	7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV
GO Terms Enriched among Interactors		Fanconi Anaemia Nuclear Complex Interstrand Cross-link Repair Response To Stress Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Activation Of Plasma Proteins Involved In Acute Inflammatory Response DNA Repair Cellular Response To Stress Positive Regulation Of Anion Channel Activity Activation Of Blood Coagulation Via Clotting Cascade Serine-type Peptidase Complex Positive Regulation Of Monoatomic Anion Transport DNA Metabolic Process DNA Damage Response Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Chromatin Regulation Of Body Fluid Levels Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Water Transport Bicarbonate Transport Positive Regulation Of Blood Coagulation Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Positive Chemotaxis Positive Regulation Of Endothelial Cell Apoptotic Process	Fanconi Anaemia Nuclear Complex Interstrand Cross-link Repair Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Visual Behavior Regulation Of Response To Calcium Ion Response To Stress Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To CAMP Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Cellular Response To Stress Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport DNA Metabolic Process DNA Repair DNA Damage Response Semicircular Canal Formation Abducens Nerve Formation Optokinetic Behavior ATR-ATRIP Complex Negative Regulation Of Hepatic Stellate Cell Activation Nitric Oxide Catabolic Process Catalase Activity Fatty Acid Peroxidase Activity Nitric Oxide Dioxygenase Activity, Heme Protein As Donor Carbon Monoxide Binding Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Enamel Mineralization Superoxide Dismutase Activity