FANCB

Name	FA complementation group B
Structure
Interactors	5 interactors: CFTR F3 FAAP100 FANCF FANCL
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding
	Biological Process	DNA Repair DNA Damage Response Interstrand Cross-link Repair Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Replication-born Double-strand Break Repair Via Sister Chromatid Exchange Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways	Fanconi Anemia Pathway PKR-mediated signaling
Diseases	Fanconi anemia
GWAS	No GWAS studies recorded
Entrez ID	2187
HPRD ID	06557
Ensembl ID	ENSG00000181544
Uniprot IDs	A0A8Q3WL66 C9J5X9 Q8NB91
PDB IDs	7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV
GO Terms Enriched among Interactors ?	Fanconi Anaemia Nuclear Complex Interstrand Cross-link Repair Response To Stress Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Activation Of Plasma Proteins Involved In Acute Inflammatory Response DNA Repair Cellular Response To Stress Positive Regulation Of Anion Channel Activity Activation Of Blood Coagulation Via Clotting Cascade Serine-type Peptidase Complex Positive Regulation Of Monoatomic Anion Transport DNA Metabolic Process DNA Damage Response Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Chromatin Regulation Of Body Fluid Levels Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Water Transport Bicarbonate Transport Positive Regulation Of Blood Coagulation Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Positive Chemotaxis Positive Regulation Of Endothelial Cell Apoptotic Process