ETFA and FAH

Data Source: HiPPIP (Novel)

		ETFA	FAH
Name		electron transfer flavoprotein subunit alpha	fumarylacetoacetate hydrolase
Structure			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Electron Transfer Flavoprotein Complex	Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Electron Transfer Activity Oxidoreductase Activity Flavin Adenine Dinucleotide Binding	Catalytic Activity Fumarylacetoacetase Activity Protein Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Amino Acid Catabolic Process Respiratory Electron Transport Chain Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase	L-arginine Catabolic Process L-phenylalanine Catabolic Process L-tyrosine Catabolic Process Lipid Metabolic Process Aromatic Amino Acid Metabolic Process Homogentisate Catabolic Process
Pathways		Respiratory electron transport	Tyrosine catabolism
Drugs		None	Fumaric acid Acetoacetic acid 4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid
Diseases		Glutaric acidemia; Glutaric acidemia, type I (GA1); Glutaric acidemia, type II (GA2); Multiple acyl coenzyme A dehydrogenase deficiency	Tyrosinemia; Tyrosinemia, type I; Tyrosinemia, type II; Tyrosinemia, type III; Hawkinsinuria
GWAS		Diverticular disease ( 30177863 ) Glioma ( 28346443 ) Heel bone mineral density ( 30598549 ) Non-glioblastoma glioma ( 26424050 28346443 ) Response to tocilizumab in rheumatoid arthritis ( 22491018 )	Blood protein levels ( 30072576 )
Novel Interactors		10 novel interactors: BNC1 CHRNA3 COX7C CSK CYP11A1 FAH LINC00597 MOV10L1 TNFRSF11A VCAM1	1 novel interactors: ETFA
Interacting Genes		7 interacting genes: CDC42 CFTR ETFB FBXL17 HSPB2 PSEN1 VHL	9 interacting genes: ADAMTSL4 CHRDL2 EGFR KRTAP10-8 KRTAP13-3 KRTAP5-9 PLEKHF2 SERTAD1 TCF4
Entrez ID		2108	2184
HPRD ID		01979	02040
Ensembl ID		ENSG00000140374	ENSG00000103876
Uniprot IDs		A0A0S2Z3L0 P13804	A0A384P5L6 P16930
PDB IDs		1EFV 1T9G 2A1T 2A1U	Not available
GO Terms Enriched among Interactors		None	Intermediate Filament