ETFA and ETFB

Number of citations of the paper that reports this interaction (PMID 22939629)
44

Data Source:
BioGRID (biochemical)
HPRD (in vivo)

		ETFA	ETFB
Gene Name		electron-transfer-flavoprotein, alpha polypeptide	electron-transfer-flavoprotein, beta polypeptide
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Extracellular Vesicular Exosome	Mitochondrion Mitochondrial Matrix Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Electron Carrier Activity Oxidoreductase Activity Flavin Adenine Dinucleotide Binding	Electron Carrier Activity
	Biological Process	Respiratory Electron Transport Chain Cellular Metabolic Process Small Molecule Metabolic Process	Respiratory Electron Transport Chain Cellular Metabolic Process Small Molecule Metabolic Process
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs
Diseases
GWAS		Response to tocilizumab in rheumatoid arthritis ( 22491018)
Protein-Protein Interactions		3 interactors: CDC42 ETFB PSEN1	2 interactors: APP ETFA
Entrez ID		2108	2109
HPRD ID		01979	00557
Ensembl ID		ENSG00000140374	ENSG00000105379
Uniprot IDs		P13804	P38117
PDB IDs		1EFV 1T9G 2A1T 2A1U	1EFV 1T9G 2A1T 2A1U
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Skin Morphogenesis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Canonical Wnt Signaling Pathway Myeloid Leukocyte Differentiation Regulation Of Protein Binding Cajal-Retzius Cell Differentiation Beta-amyloid Formation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Hair Follicle Cell Proliferation Skin Development Regulation Of Neuron Apoptotic Process Myeloid Cell Differentiation Regulation Of Binding Actin Filament Branching Submandibular Salivary Gland Formation Wnt Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Neuron Death Cell Fate Commitment Synaptic Vesicle Targeting Regulation Of Resting Membrane Potential Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Establishment Of Organelle Localization Leukocyte Differentiation Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Establishment Of Golgi Localization Choline Transport Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Protein Catabolic Process Positive Regulation Of Metalloenzyme Activity Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Organelle Localization Neuron Fate Determination Amyloid Precursor Protein Catabolic Process Epithelial-mesenchymal Cell Signaling Positive Regulation Of MAPK Cascade Regulation Of Protein Heterodimerization Activity Immune Response-regulating Signaling Pathway Regulation Of Cell Morphogenesis Keratinocyte Development Regulation Of Synapse Structural Plasticity Regulation Of Cell Projection Organization Positive Regulation Of Kinase Activity Gland Development Regulation Of Cellular Ketone Metabolic Process	Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth RNA 3'-end Processing Respiratory Electron Transport Chain Cholesterol Metabolic Process Adult Locomotory Behavior Positive Regulation Of Mitotic Cell Cycle Regulation Of Receptor Activity
Tagcloud ?		analog assayed bhp butyl chang chop conferred cytoxicity differentially endoplasmic exert flavoprotein hepatocyte hydroperoxide ire1 jnk1 modules nac nfkappab oxidant p50 proteomic relieved reticulum shrna stained tert traf2 viability	502g 786a aciduria acylcarnitine archived autopsies convulsion deteriorated elder enjoyed etfa etfdh father freed friendly glutaric guiding invaluable perimortem postmortem q262r ruled shortly succumbed suspicious travel unexplained unreported v168f
Tagcloud (Difference) ?		analog assayed bhp butyl chang chop conferred cytoxicity differentially endoplasmic exert flavoprotein hepatocyte hydroperoxide ire1 jnk1 modules nac nfkappab oxidant p50 proteomic relieved reticulum shrna stained tert traf2 viability	502g 786a aciduria acylcarnitine archived autopsies convulsion deteriorated elder enjoyed etfdh father freed friendly glutaric guiding invaluable perimortem postmortem q262r ruled shortly succumbed suspicious travel unexplained unreported v168f
Tagcloud (Intersection) ?		etfa