UBE2I and GOLGA2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		UBE2I	GOLGA2
Gene Name		ubiquitin-conjugating enzyme E2I	golgin A2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Synaptonemal Complex Fibrillar Center Nucleus Nucleoplasm Cytoplasm PML Body Dendrite Synapse Transferase Complex Sumoylated E2 Ligase Complex	Golgi Membrane Nucleus Golgi Apparatus Cis-Golgi Network ER To Golgi Transport Vesicle Golgi Cisterna Membrane
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding Transcription Factor Binding Ligase Activity Enzyme Binding Ubiquitin Protein Ligase Binding HLH Domain Binding BHLH Transcription Factor Binding Poly(A) RNA Binding Ubiquitin Protein Ligase Activity SUMO Conjugating Enzyme Activity RING-like Zinc Finger Domain Binding	Protein Binding Protein Kinase Binding Syntaxin Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Chromosome Segregation Mitotic Nuclear Division Regulation Of Receptor Activity Viral Process Protein Ubiquitination Protein Sumoylation Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell Division Positive Regulation Of SUMO Transferase Activity	Mitotic Cell Cycle Negative Regulation Of Protein Binding
Pathways		Post-translational protein modification SUMOylation Meiotic synapsis Processing and activation of SUMO SUMO is transferred from E1 to E2 (UBE2I, UBC9)	Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		258 interactors: ADAR ANXA1 APEX1 AR ARNT ARNTL ATF2 ATF7IP ATXN1 BCAM BEND5 BIRC3 BIRC7 BLM BLMH BMI1 C18orf25 CARM1 CASP2 CASP8AP2 CBLC CBS CBX4 CDC37 CDCA8 CEBPD CEBPE CFTR CHD3 CHFR CHMP1A CHMP4B CHUK CLDN2 CLK2 CORO2A CREB1 CREBBP CREM CSNK2B CTBP2 DACH1 DAXX DES DHX9 DNM1 DNMT3A DNMT3B DRG1 DTX3L DZIP3 EDARADD EDF1 EGR2 ELK1 EP300 ESR1 ETS1 ETV6 EXOSC9 FAS FHIT FHL3 FLI1 FMR1 FOS FOXM1 GCM1 GLUL GMCL1P1 GMEB1 GMEB2 GOLGA2 GOLGB1 GRIP1 HABP4 HDAC1 HDAC4 HDAC5 HDAC7 HGS HIC1 HIPK1 HIPK2 HIPK3 HIST1H4A HIST4H4 HMGN2 HNF4A HNRNPC HNRNPD HNRNPK HNRNPLL HSF1 HSF2 HSF2BP IKZF1 IKZF3 IPO13 JUN KCNK1 KCTD1 KLHL12 KRT19 LMNA LMO2 LNX2 MAP3K1 MAPK1IP1L MARCH5 MDM2 MED7 MGRN1 MITF MKL1 MKRN3 MTA1 MYB NCOR2 NIN NR1D2 NR1H2 NR3C1 NR3C2 NR5A2 NUDCD3 PARK7 PARP1 PDLIM7 PDZK1 PELI1 PEX10 PHC1 PIAS1 PIAS2 PIAS3 PIAS4 PLAGL1 PML PPARA PPARGC1A PPM1J PRKAA2 PRPF40A PSMC3 PTEN PUF60 RAD18 RAD51 RAD52 RAD54B RAD54L2 RANBP2 RANGAP1 RB1 RBBP5 RBBP6 RC3H2 RCBTB2 RFPL3 RIPK2 RNF10 RNF111 RNF115 RNF128 RNF133 RNF144B RNF185 RNF4 RNF40 RORB RPS6KA6 SAE1 SALL1 SATB1 SCNN1A SETBP1 SETD8 SETDB1 SETX SIAH1 SIAH2 SIRT1 SKIL SLC2A1 SLC2A4 SMAD4 SNIP1 SOCS6 SOX10 SOX4 SP100 SP3 SPECC1L SREBF1 SREBF2 SRF STAT1 STRA13 SUMO1 SUMO1P1 SUMO2 SUMO3 SUZ12 TAB2 TAF1 TAF10 TAF12 TAF5 TBP TCF3 TCF7L2 TDG TDP2 TFAP2A TFAP2B TFAP2C TNFRSF1A TOP1 TOPORS TP53 TP63 TP73 TRAF3 TRAF4 TRAF6 TRIM21 TRIM23 TRIM27 TRIM28 TRIM29 TRIM38 TRIM41 TRIM54 TRIM63 TRIM72 TRPS1 UBA2 UBE2K UBXN1 UCHL1 UNC119 USP25 WHSC1L1 WT1 XBP1 XIAP ZBED1 ZBTB16 ZBTB26 ZBTB8A ZCCHC7 ZEB2 ZMYM2 ZNF106 ZNF451 ZNF646 ZNRD1	281 interactors: ABLIM1 ADAP1 AES AFF4 ALKBH3 ALS2CR11 AMOTL2 ANKRD11 ANKRD36BP1 APC ARID5A ARL16 ARL4A ARNT2 ARPC3 ATP6V1C2 ATP6V1D ATP6V1G1 ATXN7 BAHD1 BARD1 BCAS2 BCL6B BMS1P5 BYSL C12orf50 C14orf105 C1orf109 C1orf35 C20orf195 CBX8 CCAR1 CCDC146 CCDC150 CCDC17 CCDC53 CCDC67 CCDC70 CCDC87 CCDC94 CCHCR1 CCNC CCNH CDC20B CDC5L CDC73 CDK1 CDK18 CDKL3 CENPP CEP57L1 CHCHD2 CHCHD3 CINP CORO1A CRMP1 CSPP1 CUL5 CYB5R2 DAXX DCTN4 DCX DDX6 DGCR6 DLGAP5 DLX6-AS1 DMTN DTX2 EIF3G EP300 EXOSC5 FAM110A FAM124B FAM126B FAM184A FAM193B FAM207A FAM214A FAM50B FAM90A1 FBF1 FBXL18 FBXO28 FIP1L1 GATA2 GATAD2B GCC1 GEM GFAP GLYCTK GNG5 GORASP1 GORASP2 GPANK1 GPKOW GPS2 GSE1 GTPBP10 GZMA GZMK HAUS1 HDAC4 HOXB9 HRASLS5 HTRA1 HYLS1 IFT20 IFT27 INPP5J IQCE ISCU ITPKB ITSN2 KANK2 KANSL1 KAT5 KDM1A KIAA1217 KIFC3 KRT18 KRT6A KRT6B KRT6C LASP1 LATS1 LCOR LCP2 LENG1 LGALS3 LIMS2 LIN7A LINGO1 LMO1 LMO2 LMO4 LYPLA1 LYSMD1 MAB21L2 MAGOH MAGOHB MBD3 MCM10 MCM7 MFAP1 MID2 MORF4L1 MORF4L2 MORN3 MOS MSRB3 MTFR2 MVP MYEF2 NCF2 NDE1 NDEL1 NDN NEBL NME7 NOS3 NUDT21 NXT2 ORC1 PARD6B PATL1 PIAS2 PID1 PIK3R2 PIN1 PKN1 PKP4 POLDIP3 POM121 PPP1R16B PPP1R18 PPP2CA PQBP1 PRKAA1 PRKAB2 PRPF31 PSMA1 PSMA4 RAB1A RAB1B RAB2A RAB2B RAB33B RAB39A RAB39B RAB6A RBL1 RBM17 RBM39 RBM41 RCOR3 RGS8 RHNO1 RIBC1 RITA1 RNF135 RNF213 RNF214 RSPH14 RSRC2 RTP5 RUSC2 SAMD4A SAP30BP SCAF8 SCEL SCNM1 SECISBP2 SELV SH2D4A SH3RF2 SHC3 SLU7 SMARCE1 SMCP SNAP47 SNF8 SNRPB SNRPB2 SNRPC SNTA1 SNW1 SPATA2 SPATA22 SRSF2 STAMBPL1 STK25 STK26 SYT6 TBP TCEA2 TCEANC TCF19 TCL1A TEAD4 TFAP4 THAP7 TMED2 TPM1 TPX2 TRIM29 TRIM42 TSC22D4 TSSC4 TSSK3 TTC23 TTC25 TTC9C TUBGCP4 TXLNA UBE2I UBE2U UBE3C USO1 USP2 UTP14C VPS28 VPS37C WDYHV1 YTHDC1 ZBTB16 ZFC3H1 ZFP2 ZFYVE26 ZGPAT ZMAT2 ZNF124 ZNF250 ZNF410 ZNF414 ZNF417 ZNF488 ZNF572 ZNF581 ZNF587 ZNF594 ZNF774
Entrez ID		7329	2801
HPRD ID		09045	03989
Ensembl ID		ENSG00000103275	ENSG00000167110
Uniprot IDs		A8K503 B0QYN7 P63279	Q08379
PDB IDs		1A3S 1KPS 1Z5Q 1Z5S 2GRN 2GRO 2GRP 2GRQ 2GRR 2O25 2PE6 2PX9 2XWU 3A4S 3UIN 3UIO 3UIP
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Gene Expression RNA Metabolic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Metabolic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Regulation Of Cellular Process Protein Ubiquitination Chromosome Organization Response To Organic Substance Metabolic Process Cellular Protein Modification Process Cellular Response To Stress Chromatin Organization Chromatin Modification Peptidyl-lysine Modification Cellular Response To Organic Substance Regulation Of Protein Metabolic Process Cellular Response To Stimulus	Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cell Cycle Organelle Organization Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process MRNA Metabolic Process MRNA Processing RNA Splicing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Mitotic Cell Cycle RNA Processing Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Negative Regulation Of Gene Expression Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Metabolic Process Regulation Of Cellular Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Cycle MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Rab Protein Signal Transduction Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Gene Expression Cell Cycle Process Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Cellular Process Phagosome Maturation Chromosome Organization Cellular Component Assembly Chromatin Modification Chromatin Organization Mitotic Cell Cycle Process Mitotic Cell Cycle Phase Transition Negative Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Phase Transition
Tagcloud ?		array c9orf72 carriers conjugating consisting deregulation discovery displays encode except expansion frontotemporal ftd generalized grn matched preliminary proteasomal proteasome sabiosciences sporadic statistically ube2e1 ube2n ube2q1 ube2z ubiquitin ubiquitination	5p accounts ameliorated ap1 canx chaperones clamp decoy deleterious deregulation disturbances electrical eliminated erg forced former h2o2 hek293 hsc70 micrornas mirnas myocytes patch reciprocal record seed sequestration trafficking upregulation
Tagcloud (Difference) ?		array c9orf72 carriers conjugating consisting discovery displays encode except expansion frontotemporal ftd generalized grn matched preliminary proteasomal proteasome sabiosciences sporadic statistically ube2e1 ube2n ube2q1 ube2z ubiquitin ubiquitination	5p accounts ameliorated ap1 canx chaperones clamp decoy deleterious disturbances electrical eliminated erg forced former h2o2 hek293 hsc70 micrornas mirnas myocytes patch reciprocal record seed sequestration trafficking upregulation
Tagcloud (Intersection) ?		deregulation