SNAP91 and TUBA1B

Number of citations of the paper that reports this interaction (PubMedID 12750376)
0

Data Source:
HPRD (in vitro)

		SNAP91	TUBA1B
Description		synaptosome associated protein 91	tubulin alpha 1b
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Clathrin-coated Pit Synaptic Vesicle Membrane Clathrin-coated Vesicle Extrinsic Component Of Presynaptic Endocytic Zone Membrane	Cytoplasm Cytoskeleton Microtubule Cytoplasmic Microtubule Cilium Microtubule Cytoskeleton
	Molecular Function	SNARE Binding Protein Binding Phospholipid Binding 1-phosphatidylinositol Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein Kinase Binding Clathrin Binding Clathrin Heavy Chain Binding	Nucleotide Binding Double-stranded RNA Binding GTPase Activity Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Hydrolase Activity Ubiquitin Protein Ligase Binding
	Biological Process	Vesicle Budding From Membrane Protein Transport Regulation Of Receptor-mediated Endocytosis Clathrin Coat Assembly Clathrin-dependent Endocytosis Regulation Of Clathrin-dependent Endocytosis	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Cell Division Cellular Response To Interleukin-4
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Recruitment of NuMA to mitotic centrosomes Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cargo trafficking to the periciliary membrane Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin RHOH GTPase cycle HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins PKR-mediated signaling
Drugs			Epothilone D Patupilone CYT997 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Diseases
GWAS		Age-related hearing impairment ( 34108613) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar disorder with mood-incongruent psychosis ( 23092984) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Electrodermal activity ( 25387706) Macular thickness ( 30535121) Refractive error ( 32231278) Schizophrenia ( 28991256 29483656 30285260)	Ambidextrousness ( 32989287) Bipolar disorder ( 31043756) Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287) Left–right brain asymmetry ( 33723403)
Interacting Genes		15 interacting genes: ABI2 AP2A2 AP2B1 DNAJC5 EPS15 ERBB2 ERBB3 ERBB4 GEM MIPOL1 NECAP1 OGT PLCG1 TRAF3IP1 TUBA1B	39 interacting genes: A2M AGTRAP EML4 EPN2 ESR1 FOXP1 FYN GRM7 GZMM HDAC6 ISG15 LINC00624 MAPT MINK1 MTCL1 MYC NFKBIA OGT PFDN5 PIK3R1 PSEN1 PTEN PTP4A1 PTPRF PXN RNF26 RSPH1 RUNX1 SIAH1 SLX1B SMAD2 SNAP91 SRPK2 SUMO2 TERT TMEM253 TOM1L1 TUBG1 WEE2-AS1
Entrez ID		9892	10376
HPRD ID		06391	03960
Ensembl ID		ENSG00000065609	ENSG00000123416
Uniprot IDs		B7Z2N2 E9PDG8 O60641	P68363
PDB IDs			2E4H 5IJ0 5IJ9 5N5N 6E7B 6E7C 6I2I 6J4V 6J8O 6QUS 6QUY 6QVE 6QVJ 6S8L 7LXB 7M18 7M20 7PJF 7SJ7 7SJ8 7SJ9 7SJA 7Z6S 7ZCW 8T42 8U3Z 8V2J 8VA2 8VRJ 8VRK 8VT7 9BP6
Enriched GO Terms of Interacting Partners?		Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Postsynaptic Neurotransmitter Receptor Internalization Vesicle-mediated Transport In Synapse AP-2 Adaptor Complex Epidermal Growth Factor Receptor Signaling Pathway Basal Plasma Membrane Clathrin-coated Pit ERBB3:ERBB2 Complex ERBB Signaling Pathway ERBB2 Signaling Pathway Neuregulin Receptor Activity ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Presynaptic Endocytosis Cellular Response To Epidermal Growth Factor Stimulus Peptidyl-tyrosine Phosphorylation Response To Epidermal Growth Factor Postsynaptic Endocytic Zone ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Positive Regulation Of Epithelial Cell Proliferation Receptor Internalization Clathrin Adaptor Complex Neuromuscular Junction Clathrin Adaptor Activity Endolysosome Membrane Heart Development Schwann Cell Development Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Post-anal Tail Morphogenesis Cytoplasmic Side Of Plasma Membrane Clathrin Coat Assembly Clathrin-coated Endocytic Vesicle Protein Tyrosine Kinase Activity Peripheral Nervous System Development Membrane Coat Clathrin-dependent Endocytosis Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse Regulation Of Epithelial Cell Proliferation Cellular Localization Establishment Of Localization In Cell Receptor-mediated Endocytosis Synaptic Vesicle Endocytosis Endocytosis Growth Factor Binding Receptor Complex Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Establishment Of Planar Polarity Involved In Nephron Morphogenesis	Negative Regulation Of Developmental Process Beta-catenin Binding Neuron Projection Organization Negative Regulation Of Cellular Component Organization Regulation Of Myeloid Cell Differentiation Regulation Of Cellular Component Organization Regulation Of Multicellular Organismal Development Negative Regulation Of Multicellular Organismal Process Regulation Of Developmental Process Regulation Of Signal Transduction Regulation Of Cell Development Regulation Of Cell Communication Regulation Of Signaling Response To Stress Regulation Of Anatomical Structure Morphogenesis Negative Regulation Of Cell Differentiation Regulation Of Protein Localization To Nucleus Enzyme Binding Negative Regulation Of Cell Development Positive Regulation Of Protein Oligomerization Negative Regulation Of Signal Transduction Negative Regulation Of Protein Metabolic Process Growth Factor Receptor Binding Dendritic Spine Organization Ubiquitin Protein Ligase Binding Negative Regulation Of Myeloid Cell Differentiation Organelle Organization Clathrin Binding Negative Regulation Of Hydrogen Peroxide Metabolic Process Positive Regulation Of Protein Localization To Nucleus Negative Regulation Of Cell Communication Negative Regulation Of Signaling Neuron Projection Development Positive Regulation Of Signaling Regulation Of Multicellular Organismal Process Neuron Projection Regulation Of Cell Differentiation Cellular Response To Reactive Oxygen Species Cellular Response To Stress Alpha-tubulin Binding Tau Protein Binding Postsynapse Organization Positive Regulation Of Signal Transduction Positive Regulation Of Cellular Component Organization Regulation Of Protein Localization Negative Regulation Of Gene Expression Protein Modification Process Regulation Of Establishment Of Protein Localization Inclusion Body Assembly Regulation Of Myeloid Leukocyte Differentiation
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