TRIML2 and KRT38

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRIML2	KRT38
Description		tripartite motif family like 2	keratin 38
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Protein Ubiquitination Response To Retinoic Acid Innate Immune Response	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Polycystic ovary syndrome ( 25574032)
Interacting Genes		46 interacting genes: ABI2 BLOC1S2 CBY2 CCDC146 CCHCR1 CCNH CDR2 CTBP2 EIF2B1 EIF3M FAM90A1 FAM9C HGS ING5 ITGB3BP KRT15 KRT24 KRT27 KRT31 KRT34 KRT38 KRT75 MBD3L2 MBD3L3 MEOX1 MEOX2 NECAB2 NFKBID NUP62 PICK1 POLR1H POU6F2 SH2D4A STN1 SUMO2 SYCE2 TBC1D25 TCF4 TFIP11 TRIM54 TSEN54 TSG101 USHBP1 XAF1 ZBED1 ZFHX3	72 interacting genes: - ABI3 AMOTL2 ANKRD36BP1 BEX2 BRME1 C1orf216 CCDC120 CCDC146 CD300A CEP57L1 DMRT3 DTNB FAM110A FAM90A1 GLRX3 GNG10 GNG13 HAUS1 HDAC4 HGS HMG20B HOXA1 HSF4 KDM1A KIFC3 KLHL38 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT86 LHX4 LMO3 LMO4 MAGEB4 MAPKBP1 PIK3R2 PIN1 POU4F2 PSMA1 PSMC5 PTGER3 RHPN1-AS1 SCNM1 SMARCD1 TBC1D21 TRIML2 TXLNA TXLNB TXNDC5 USHBP1 UTP23 ZFYVE21 ZNF20 ZNF417 ZNF587
Entrez ID		205860	8687
HPRD ID		08696	05176
Ensembl ID		ENSG00000179046	ENSG00000171360
Uniprot IDs		A0A804HJA0 B7ZLC3 Q8N7C3	O76015
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Protein Binding Supramolecular Fiber Organization Somite Specification Epithelial Cell Differentiation Cytoskeleton Morphogenesis Of An Epithelium Cytoskeleton Organization Organelle Organization Cellular Developmental Process Tissue Morphogenesis Segment Specification Somite Development Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion	Structural Constituent Of Skin Epidermis Keratinization Intermediate Filament Organization Keratin Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Supramolecular Fiber Organization Organelle Organization Protein Binding Extracellular Exosome Intermediate Filament Cytoskeleton Epidermis Development
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